Adam Byron

Just don't mention Root getting a century!

Want to know what it’s like to study an MB-PhD?🧑‍🔬💡

Watch this Day in the Life with Jean, a @manchester.ac.uk medicine undergrad who has taken time out to complete a PhD in Cancer Sciences.

And explore our current MB-PhD projects: ow.ly/1fSo50Ttypu

ow.ly/x0ZX50TtykG

Commentator's curse 😨

"are you enjoying duo mobile" does a hamburger enjoy being made of quarks. does a fish enjoy linear time. does the mountain enjoy the first taste of a cup of hot chocolate when you get back to the ski lodge. your question means nothing to me. i couldn't enjoy duo mobile even if i tried

I am super happy to see this published in @jcb.org ! If you are interested in cell adhesion and trafficking go have a look !

Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB @ascbiology.bsky.social in Philadelphia. Just drop me a line.

Image screening is going to fail. We need audit trails for data provenance.

Got that warm-up game in, at least 🏏 #AUSvsENG #Ashes #Cricket

Today has been a great three days of Test cricket. #Ashes 🏏

MRC Doctoral Training Partnership Find out more about the Medical Research Council (MRC) Doctoral Training Partnership (DTP) studentships for postgraduate researchers undertaking PhDs in biomedical, clinical and health services areas.

Two days left to apply for a Medical Research Council-funded PhD opportunity in the lab. This is a student-led project, so you can work with us to develop an exciting project in a research area of mutual interest! www.bmh.manchester.ac.uk/study/resear...
@mcf-uom.bsky.social @fbmh-uom.bsky.social

The cover of CRICK

Nice endpapers showing Crick and Brenner’s blackboard

Section pics that bleed off the page

Colour plate of Crick looking dreamy on the beach at Cold Spring Harbor, 1954.

UK publication day for this wrist-spraining beauty! Appropriately, I’m travelling to Cambridge, where I’m doing a book launch talk at the LMB tomorrow afternoon.

Let's go! Super excited to partner with @richardsever.bsky.social and the fantastic @openrxiv.bsky.social team - Preprints have been the best thing that happened to science publishing during my lifetime, and we're happy @qedscience.bsky.social can make preprints do more 👊

Enabling options for review: from training and transparency to author-centered AI tools - openRxiv Peer review is widely viewed as a critical aspect of biomedical communication. Ideally, it provides authors with feedback so they can improve manuscripts and gives readers, particularly nonspecialists...

Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n

openrxiv.org/enabling-rev...

We have a new academic post opening for a Lecture/Senior-Lecturer in Structural Biology @mcf-uom.bsky.social @fbmh-uom.bsky.social @manchester.ac.uk The University of Manchester is ranked among the top Universities worldwide. QS world rankings: 34th (2025)

www.jobs.manchester.ac.uk/Job/JobDetai...

Graham Pavitt

We are excited to announce that Professor Graham Pavitt, Chair in Molecular Biology, has been appointed as our new Head of Division!
Join us in welcoming Graham to his new role—we look forward to the exciting times ahead!

research.manchester.ac.uk/en/persons/g...

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

The chemistry community should ban drawing chemical structures with generative AI, chemists warn AIs like Microsoft's Copilot, Google's Gemini and OpenAI's ChatGPT still make serious errors rendering structural formulae

Chemists call for ban on generative AI for chemical structures: "serious errors could damag[e] the next generation of scientists"

As ever, the problem seems to be not AI but lazy application of it and lack of checks. Whether _that_ problem is solvable...

www.chemistryworld.com/news/the-che...

Fantastic time at the Adhere2 conference on cell adhesion - on the lovely Dalmatian coast.

#CellBiology #research #conference

The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate - Nature Cell Biology Marin et al. report the role of lamin proteins and the lamin B receptor (LBR) in chromatin positioning at the nuclear periphery. Knockout of all lamins and LBR in mouse embryonic stem cells leads to h...

Another paper bluetorial! Today: how does the spatial location of genes influence their function? (1/n) www.nature.com/articles/s41...

🎉 Happy International #EpithelialMechanics Day! 🎉

Several members of the Tumor Immunology and Immunotherapy team from the Regina Elena National Cancer Institute in Rome gathered around a table.

Just back from a fantastic research visit to the Regina Elena National Cancer Institute, Rome, working with Dr Paola Nisticò and the Tumor Immunology & Immunotherapy team 🔬
Amazing cancer biology research, inspiring discussions and such warm hospitality from the team ☀️
#CancerResearch #Collaboration

Patterning of cell identities in the posterior E8.5 mouse embryo. Co-expression of mesoderm marker TBXT (blue) and neural marker SOX2 (green) identifies cells in the neuromesodermal (NMP) progenitor region at the intersection of their respective gene expression gradients. TBX6 (red) marks paraxial mesoderm and also marks sporadic mesoderm-committed cells emerging within the NMP region. LAMINB1 (white) marks the nuclear envelope of all cells. Credit: Matthew French.

Measuring properties of individual cells in relation to their neighbors in 3D tissues is challenging. @cellysally.bsky.social &co develop a computational toolkit to facilitate this, analyzing developmental patterning in mouse, chick & #Drosophila #embryo @plosbiology.org 🧪 plos.io/4lQMeNu

So excited to FINALLY be able to share exciting news from @lydiabeckeriii.bsky.social on our newly awarded MRC Centre of Research Excellence (MRC CoRE) in Exposome Immunology #ImmunoSky 🧪 🧵

EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different c…

Excited to share our most recent study on #integrintraffic #cancer #migration #focaladhesion by @ivaskalab.bsky.social @drpaulinamoreno.bsky.social Niklas Jäntti et al www.sciencedirect.com/science/arti...

Mechanical stress and caveolin-1 control the release of extracellular vesicles with increased tumorigenic properties Mechanical forces within the tumor microenvironment critically influence cancer progression, in part by modulating extracellular vesicle (EV) dynamics. However, the molecular mechanisms by which EVs r...

💥 Our latest @biorxivpreprint.bsky.social is out !
👉 www.biorxiv.org/content/10.1...

The first, first-author story www.biorxiv.org/content/10.1... from @felkohdigital.bsky.social & www.cancersystemsmicroscopylab.com exploring how the epithelial-mesenchymal (E/M) state landscape pre-determines EGF signalling responses. An analytical tour-de-force, with more to come on this theme!

Publishing scientific papers is an obstacle course. There are many aspects to this but lengthy review times are one. That's why I am very excited about the new initiative @biologyopen.bsky.social, @biologists.bsky.social open access journal: Fast & Fair 1/n 🧪
journals.biologists.com/bio/pages/fa...

Ooh, very interesting 🔬 (And great pseudo-acronym coined!)

🏏😮

It was, indeed, quite warm ☀️🌡️
A really rewarding exchange that sparked lots of new ideas for collaborative research projects 🔬 💡
Thanks so much to the inspiring team in Rome! 🇮🇹 🌍