Why would the canonical microcircuit do predictive coding when mechanisms like ephaptic coupling are emergent? Cognitive models for local circuits that donโt address biophysical mechanisms are not okay. ๐งช
www.cell.com/neuron/fullt...
@neuronasko.bsky.social
CUNY neuroscience PhD candidate. Interested in comp neuroscience, comp social science, causality, and philosophy of science. Previously at UMich[as visiting student]/Stanford/ETH Zurich & UZH/UIUC. Opinions are my own.
Why would the canonical microcircuit do predictive coding when mechanisms like ephaptic coupling are emergent? Cognitive models for local circuits that donโt address biophysical mechanisms are not okay. ๐งช
www.cell.com/neuron/fullt...
PS: Ernst Niebur, one original authors of the Koch and Itti paper in visual salience maps, has been still working on the grouping hypothesis and Anne Treismanโs ideas to solve the binding problem in the visual system. Takeaway is, bottom-up gestalt mechanism and top-down integration need to merged.
08.10.2025 13:40 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0Hypothesis: Anne Treismanโs integration theory hypothesis for top-down control (the archaic term was โattentionโ in systems neuro sphere) becomes the default mechanism for handling representation as one goes up the cognitive hierarchy.
08.10.2025 13:33 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0Hypothesis: More abstract grouping cell behavior is better defined in the hippocampus than in V1 through V4 or even S1. In other words, place and grids cells are comparatively more complex representations than simple/complex/border-ownership selectivity cells. Some may argue this is obvious.
08.10.2025 13:16 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0PS: Representational drift of V1 tuning curves takes weeks in mice.
โSensory experience steers representational drift in mouse visual cortexโ
www.nature.com/articles/s41...
Conjecture: What if representational drift also affects grouping cells in visual binding? What if functional grouping of cells representational drift goes as low as V1/V2 given mixed selectivity?
08.10.2025 12:42 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0Once my current project finishes, Iโm not going back to MATLAB unless itโs actually needed for the job at hand or old code needs to unkept/translated. Good software for many things but the licensing model has become ridiculous.
07.10.2025 19:22 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0To deny perceptual binding via oscillations or binding-by-synchrony is an extraordinary claim. ๐งช
โSolving the binding problem: Assemblies form when neurons enhance their firing rateโthey donโt need to oscillate or synchronizeโ
www.sciencedirect.com/science/arti...
Well then we have ourselves a bit of conundrum because neurons control/model their own inputs which means they have knowledge about system-wide function. System motifs scale from neuronal to higher levels because itโs all distributed and highly self-referential, including social interactions.
06.10.2025 16:27 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0Actually no, this is debate because you making comments on how neurons work. Iโm tying top-down control across systems.
06.10.2025 16:08 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0(Sorry meant to they do connect to motor action via general frameworks of top-down control.)
06.10.2025 13:34 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0Yes they do and Iโd like to engage but I canโt take debates with seriously because of your dislike of neuroscientists.
06.10.2025 13:31 โ ๐ 0 ๐ 0 ๐ฌ 2 ๐ 0PS: This phenomenon as a well for athletes and race car drivers is related to the mindโs eye.
appliedsportpsych.org/resources/re...
This feels related to these two papers:
โDoes neural computation feel like something?โ
www.frontiersin.org/journals/neu...
โPhysics versus graphics as an organizing dichotomy in cognitionโ
www.sciencedirect.com/science/arti...
Do attractor networks in the brain emerge based on how information from input flows (attractors are observed) or does the brain emulate attractors like some internal model to do computations (attractors are built)?
[The former is just so much more parsimonious.]
www.nature.com/articles/s41...
โChallenges in Statistics: A Dozen Challenges in Causality and Causal Inferenceโ
arxiv.org/abs/2508.17099
Now Morocco!! This happened in Nepal just weeks back and itโs starting up again elsewhere. It was evident back in the spring that 2025 had 1989 vibes. I will stay on the annoying optimist hill. Lampoon the doom.
Still watching Serbia, Hungary, Turkeyโฆ
www.lemonde.fr/en/le-monde-...
๐ช๐ฎ๐ป๐ ๐๐ผ ๐น๐ฒ๐ฎ๐ฟ๐ป ๐ฎ๐ฏ๐ผ๐๐ ๐ต๐๐บ๐ฎ๐ป ๐ฎ๐ณ๐ณ๐ฒ๐ฐ๐๐ถ๐๐ฒ ๐ป๐ฒ๐๐ฟ๐ผ๐๐ฐ๐ถ๐ฒ๐ป๐ฐ๐ฒ?
This is massive, a lot of great material.
Huge amount of work to put this together, many thanks to Jorge and Patrik for getting the second edition out.
Thanks for clarifying.
It might just thermodynamically cheaper for brains to behave this way to find novelty? What natural stimuli behaves like a noisy-TV? Itโs like using high fructose corn syrup to artificially sweeten foods and trick the brain into thinking itโs finding a scarce resource.
PS: I have been thinking that anticipation of AGI is illiberal thinking.
29.09.2025 03:23 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0I donโt understand if the AGI argument is real?
29.09.2025 03:08 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0Having been always hands on with the data I work with, Iโve found that my unconscious pattern matching has become more theoretical. Imagine doing data analysis so much you can compare yourself to ML algorithms.
28.09.2025 17:47 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0Why do so much faceless/abstract corporate entities have so much say in my social/professional life?
For example: How are FICO scores determined? Why do I have to give up my information to third parties? Why is student debt not treated as a monopoly? Why do insurance companies have so much power?
If we had this conversation a few years ago Iโd agree. The current crisis was inevitable and the current leadership is a nasty catalyst. There is no way the grant funding model for science and its centralized agencies were going to survive globalization. Same goes for the science journal monopolies.
28.09.2025 01:13 โ ๐ 2 ๐ 0 ๐ฌ 1 ๐ 0There is no such distraction. Systems evolution is not something you control.
28.09.2025 00:51 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0Itโs actually both lol. I was being a bit categorical there, itโs all about systems evolution if you ask me, so we need new definitions across all thought, especially for computation. If you disagree, thatโs fine too. As long as the dialectic continues, self-organization takes precedent.
28.09.2025 00:33 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0I canโt follow because thatโs the kind of policy that doomed science progress.
โKnowingโ will always socially usurp existing power structures because people become anti-establishment. People are โanti-realistโ by their innate nature because โknowingโ is a thermodynamically cheap policy.
[Is rejecting โknowingโ a deception?]
27.09.2025 23:28 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0Okay, but how does this relate to anything being anti-Searle.
27.09.2025 22:22 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0What about an abstract sandbox in which I can lay out different sequences of strategy one and two? See I can use my own brain to layer levels of Turing Tests.
27.09.2025 22:02 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0