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Dave Baker

@tweakyaustin.bsky.social

Engineer come bio-technologist running core Sequencing at the Quadram, UK.

263 Followers  |  542 Following  |  6 Posts  |  Joined: 15.11.2024
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Posts by Dave Baker (@tweakyaustin.bsky.social)

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Alessia Buscaino describing the evoluytion of commensalism and pathogenesis in Candida albicans and the potential role of RNAi #CMINorwich26 @quadraminstitute.bsky.social

04.03.2026 14:03 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
A photo of media in petri dishes being prepared with a quadrangle shape containing the text "Laboratory Support Technician, to provide a high standard of technical support to academic and research staff. Salary: Β£24,250 to Β£26,500, Contract length: indefinite, apply by 31 March 2026."

A photo of media in petri dishes being prepared with a quadrangle shape containing the text "Laboratory Support Technician, to provide a high standard of technical support to academic and research staff. Salary: Β£24,250 to Β£26,500, Contract length: indefinite, apply by 31 March 2026."

πŸ†• Vacancy! We’re looking for a Laboratory Support Technician to join our Science Operations team πŸ₯Ό

πŸ’· Β£24,250 to Β£26,500
πŸ—“οΈ Apply by 31 March 2026
➑️ buff.ly/tsGFmvC

04.03.2026 15:00 β€” πŸ‘ 3    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Microbiome stability in wild and rehabilitated insectivorous bats revealed by shotgun metagenomics www.biorxiv.org/content/10.6...

26.02.2026 09:45 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Advance notice: Will be de-rigging the cameras today as hedgehog corner is being revamped over the next few days. Taking out a raised bed and putting in a wildlife-friendly pond. We’ll still be feeding the hedgehogs (and one cat) but cameras will be offline.

12.02.2026 07:33 β€” πŸ‘ 11    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
A photo of the Quadram Institute with a quadrangle and the text "Group Leader, with a research focus on microbiome, modelling and host-microbe interactions."

A photo of the Quadram Institute with a quadrangle and the text "Group Leader, with a research focus on microbiome, modelling and host-microbe interactions."

⏰ Closing soon! We’re looking for an ambitious and collaborative Group Leader or Career Track Group Leader to pioneer the development of next-generation microbiome assays and model systems

πŸ’· Competitive
πŸ—“οΈ Apply by 15 February 2026
➑️ buff.ly/W3Sphca

12.02.2026 16:31 β€” πŸ‘ 3    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
A social card with the text, "Senior Research Scientist Microbiome Assay and Metaproteomics, to support with day-to-day running of the Figeys lab, including line management, overseeing budgets and scientific direction. Salary: Β£45,450 to Β£56,750, Contract length: 2 years, Apply by 15 February 2026."

A social card with the text, "Senior Research Scientist Microbiome Assay and Metaproteomics, to support with day-to-day running of the Figeys lab, including line management, overseeing budgets and scientific direction. Salary: Β£45,450 to Β£56,750, Contract length: 2 years, Apply by 15 February 2026."

⏰ Closing soon! We are looking for a Senior Research Scientist to support with day-to-day running of @dfigeys.bsky.social lab, including line management of staff, overseeing budgets, and leading the scientific direction.

πŸ’· Β£45,450 to Β£56,750
πŸ—“οΈ Apply by 15 February 2026
➑️ buff.ly/juVfDq7

10.02.2026 09:01 β€” πŸ‘ 2    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
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How’s your day going? My Saturday morning currently involves a game of escape and evasion from the resident tortoise, Carlos. He loves to have sex with my boots. Which is quite annoying.

07.02.2026 10:02 β€” πŸ‘ 58    πŸ” 2    πŸ’¬ 8    πŸ“Œ 1
A microscope image of candida and the Quadram logo with the text "Research Scientist (Bioinformatics), to work on the interplay between Candida albicans and gut bacterial adaptation, with a focus on RNA interference. Salary: Β£37,500 to Β£45,350, Contract length: 2 years. Apply by 8 February 2026"

A microscope image of candida and the Quadram logo with the text "Research Scientist (Bioinformatics), to work on the interplay between Candida albicans and gut bacterial adaptation, with a focus on RNA interference. Salary: Β£37,500 to Β£45,350, Contract length: 2 years. Apply by 8 February 2026"

⏰ Closing soon! We are looking for a Research Scientist (Bioinformatics) to join @buscainolab.bsky.social to work on the interplay between Candida albicans and gut bacterial adaptation, with a focus on RNA interference.

πŸ’· Β£37,500 to Β£45,350
πŸ—“οΈ Apply by 8 February 2026
➑️ buff.ly/EHV7N3I

04.02.2026 11:39 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Nice to see solid genetic tool development being published in Microbiology @microbiologysociety.org

'Improving a Tn7-based luciferase reporter system for promoter activity studies'

www.microbiologyresearch.org/content/jour...

28.01.2026 08:36 β€” πŸ‘ 13    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Oral bacteria play a role in chronic liver disease - Quadram Institute Dr Naiara Beraza contributed to a new study led by the Technical University of Munich (TUM) and King’s College London that has found strong evidence that bacteria from the mouth migrate to the gut in…

A new study published in the journal @natmicrobiol.nature.com shows that identical bacterial strains occur in both the mouth and gut of patients with advanced chronic liver disease and also reveals a mechanism by which oral bacteria affect gut health.

27.01.2026 10:01 β€” πŸ‘ 5    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

A New Cost Effective, Simplified Workflow for Transposon Insertion Sequencing (TIS)
doi.org/10.64898/202...

Large scale genomic rearrangements in selected Arabidopsis thaliana T-DNA lines are caused by T-DNA insertion mutagenesis
doi.org/10.1101/2021...

#Genomics #Bioinformatics

24.01.2026 04:48 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

A New Cost Effective, Simplified Workflow for Transposon Insertion Sequencing (TIS) https://www.biorxiv.org/content/10.64898/2026.01.23.699905v1

23.01.2026 23:34 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Social card advertising a vacancy that reads "Research Scientist. To create and use a transposon mutant library in Salmonella and build tools for transposon mutagenesis in higher organisms. Salary Β£37,500 to Β£45,350. Contract length 2 years. Apply by 28 January 2026.

Social card advertising a vacancy that reads "Research Scientist. To create and use a transposon mutant library in Salmonella and build tools for transposon mutagenesis in higher organisms. Salary Β£37,500 to Β£45,350. Contract length 2 years. Apply by 28 January 2026.

πŸ†• Vacancy! We are looking for a Research Scientist to join an exciting multipartner consortium in the END2AMR project to help develop novel antimicrobials using high throughput transposon mutagenesis.

πŸ’· Β£37,500 to Β£45,350
πŸ—“οΈ Apply by 28 January 2026
➑️ buff.ly/8iXH22u

16.01.2026 14:00 β€” πŸ‘ 3    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
A photo of the Quadram Institute building with the text "Group Leader, with a research focus on nutrition and microbiome-based interventions for the prevention and management of obesity. Salary: Competitive, Contract length: Indefinite, Apply by 18 January 2026."

A photo of the Quadram Institute building with the text "Group Leader, with a research focus on nutrition and microbiome-based interventions for the prevention and management of obesity. Salary: Competitive, Contract length: Indefinite, Apply by 18 January 2026."

⏰ Closing soon! We are looking for a Group Leader with a focus on nutrition and microbiome-based interventions for the prevention and management of obesity to join our Food, Microbiome and Health research programme as a Group Leader.

πŸ’· Competitive
πŸ—“οΈ Apply by 18 January 2026
➑️ buff.ly/5CIkq6J

11.01.2026 17:05 β€” πŸ‘ 5    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
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Need a winter warmer? Groundbreaking gene-edited tomato soup trial with higher levels of 'Sunshine' vitamin recruiting now - Quadram Institute Human trial of gene edited food, to understand whether biofortifying tomatoes in this way leads to higher levels of vitamin D in the blood

πŸ†• Our scientists and those @johninnescentre.bsky.social are launching one of the first human trials of gene edited food, to understand whether biofortifying tomatoes in this way leads to higher levels of vitamin D in the blood after people have eaten them πŸ…

23.09.2025 07:45 β€” πŸ‘ 16    πŸ” 10    πŸ’¬ 0    πŸ“Œ 1
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New book shares Quadram’s Best Practice in Microbiome Research - Quadram Institute Researchers from the Quadram Institute have developed an open access book to help ensure best practice in microbiome research.

The Best Practice in Microbiome Research presents protocols covering the design of ethical, inclusive studies, sample collection and genomic sequencing, bioinformatics processing of data and statistical analysis.

30.12.2025 09:00 β€” πŸ‘ 2    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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END2AMR launches to accelerate innovation against drug-resistant bacterial infections - Quadram Institute The Quadram Institute is part of END2AMR, a major new public-private research initiative designed to tackle some of the most difficult-to-treat bacterial infections

The END2AMR consortium will focus on chronic and drug-resistant infections caused by Gram-negative bacteria and Mycobacterium tuberculosis, which are responsible for significant global morbidity and mortality.

22.12.2025 11:01 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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What causes Candida infections? - Quadram Institute A new study will investigate Candida infections to understand how fungi adapt to the human gut and address the challenge of fungal infections

Supported by Β£2.7 million of funding from Wellcome’s Biology of Fungal Adaptation programme, a five-year research project leverages a network of leading international experts from the Quadram Institute, @dunnschool.bsky.social and @monashuniversity.bsky.social.

16.12.2025 09:00 β€” πŸ‘ 4    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
Vitamin D tomato growing in a greenhouse

Vitamin D tomato growing in a greenhouse

Be part of research at the Quadram Institute!

We’re running the ViTaL-D study to investigate whether @johninnescentre.bsky.social biofortified tomatoes developed through gene editing to be high in vitamin D leads to higher levels of active vitamin D in the blood πŸ…

➑️ buff.ly/gm0zYtx

14.12.2025 10:01 β€” πŸ‘ 12    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Congrats @efosternyarko.bsky.social and team for this great work building capacity for public health genomics to investigate cholera and other enteric bacteria, across Africa πŸ‘

www.lshtm.ac.uk/research/cen...

11.12.2025 07:54 β€” πŸ‘ 24    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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What causes Candida infections? - Quadram Institute A new study will investigate Candida infections to understand how fungi adapt to the human gut and address the challenge of fungal infections

πŸ†• New project uncovering the role of a molecular switch in Candida albicans infections.

Professor @buscainolab.bsky.social will lead a new study investigating how fungi adapt to life in the human gut, to address the growing global health challenge of fungal infections.

buff.ly/FGzNwWS

10.12.2025 12:11 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Congratulations to our Zimbabwean research collaborator Dr Tapfumanei Mashe for winning two awards at the 2025 Africa Health Excellence Awards in Durban, South Africa for Community Builder of the Year & Honorary Health Researcher of the Year.

Read more about our collaboration
➑️ buff.ly/4fJ87VQ

10.12.2025 10:53 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Course participant seated at computer in classroom setting. 

Text reads: Virtual course on Fungal Pathogen Genomics, 
Dates: 1-5 June 2026
The application deadline is 16 March 2026
Hosted by Wellcome Connecting Science.

Course participant seated at computer in classroom setting. Text reads: Virtual course on Fungal Pathogen Genomics, Dates: 1-5 June 2026 The application deadline is 16 March 2026 Hosted by Wellcome Connecting Science.

Strengthen your #fungal genome analysis using genomics tools and databases! #Fungal26

Join our experts online for Fungal Pathogen Genomics 2026.

πŸ—“οΈ Dates: 1-5 June 2026, UK time zone

Financial assistance is available πŸ’°
πŸ“© Apply by 16 March to be considered
πŸ“Ž bit.ly/4oucSxq

πŸ–₯️🧬🧫 #Genomics

08.12.2025 08:00 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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An action shot from tracking sanger lanes from late 90's!

05.12.2025 11:18 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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30 years ago to the day I walked into Norwich Research Park, UK. 6 years at @thesainsburylab.bsky.social then 8 years at @johninnescentre.bsky.social then 8 years at @earlhaminst.bsky.social, and finally @quadraminstitute.bsky.social where I am today. That’s a hell of a lot of DNA Sequencing!

05.12.2025 06:41 β€” πŸ‘ 18    πŸ” 1    πŸ’¬ 2    πŸ“Œ 1
PhD Out of order: investigating genetic and environmental drivers of genome rearrangement (LANGRIDGE_Q26DTP) 2026/27 | UEA PhD Out of order: investigating genetic and environmental drivers of genome rearrangement (LANGRIDGE_Q26DTP) 2026/27 | UEA

It's the last few days to apply for this #PhDposition starting in Oct 2026 in the @langridgelab.bsky.social @quadraminstitute.bsky.social.

Apply by 2 Dec if you have ever wondered what happens if bacteria follow the rules of life, but in a different order? πŸ€” this could be the project for you🦠🧬🧩

30.11.2025 22:02 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Prebiotics reverse effects of anti-depressants on the gut microbiome - Quadram Institute Scientists from the University of Ottawa and Beijing Institute of Lifeomics found that SSRIs, SNRIs and Tricyclic Antidepressants, commonly prescribed anti-depressants that target the…

"These findings reinforce the urgent need to understand how drugs and other xenobiotics affect the gut microbiome."

πŸ’¬ Our Director, Professor @dfigeys.bsky.social

26.11.2025 10:01 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Quadram joins world-class team to unlock secrets of antimicrobial resistance - Quadram Institute The project is being led by the University of Birmingham, and funded by the Biotechnology and Biological Sciences Research Council, through itsΒ Strategic Longer and Larger (sLoLa) grants scheme.…

β€œWe are hugely excited to be part of this award, which will deliver fundamental new knowledge about a super important aspect of bacterial biology.”
πŸ’¬ Professor @webberma.bsky.social

buff.ly/dpm22l5

25.11.2025 10:00 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Exciting day at London’s Science Museum for the #InnovationforGrowth meeting where we’re showing off AirSeq technology from @earlhaminst.bsky.social and @nhm.org

Meeting organised by @ukri.org to highlight the importance of research and innovation for economic growth.

24.11.2025 13:29 β€” πŸ‘ 11    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Researching the biology of bacterial biofilms to boost bioremediation - Quadram Institute Research into how the biofilms of Shewanella oneidensis and Geobacter sulfurreducens bacteria could help clean up metals from wastewater

πŸ†• Blog! This #BiofilmsWeek we catch up with Dr Heather Felgate to discover how studying the biofilms of Shewanella oneidensis and Geobacter sulfurreducens bacteria could help clean up metals from wastewater 🦠

buff.ly/q21zHkI

21.11.2025 09:15 β€” πŸ‘ 8    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1