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Dave Baker

@tweakyaustin.bsky.social

Engineer come bio-technologist running core Sequencing at the Quadram, UK.

235 Followers  |  490 Following  |  3 Posts  |  Joined: 15.11.2024  |  1.8023

Latest posts by tweakyaustin.bsky.social on Bluesky

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Exciting day at Londonโ€™s Science Museum for the #InnovationforGrowth meeting where weโ€™re showing off AirSeq technology from @earlhaminst.bsky.social and @nhm.org

Meeting organised by @ukri.org to highlight the importance of research and innovation for economic growth.

24.11.2025 13:29 โ€” ๐Ÿ‘ 8    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Researching the biology of bacterial biofilms to boost bioremediation - Quadram Institute Research into how the biofilms of Shewanella oneidensis and Geobacter sulfurreducens bacteria could help clean up metals from wastewater

๐Ÿ†• Blog! This #BiofilmsWeek we catch up with Dr Heather Felgate to discover how studying the biofilms of Shewanella oneidensis and Geobacter sulfurreducens bacteria could help clean up metals from wastewater ๐Ÿฆ 

buff.ly/q21zHkI

21.11.2025 09:15 โ€” ๐Ÿ‘ 7    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Quadram joins new initiative to develop liver disease models and reduce animal research - Quadram Institute Quadram is part of an innovative new project developing a liver disease model that will reduce reliance on animal testing

Dr Naiara Beraza will contribute expertise in the role of the microbiome as a regulatory mechanism of the gut-immune-liver axis during health and disease to the development of this immunocompetent gut-liver-adipose tissue model in healthy and MASLD conditions.

20.11.2025 18:03 โ€” ๐Ÿ‘ 4    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Science communicator Gabriel Astorga wins at the UK and Ireland TikTok Awards - Quadram Institute Gab Astorga, a social media creator and Quadram Institute microbiologist secured the top-spot in the Books and Learning category at the TikTok Awards UK & Ireland 2025. Now in its second year, theโ€ฆ

๐Ÿ†• @gabastorga.bsky.social , a social media creator and Quadram Institute microbiologist secured the top-spot in the Books and Learning category at the TikTok Awards UK & Ireland 2025 โœจ

17.11.2025 15:15 โ€” ๐Ÿ‘ 6    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
A photo of organ on chip technology with the text "Research Scientist, to establish gut-brain/gut-CNS microfluidic chip systems. Salary: 27 months, Apply by 28 November 2025"

A photo of organ on chip technology with the text "Research Scientist, to establish gut-brain/gut-CNS microfluidic chip systems. Salary: 27 months, Apply by 28 November 2025"

๐Ÿ†• Vacancy! Weโ€™re looking for a Research Scientist to establish gut-brain/gut-CNS microfluidic chip systems to enable the study of the role of microbial products in regulating gut-immune-CNS communication ๐Ÿ”ฌ

๐Ÿ’ท ยฃ37,500 to ยฃ45,350
๐Ÿ—“๏ธ Apply by 28 November 2025
โžก๏ธ buff.ly/vjp98fx

14.11.2025 11:00 โ€” ๐Ÿ‘ 4    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Rethinking Omega-3s for Health and Sustainability ยซ Nutrition# ยซ Cambridge Core Blog The paper โ€œSustainable and available sources of omega-3 fatty acids for health: are the current dietary recommendations, food sources and legislation fit for purpose?โ€œ, published in Nutritionโ€ฆ

๐Ÿ“ฐ A paper our Group Leader Dr Maria Traka contributed to "Rethinking Omega-3s for Health and Sustainability" is the @nutritionsociety.bsky.social 's paper of the month โคต๏ธ

14.11.2025 15:30 โ€” ๐Ÿ‘ 5    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A social card with an illustration of DNA and the text "Research Scientist, to develop new experimental methods to better understand horizontal gene transfer in the gut microbiome, salary: ยฃ37,500 to ยฃ43,350, Contract length: 2 years, Apply by 30 November 2025."

A social card with an illustration of DNA and the text "Research Scientist, to develop new experimental methods to better understand horizontal gene transfer in the gut microbiome, salary: ยฃ37,500 to ยฃ43,350, Contract length: 2 years, Apply by 30 November 2025."

๐Ÿ†• Vacancy! Weโ€™re looking for a Research Scientist to join the Laboratory of Dr Chris Quince based at the Quadram Institute and @earlhaminst.bsky.social in the Food, Microbiome and Health programme ๐Ÿ”ฌ

๐Ÿ’ท ยฃ37,500 to ยฃ45,350
๐Ÿ—“๏ธ Apply by 30 November 2025
โžก๏ธ buff.ly/E19Nd83

15.11.2025 10:00 โ€” ๐Ÿ‘ 2    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Quadram joins new initiative to develop liver disease models and reduce animal research - Quadram Institute Quadram is part of an innovative new project developing a liver disease model that will reduce reliance on animal testing

๐Ÿ†• Dr Naiara Beraza from the Quadram Institute is part of an innovative new project developing an interconnected multi-organ platform that replicates non-alcoholic fatty liver disease.
buff.ly/COe7FvU

11.11.2025 15:41 โ€” ๐Ÿ‘ 5    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿš€ Weโ€™re delighted to share that OriColโ„ข, manufactured by TOGL, has achieved CE marking under EU MDR (2017/745)!
This milestone reflects compliance with the EUโ€™s rigorous standards for safety, performance and quality.
#CEmark #MedTech #Innovation #Oricol

07.11.2025 09:35 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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From kitchen to infection; The hidden story of Campylobacter in our kitchens - Quadram Institute Dr Bilal Djeghout explains how he's developed a new kitchen model experiment to study in the lab how Campylobacter spreads in the kitchen

"My experiments show that Campylobacter can survive on cutting boards longer than expected, even though it is normally sensitive to oxygen."๐Ÿฆ 

๐Ÿ’ฌ Dr Bilal Djeghout

05.11.2025 15:02 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Ben Goldsborough MP talks to NNUH Consultant Dr Emma Webb

Ben Goldsborough MP talks to NNUH Consultant Dr Emma Webb

Dr Laura Bardon, Andrew Stronach, Dr Emma Webb, Dr Maria Traka and Professor Martin Warren in Parliament

Dr Laura Bardon, Andrew Stronach, Dr Emma Webb, Dr Maria Traka and Professor Martin Warren in Parliament

Professor Martin Warren talks to Adrian Ramsey MP

Professor Martin Warren talks to Adrian Ramsey MP

Dr Laura Bardon and Dr Emma Webb talk to Melissa Haynes Agoro

Dr Laura Bardon and Dr Emma Webb talk to Melissa Haynes Agoro

Our researchers are in Parliament today for @senseaboutsci.bsky.social's #EvidenceWeek talking to policymakers about hidden hunger in the UK ๐Ÿ—ฃ๏ธ

Read more about hidden hunger and our work to tackle it
โžก๏ธ buff.ly/AUt91By

04.11.2025 12:00 โ€” ๐Ÿ‘ 7    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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From kitchen to infection; The hidden story of Campylobacter in our kitchens - Quadram Institute Dr Bilal Djeghout explains how he's developed a new kitchen model experiment to study in the lab how Campylobacter spreads in the kitchen

๐Ÿ†• Blog! Dr Bilal Djeghout explains how he's developed a new kitchen model experiment to study in the lab how Campylobacter spreads in the kitchen ๐Ÿด
buff.ly/Jjp6bXX

31.10.2025 09:32 โ€” ๐Ÿ‘ 5    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A photo of fermented pickles with the text "Research Scientist (Fermented Foods and Nutrition) to join the FlavourFerm project and explore the nutrition of fermented foods, Salary: ยฃ37,500 to ยฃ45,350, Contract length: 2 years, Apply by 6 November 2025"

A photo of fermented pickles with the text "Research Scientist (Fermented Foods and Nutrition) to join the FlavourFerm project and explore the nutrition of fermented foods, Salary: ยฃ37,500 to ยฃ45,350, Contract length: 2 years, Apply by 6 November 2025"

Are you passionate about nutrition science and the potential of #fermentedfoods to transform plant-based diets?

Check out our current vacancy โคต๏ธ

๐Ÿ’ท ยฃ37,500 to ยฃ45,350
๐Ÿ—“๏ธ Apply by 6 November 2025
โžก๏ธ buff.ly/dxPkRXz

28.10.2025 16:15 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Interestingly, #drugs for the nervous system (antidepressants/antipsychotics) stand out: #SSRI/ #SNRI/ #TCA push the gut #microbiome into alternate states, lowering functional redundancy(lower capacity to respond) and ramping up antimicrobial-resistance proteins.
@quadraminstitute.bsky.social

27.10.2025 07:32 โ€” ๐Ÿ‘ 6    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A landscape shot of the rooftops of Norwich, with the Cathedral in the centre. In the foreground are trees without their leaves.

A landscape shot of the rooftops of Norwich, with the Cathedral in the centre. In the foreground are trees without their leaves.

1 in 5 people in the UK are estimated to be deficient in #vitaminD during winter and spring ๐Ÿ“‰

Our ViTaL-D Study aims to understand whether tomatoes biofortified through gene-editing tomatoes to be high in vitamin D leads to higher levels of active vitamin D in the blood ๐Ÿ…

โžก๏ธ buff.ly/SIsELo6

26.10.2025 16:03 โ€” ๐Ÿ‘ 9    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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@enriquetagarcia.bsky.social thanks for hosting me this week! Implemented low cost custom full length 16S V1-9 on @nanoporetech.com

22.10.2025 08:59 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Linking antimicrobial resistance, climate warming, and carbon use efficiency in Arctic soils (HERNANDEZ-GARCIA_UEA_ARIES26) at University of East Anglia on FindAPhD.com PhD Project - Linking antimicrobial resistance, climate warming, and carbon use efficiency in Arctic soils (HERNANDEZ-GARCIA_UEA_ARIES26) at University of East Anglia, listed on FindAPhD.com

PhD opportunity to work in my lab at UEA, together with @drbradbrad.bsky.social and Marc Dumont โ€œLinking AMR, global warming and CUE in deglaciated soilsโ€

www.findaphd.com/phds/project...

07.10.2025 06:02 โ€” ๐Ÿ‘ 12    ๐Ÿ” 14    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Element Biosciences Sues Illumina Alleging Anticompetitive Behavior, Patent Infringement Element has filed two lawsuits in the US and one in Germany, escalating the ongoing legal battle between the two sequencing technology firms.

www.genomeweb.com/sequencing/e... Element Bio sues Illumina

23.09.2025 05:39 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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New ยฃ644K Microbiome Innovation Network to drive UK Bioscience Research and impact health, food, and environments - Quadram Institute The Microbiome Innovation Centre at the University of Liverpool, the National Biofilms Innovation Centre, the Quadram Institute, Nottingham Trent University, and the University of Oxford have beenโ€ฆ

๐Ÿ†• New ยฃ644K Microbiome Innovation Network to drive UK Bioscience Research and impact health, food and environments.

15.09.2025 14:00 โ€” ๐Ÿ‘ 10    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

If you are UK-based and working on any aspect of microbiomes (human, plant, insect, soil, animal, ...), please do sign up to Microbiome-Net for details of networking, funding and training opportunities.

forms.office.com/pages/respon...

13.09.2025 06:31 โ€” ๐Ÿ‘ 34    ๐Ÿ” 39    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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New blog post โ€“ A quick look at Roche's SBX
lh3.github.io/2025/09/11/a...

12.09.2025 03:26 โ€” ๐Ÿ‘ 57    ๐Ÿ” 30    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3
Photo of the Quadram Institute football team wearing their branded, green football kits. The goalkeeper stands to the  side wearing a yellow and black top.

Photo of the Quadram Institute football team wearing their branded, green football kits. The goalkeeper stands to the side wearing a yellow and black top.

Quadram Institute football team captain, Emad, shows off his footwork.

Quadram Institute football team captain, Emad, shows off his footwork.

Four Quadram Institute football team members in action on the field.

Four Quadram Institute football team members in action on the field.

The Quadram Institute football team has a team huddle on the field.

The Quadram Institute football team has a team huddle on the field.

Our Quadram Institute football team scored an impressive 26 goals at the annual Norwich Research Park 5-a-side tournament โšฝ

The team came 4th out of 7, facing tough opposition against @thesainsburylab.bsky.social, @earlhaminst.bsky.social and @uniofeastanglia.bsky.social ๐Ÿฅ‰

๐Ÿ“ท Jacob Dehinsilu

05.09.2025 09:01 โ€” ๐Ÿ‘ 8    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Dave Baker shows a visiting group the sequencing facility at the Quadram Institute

Dave Baker shows a visiting group the sequencing facility at the Quadram Institute

We were delighted to welcome board members and visitors from the Norfolk and Waveney University Hospitals Group today ๐Ÿฅ

We're excited to work with NHS partners to strengthen clinical research and innovation for the communities we serve.

Read more about our work
โžก๏ธ buff.ly/BeS0Loc

05.09.2025 13:00 โ€” ๐Ÿ‘ 5    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐ŸŽ‰ Another milestone for Origin Sciences! Weโ€™ve opened our new clinical suite at Hollinswood House, Telford, to support our ยฃ1m #TRIOMIC study in partnership with SaTH. Over the next year 6,000 symptomatic patients will help us advance #ColorectalCancer screening and improved patient pathways!

04.07.2025 10:29 โ€” ๐Ÿ‘ 3    ๐Ÿ” 3    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

๐ŸŽ‰ Ellele Health turns ONE! ๐ŸŽ‰

In just 12 months, we:
โœ… Gained UKCA mark for sampling device
๐Ÿ“„ Published joint HPV testing whitepaper
๐Ÿ“ˆ Ran Ellele01 study
๐Ÿ“… Planned new gynae cancer detection study
๐Ÿ’ก Were selected for Lynch syndrome testing study
โค๏ธ Built a kick-ass team!
& weโ€™re just getting started!

16.07.2025 10:20 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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โ˜€๏ธ Summer Party at Darwin College โ˜€๏ธ
Yesterday we came together to celebrate progress, connect beyond remote working & our growing teams, and enjoy a BBQ + punting ๐Ÿšค

Even better, a major milestone in our research into cancer diagnostics was confirmed โ€” more on that soon!๐Ÿฅ‚

#CancerResearch #Teamwork

20.08.2025 12:11 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Genome-wide screening using TraDIS accelerates identification of key adaptive mutations of longer-term evolution experiment in Escherichia coli. https://www.biorxiv.org/content/10.1101/2025.09.02.673662v1

03.09.2025 06:16 โ€” ๐Ÿ‘ 6    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Home

๐Ÿšจ Abstract submissions for CampyUK 2025 are now open! Join us in Oxford (24โ€“25 Sept) to explore the latest in Campylobacter research.

๐Ÿ—“ Deadline: 31 July

๐Ÿ”— campyuk.web.ox.ac.uk/home
#CampyUK2025 #Microbiology #AMR #OneHealth

13.05.2025 12:02 โ€” ๐Ÿ‘ 3    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Fabulous kick off talk at #GenomeScience25 from @matthewcobb.bsky.social discussing just a few of Francis Crickโ€™s great conceptual leaps (and some less stellar moments) in the understanding of molecular biology and evolution as outlined in his new biography: get it on the Xmas list amzn.eu/d/fIPxARk

09.07.2025 13:49 โ€” ๐Ÿ‘ 44    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Evidence supporting the first secondary chromosome in actinobacteria as a hallmark of the Embleya genus Embleya is a genus within the family Streptomycetaceae, a group of actinobacteria with outstanding capacity for production of specialised metabolites and a strikingly complex life cycle. In this work, we sequenced the complete genome of the new species Embleya australiensis MST-11070 and validated the assembly using optical mapping. The genome of E. australiensis MST-11070 consists of a 7.1 Mb linear chromosome and three additional replicons, including a 4.2 Mb linear replicon, EEC1, significantly larger than all previously described secondary replicons from bacteria. EEC1 is typified by its similar composition to the chromosome in terms of GC-content, codon usage and gene functions. It also carries terminal inverted repeats identical to the chromosome. EEC1 is enriched in biosynthetic gene clusters (BGCs), including the only copy of the BGCs for the spore pigment and the surfactant peptide SapB, metabolites essential for the organism's lifecycle. EEC1 contains an origin of replication with at least some chromosomal properties, and its replication is likely to depend on functions provided by chromosomally located genes. Further comparison of Embleya spp. genomes suggests that EEC1-like replicons are conserved across the genus, in contrast to other known large linear extrachromosomal replicons (megaplasmids) in the order. EEC1 is thus a hallmark of the Embleya genus and is central to its evolution within the Streptomycetaceae family. We propose EEC1 as a secondary chromosome, distinct from previously described secondary chromosomes that utilise plasmid-like replication mechanisms (chromids) and the largest secondary replicon reported in bacteria, to date. ### Competing Interest Statement Ernest Lacey is a Founder, Board Member, and the Managing Director of Microbial Screening Technology Pty. Ltd. The authors declare no competing financial interests. Biotechnology and Biological Sciences Research Council, https://ror.org/00cwqg982, BB/P021506/1, BBS/E/J/000PR9790, BB/X01097X/1, BB/M011216/1 Novo Nordisk Foundation, https://ror.org/04txyc737, NNF22OC0078997

Our new preprint is out! EEC1 is a massive 4.2 Mb secondary chromosome from Embleya australiensis. Conserved across Embleya, these are the first replicons of their kind in Actinobacteria and the largest secondary replicons in bacteria identified to-date!

1/6 ๐Ÿฆ ๐Ÿงช๐Ÿงฌ๐Ÿ”ฌ

www.biorxiv.org/content/10.1...

09.07.2025 11:56 โ€” ๐Ÿ‘ 27    ๐Ÿ” 12    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 1

@tweakyaustin is following 20 prominent accounts