Sophie de Carné (she/her)

YouTube video by Francis Crick Institute The Past, Present and Future of Immunology Research – with Caetano Reis e Sousa

Join Caetano Reis e Sousa (@reisesousalab.bsky.social) as he describes how our immune systems work and his team’s research into better understanding dendritic cell receptors. www.youtube.com/watch?v=nBC9...

I agree, Larry. I use it to get an overview of something I am not familiar with. I brainstorm with it. I ask for “brutally honest feedback” with a prompt that makes it challenge my thinking.
But I would not make it generate text from scratch. I have tried and it isn’t helpful.

Writing is thinking. A reminder on why scientists write, and why we should continue writing in the era of large-language models by Nature Review Bioengineering

@natureportfolio.nature.com
www.nature.com/articles/s44...
#AI #LLM 🧪

Depends… Does it have a bottle opener? 😅

How exercise during pregnancy can improve metabolic health of offspring: a key mediator (Serpina3c) from mother's white adipose tissue gets into fetal circulation, suppresses inflammation, as demonstrated in the mouse model
www.nature.com/articles/s42...
www.nature.com/articles/s42...

Thrilled to announce I'm moving to Manchester to lead the Cancer Origins group! If you're interested in how mutations and exposures drive tumourigenesis — come join the adventure

Very important and timely statement from @miriammerad.bsky.social, president of IUIS.

This has been the most productive 🇬🇧🇫🇷 Summit since Lancaster House 2010. With next week’s 🇬🇧🇩🇪Summit and Defence Treaty, it marks the final laying of the Brexit ghost, at least in terms of bilateral links with EU countries. The combination of Putin and Trump has made this essential. A 🧵

Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer - Nature Cancer Using pancreatic organoids and genetic mouse models, Antonucci et al. show that cellular stress activates an NRF2–EZH2 epigenetic axis leading to metabolic reprogramming and subsequent malignant trans...

🚨New Article Alert from Nature Cancer !

'Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer'
✏️ By Michael Karin and colleagues

🔗 www.nature.com/articles/s43...

Clinicogenomic landscape of #PDAC identifies KRAS mutant dosage as prognostic of overall survival
@NatureMedicine
doi.org/10.1038/s415...
👉Very comprehensive analysis on the impact of KRAS
👉Key for understanding de novo and acquired resistance to RAS 💊
@myESMO

So climate change is causing people to become allergic to one of the very things that contribute to it? How very fascinating 🤓
#Gaia #ClimateChange

Hey. Huge congrats on your new position, Tom! 🎓

Diversity is a driver for discovery 💡
Thank you, Pasteur et al., for promoting diversity in science 🏳️‍🌈🏳️‍⚧️💪🧪
#DiversityInScience

Calling all early-career RAS biology scientists!

🧬 Want to showcase your research? Submit your abstract for #TargetingRAS2025 by July 15th for a chance to take part in Short Talks.

Connect, get feedback, and shine among experts! Ready to step up? 🌟 More info: https://targetingras.com/registration/

Members of the MILI Trial team are attending the 2025 CRUK Cancer Prevention Research Conference this week.

@cancerresearchuk.org @oxfordcancer.bsky.social
#CRUK #LFS

Thrilled to announce that I’m joining the 2025 Franco-British Young Leaders Programme!
Looking forward to building bridges between science, society, and institutions across my two countries 🇫🇷🇬🇧

2025 Young Leaders announced francobritish.org/en/2025-youn...

We are recruiting! We're searching for a postdoctoral research fellow to study patient-specific regulators of plasticity in primary and metastatic CRC. Please reach out if you have any questions! www.ucl.ac.uk/work-at-ucl/...

🎤 Meet Our Speaker: Dr. @sdecarne.bsky.social, from Institut Gustave Roussy (Villejuif, France) as a speaker at the Targeting RAS Symposium 2025.

Dr. de Carné will give her talk during Session 3 on Day 1 at 15:00 

🔗 Register: https://targetingras.com/registration/

#TargetingRAS #25anniversaryCIC

YouTube video by ZhengLabProductions Zheng Lab - Bad Project (Lady Gaga parody)

Brilliant. It reminds this cover of a Lady Gaga song 🪩

youtu.be/Fl4L4M8m4d0?...

A Villejuif, au pied de l’Institut Gustave-Roussy, l’éclosion d’un quartier consacré à la lutte contre le cancer Depuis 2022, le Paris Saclay Cancer Cluster porte le projet de faire de cette zone un fer de lance français de la recherche et du développement industriel en oncologie. Les premiers bâtiments ont comm...

📰 À @villejuiffi.bsky.social, au pied de @gustaveroussy.fr, l’éclosion d’un quartier consacré à la lutte contre le #cancer.

Un article de Zeliha Chaffin à lire dans @lemonde.fr ⤵

We are looking for a candidate to apply for the FRM postdoctoral fellowship in late May. Join our thyroid cancer genetics and biology group at @gr-research.bsky.social

If interested, please see details in attached file and reach out to inigo.landa@gustaveroussy.fr

drive.google.com/file/d/1qY1r...

Tumor-Infiltrating Clonal Hematopoiesis | NEJM Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencie...

New evidence that age-related clonal hematopoiesis (CHIP) drives solid cancer progression by remodelling the tumour immune microenvironment. Out in @nejm.org
Congrats @oriolpich.bsky.social, @elsabernard.bsky.social, Maria Zagorulya, @charlesswanton.bsky.social et al.

www.nejm.org/doi/full/10....
🧪

@gustaveroussy.fr prend part à la trend ! ✌

L’Institut recrute tout au long de l’année des talents dans le médical, le médico-technique, le paramédical, la petite enfance, l’administration ou le secrétariat médical.

⬇

Diabetes can impact cellular immunity in solid tumors Cancer is increasingly prevalent worldwide, often coexisting with type 2 diabetes (T2D). Recent breakthroughs reveal the immune system’s pivotal role in eliminating tumors and how the metabolic enviro...

How does diabetes impact cellular immunity in solid tumours? Trends in Immunology www.cell.com/trends/immun...

Falsely Accused | Justice by Genomics Jailed for killing her children, freed by advances in genomics - Kathleen Folbigg joins experts to explore what can be learnt from her case.

Jailed for killing her children, freed after twenty years by advances in genomics - Kathleen Folbigg joins experts to explore what can be learnt from her case.

Register now for free tickets to our event discussing genomics in criminal trials:

www.eventbrite.co.uk/e/falsely-ac...

154 million lives and counting: 5 charts reveal the power of vaccines But public-health specialists worry that misinformation and funding cuts could affect vaccination rates.

The power of vaccines. www.nature.com/articles/d41...

1) KRYSTAL-7 update on pembro+adagrasib in 1st line pdl1 >50% nsclc. Tox to navigate but mPFS >27m! Further reinforcing the view that ras orchestrates TME, not just cancer cell intrinsic pathways. Massive congrats to investigators, mirati, bms #ELCC25

If you are interested in doing a PhD in my lab at Gustave Roussy/Paris-Saclay, we have just posted potential thesis projects in ADUM (adum.fr/index.pl).

If interested, send me an email at inigo.landa@gustaveroussy.fr with your CV, short motivation letter and contact info for 2-3 references.

We are recruiting for a new Research Technician to join the @cruk-cityoflondon.bsky.social Organoid Platform!

Full details at: www.ucl.ac.uk/work-at-ucl/...

The silent battle to address the health crisis of conflict-induced air pollution - Nature Medicine Conflict zones are plagued by air pollution from warfare-related activities, which exacerbates public health challenges, especially for vulnerable populations and the environments they live in.

A Comment article in Nature Medicine discusses how conflict zones are plagued by air pollution from warfare-related activities, which exacerbates public health challenges, especially for vulnerable populations and the environments they live in. 🧪