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Mikhail Shapiro

@mikhailshapiro.bsky.social

Bio-Acousto-Magneto-Neuro-Chemical Engineer Max Delbrück Professor @Caltech Investigator @HHMI Fulbright-Tocqueville Chair @PhysMedParis @ESPCI_Paris '24-5 shapirolab.caltech.edu

842 Followers  |  228 Following  |  2 Posts  |  Joined: 16.11.2024  |  1.4329

Latest posts by mikhailshapiro.bsky.social on Bluesky

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Can we make a brain tumor visible under ultrasound? 🧠 🔉 Yes, using intravenous #gasvesicles! This can help guide brain surgery and monitor for tumor recurrence.
Congrats to Claire Rabut, George Daghlian and collaborators!
www.biorxiv.org/content/10.1...

23.12.2024 16:51 — 👍 17    🔁 1    💬 1    📌 1
Schematic explaining In vivo tracking of active transcription. Injection of gene therapy is followed by measurement of the transcripts with RNA sensors, which produce a synthetic serum marker called RMA.

Schematic explaining In vivo tracking of active transcription. Injection of gene therapy is followed by measurement of the transcripts with RNA sensors, which produce a synthetic serum marker called RMA.

qPCR can measure expression of virtually any gene... in homogenized tissues. Here, we show an "in-vivo qPCR" equivalent, where we measure a sequence-specific transcript with synthetic serum markers and enzyme-based signal amplification.
www.biorxiv.org/content/10.1...

12.12.2024 16:51 — 👍 8    🔁 4    💬 0    📌 0
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What happens when you can take videos of acoustic proteins in 3D inside the body? 🧊 You can see things like the flow of CSF in the brain! 🧠
Congrats to Sunho Lee, co-senior author Claire Rabut, and colleagues on "Takoyaki" ultrasound. 🥟 #gasvesicles www.biorxiv.org/content/10.1...

18.11.2024 18:26 — 👍 36    🔁 8    💬 1    📌 1

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