Max Ruwolt

Big congrats to my colleagues upstairs! Great work now published in @natchem.nature.com. Always happy to run #proteomics experiments with you. 🤝

AIRPred: A Deep Learning Model Predictor for Peptide Intensity Ratios in Cross-Linking Mass Spectrometry Improves Cross-Link Spectrum Matching pubs.acs.org/doi/10....

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#proteomics #prot-paper

Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation - Nature Chemistry Our understanding of how post-translational modification—protein phosphorylation—impacts the complexity of eukaryotic signalling pathways is continuously expanding. Now, protein oligophosphorylation h...

Brace yourselves! Arif from the Fiedler lab discovered+characterized in collaboration with us & other groups within the @fmp-berlin.de a novel PTM: autocatalytic oligophosphorylation (up to 6 Phosphates 😲). Still mysterious in origin, function & regulation.

www.nature.com/articles/s41...

Thank you @nesvilab.bsky.social, it indeed became an invaluable tool throughout this and other projects that we're working on.

A fun little side project from our FMP MS platform just got published! Previously, we struggled with messy Excel sheets to monitor machine performance and allocate machine time to users. Now, Q2C combines those management tasks into one user-friendly, GUI-based software. 💻

Structural host-virus interactome profiling of intact infected cells - Nature Communications Virus-host protein-protein interactions are fundamental to viral pathogenesis, yet few are structurally resolved. Here, the authors combine cross-linking mass spectrometry, bio-orthogonal labeling and...

Check out Structural Host–Virus Interactome Profiling (SHVIP) in intact cells infected with Herpes Simplex Virus type 1 (HSV-1)! Now published!

📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec