Heading home after a rich day full of science at @institutpasteur.bsky.social. Warm thanks to @julianbuchrieser.bsky.social and Olivier Schwartz for the kind invite!
10.01.2026 07:15 — 👍 5 🔁 0 💬 0 📌 0@goffinetlab.bsky.social
Chair in Virology @LSTM, UK | HIV-1, alphaviruses, SARS-CoV-2, MPXV | AIVE - Antiviral Immunity and Viral Evasion | Alumna of Charité - Universitätsmedizin Berlin, Germany https://www.lstmed.ac.uk/about/people/professor-christine-goffinet
Heading home after a rich day full of science at @institutpasteur.bsky.social. Warm thanks to @julianbuchrieser.bsky.social and Olivier Schwartz for the kind invite!
10.01.2026 07:15 — 👍 5 🔁 0 💬 0 📌 03/ in "shock-and-kill" approaches, as we found (link to studies below). Indeed, the authors don't seem to generate evidence for detectable reduction of the reservoir size, and (temporal) virus control seems to be achieved predominantly by T-cell responses. #HIVCure is not around the corner!
23.12.2025 19:10 — 👍 1 🔁 1 💬 1 📌 02/ special profile from start on which may potentially have facilitated things). I really do wonder if the chosen LRA, the TLR9 agonist lefitolimod, modulates cell surface Env presentation (important for ADCC), and/or apoptosis. Many (but not all!) LRAs do, and paradoxically impede "kill"
23.12.2025 19:10 — 👍 1 🔁 1 💬 1 📌 01/ I agree that (even functional) #HIVCure will probably need a multi-component and staged strategy, and is not close. This multi-pronged approach shows, 18 months post ATI, a delay of viral rebound in 6/9 participants, and remission in 1/9 participants (though the latter seems to display a
23.12.2025 19:10 — 👍 1 🔁 1 💬 1 📌 0Definitely exciting and even more puzzling. Note that the patient himself was heterozygous for CCR5delta32. So either there is a dosage effect of truncated CCR5, and/or (more provocative) the CCR5 genotype is less relevant than we all anticipated and the allo-SCT per se does large part of the trick?
23.12.2025 18:09 — 👍 2 🔁 1 💬 1 📌 0Last month, my team had the great pleasure of hosting a fantastic guest PhD student, Bridget Fisher, from Sharon Lewin's lab at The Peter Doherty Institute for Infection and Immunity, for our collaborative work on #HIVCure. Looking fwd to continuing this exciting joint study. Very well done Bridget!
23.12.2025 17:25 — 👍 5 🔁 1 💬 1 📌 0Absolutely privileged to have met Michel Sidibé, AU Envoy for African Medicines Agency, former @unaids.org Director & Mali Health Minister. Our chat spanned topics ranging from #HIVcure development to implementation. Should a cure be discovered, do we have systems to ensure equitable access?
10.12.2025 17:12 — 👍 4 🔁 0 💬 0 📌 0Dylan Postmus giving a presentation on his work at the RetroPATH meeting
View from a boat ride on the Neckar River in Tübingen, Germany.
Had an excellent time at this year’s #RetroPATH2025 meeting in Tübingen, Germany, talking about my work on #HIVcure. Many thanks to @agschindler.bsky.social and Daniel Sauter for hosting. Especially interesting was the variety of talks on #HERVs @goffinetlab.bsky.social @lstmnews.bsky.social
19.10.2025 21:16 — 👍 5 🔁 2 💬 1 📌 0I am very pleased to be hosting @goffinetlab.bsky.social from @lstmnews.bsky.social tomorrow, sponsored by @infect-net.bsky.social
📣: Feodor-Lynen lecture hall @genecenter-lmu.bsky.social
🕙 18.9. 1:00 pm
Many thanks Prof Henry Mwandumba and Prof Kondwani Jambo & teams for the warm welcome and hospitality at Malawi Liverpool Wellcome Research Programme, Blantyre. We had fantastic discussions and developed prospects for collaboration on #HIVCure. A truly inspiring visit!
08.09.2025 17:42 — 👍 8 🔁 2 💬 0 📌 0We had a great time hosting three college students - Sadie, Chloe and Isobel - as part of the In2STEM programme with Dr Kelly Johnston. With @dylanpostmus.bsky.social, they learned about our work in #HIVCure, drug development pipelines and assay design. Check out the programme here: in2scienceuk.org
11.08.2025 08:57 — 👍 2 🔁 1 💬 0 📌 0Congratulations to @juliaprigann.bsky.social for being awarded the 2025 CFAR Excellence in Basic/Translational Science Award!
cfar.ucsf.edu/user/11703
En route pour Lyon. Je me réjouis de présenter quelques snapshots de notre recherche @lstmnews.bsky.social sur le Chikungunya virus #CHIKV et son interaction avec le système immunitaire inné! #JFV2025
23.04.2025 17:02 — 👍 4 🔁 1 💬 0 📌 0An inspiring meeting #KSHIV25 in Durban ends. Great presentation by @dylanpostmus.bsky.social on why many LRAs for #HIVCure are imperfect. A pleasure meeting the next promising generation of African ECRs, speaking to old friends and making new ones. Plus the daily sunrise over Indian Ocean!
10.04.2025 19:38 — 👍 4 🔁 1 💬 0 📌 0Shout-out to @dylanpostmus.bsky.social speaking at #MicroBio25. Just in time before heading to Keystone Symposium on #HIVCure keysym.us/KSHIV25
Stay tuned!
Happy to be part of the EU consortium DEFENDER @horizoneu.bsky.social and contribute to discovery of novel entry factors of #CHIKV, laying the ground for development of antiviral therapies @lstmnews.bsky.social
25.03.2025 08:54 — 👍 4 🔁 1 💬 0 📌 0#InternationalWomensDay2025
“When I’m sometimes asked 'When will there be enough?’ and I say ‘When there are nine,’ people are shocked. But there'd been nine men, and nobody's ever raised a question about that.”
Ruth Bader Ginsburg
1933-2020
It was a pleasure attending #GfV2025 in Hamburg today and chairing the Innate Immunity Plenary today together with @sparrerlab.bsky.social with fantastic keynotes by Adolfo García-Sastre, @scheellab.bsky.social and Michaela Muller-Trutwin. Thanks for coming!
07.03.2025 12:36 — 👍 13 🔁 2 💬 0 📌 0Due to high interest in the role, the ad will be kept live until March 9th:
25.02.2025 12:00 — 👍 0 🔁 0 💬 0 📌 0Deadline for submission of applications for the role of Chair in Immunology at @lstmnews.bsky.social is March 2nd 👇
13.02.2025 20:52 — 👍 0 🔁 0 💬 0 📌 0Join me at the LSTM in Conversation Webinar with Barry Atkinson @ukhsa.bsky.social and @gsrajahram.bsky.social in less than two days!
Sign up via the link in the description 👇
Of course, costs for Skilled Worker VISA application and NHS surcharges will be covered by LSTM.
29.01.2025 22:18 — 👍 0 🔁 0 💬 0 📌 0We @lstmnews.bsky.social are looking to appoint a Professor of Immunology with strong record in human pathogen and/or tropical disease research for translation of basic science into tangible solutions for the patients affected by global health challenges:
app.vacancy-filler.co.uk/salescrm/Car...
📢Post-Doctoral Research Associate Position (2.5 years with prospect of extension) on alphavirology at @lstmnews.bsky.social, Liverpool, UK - Characterisation of cellular entry inhibitors of #CHIKV within starting @horizoneu.bsky.social Consortium DEFENDER📢
app.vacancy-filler.co.uk/salescrm/Car...
Happy to be part of the new Horizon EU consortium DEFENDER and to start characterising CHIKV-modulating cellular factors and their druggability!
15.01.2025 17:17 — 👍 3 🔁 0 💬 0 📌 0@lstmnews.bsky.social is recruiting a Full Professor in Immunology. If you are interested in developing a competitive and impactfull research programme in the field of immune control of tropical diseases, in a vibrant scientific environment, please reach out!
app.vacancy-filler.co.uk/salescrm/Car...
Will make sure to provide support for VISA/IHS costs
19.10.2023 11:30 — 👍 0 🔁 0 💬 0 📌 0💥 Postdoc position advert in the making (to be filled early 2024 Liverpool School of Tropical Medicine): if you are interested in investigating arthritogenic alphavirus infections in human cells and mosquitoes, with a focus of cell-intrinsic innate immunity, sensing and viral evasion, stay tuned 💥
19.10.2023 11:29 — 👍 1 🔁 1 💬 1 📌 0