Prof Paula Salgado

I’ll try it next week as did something similar on Thursday night as Friday was fully booked and it was definitely useful.

This week I went back to being student - and it was great! Fantastic to attend #cryoEM course at eBIC, co-organised with @astburycentre.bsky.social! I learned a lot and also realised my #proteincrystallography expertise are useful here too ;) can’t wait to apply what I learned!

Not everywhere. It’s up to the teachers and head teachers to change it back to be about books, reading and the joy a good story brings. #WBDisaboutreading

Our son’s school doesn’t do dress up. They have a storytelling evening with teachers reading stories for kids and a book fair. And usually a reading-related activity like making bookmarks in class. A brilliant approach IMHO! #WBDisaboutreading

🧵 UKRI has changed their budgets from considering by disciplines (as bounded by Research Council remits) to by buckets. The inability to see the magnitude of change to disciplinary funding over the spending review period is creating uncertainty.

Cartas com Ciência Associação sem fins lucrativos que visa combater desigualdades sociais através da ciência, desenvolvendo e implementando programas de troca de cartas entre cientistas e estudantes em língua portuguesa...

Hoje escrevi uma carta, parte do programa #cartascomciencia. 1o recebi umaa carta de alunas do 11o ano, curiosas sobre ciencia e investigacao. Depois, foi a minha vez de "pegar na caneta"
Recomendo a todos os cientistas lusófonos: participem!

www.cartascomciencia.org

Ohh.... #biology #lego

Today is a landmark in the #Salgadolab as Dr Anna Barwinska-Sendra moves on to new adventures. Here’s to your success, I’ll be cheering and supporting you! Thanks for your amazing work, inspiring ideas and unwavering support! This partnership will continue in new ways!🥂

Hey #Microsky, time to celebrate your amazing female colleagues, students and mentors for #IWD2026! Nominate an inspiring woman whose research, teaching, innovation, or community leadership deserves recognition! @femsmicro.org crm.fems-microbiology.org/ssp/internat...

💡 We are inviting you to nominate a woman in microbiology whose work or impact deserves to be seen.

Selected nominations will be featured on the FEMS website and across our social media channels on International Women’s Day, 8 March.

👉 Who inspires you? Nominate them by 4 March . buff.ly/AKyMbQD

The UKRI grants pause risks forcing out mid-career medical researchers The fact that a mere few months’ hiatus imperils the futures of those without permanent posts underlines the fragility of UK biomedicine, says a researcher

Opinion: When a mere few months’ hiatus in UKRI funding opportunities imperils the futures of those without permanent posts, it only underlines the fragility of UK biomedicine, says a researcher #AcademicSky #Research
ow.ly/q32l50Yhv9m

#HappyLunarNewYear to all who celebrate it!

UKRI CEO updates the research community on areas of uncertainty Following an open letter of 1 February, Sir Ian Chapman responds to feedback and provides an update.

Another update from #UKRI CEO on #UKsciencefunding #UKRI
www.ukri.org/news/ukri-ce...

No new information and fails to address/explain the severe funding rate cuts taking place at MRC for the round currently under review (Sept2025). That's 2025/26 budget so should *not* be affected by SR.

It's International Day of Women & Girls in Science and I spoke to Emily Warner at The Pharmacist about the importance of supporting and championing more women and girls into Science, Technology, Engineering and Mathematics.

UKRI funding changes ‘pushing junior researchers abroad’ - Research Professional News Disruptions to core funding streams raise fears for a “generation” of early career researchers

NEW on RPN:

Hits to research grant funding at UKRI are already causing junior researchers to leave the country, according to some academics, amid fears that those at the start of their careers are set to be “disproportionately” impacted. #ECRchat

www.researchprofessionalnews.com/rr-news-uk-r...

To celebrate #IDWGS2026, we're highlighting women who shaped microbiology but never got their flowers, starting with Fanny Hesse.

We're not stopping there; help us continue the work. Nominate a female microbiologist you know for a feature on our blog: buff.ly/kk7Ieye

#IDWGS #WomenInSTEM

To all Women and Girls in Science: congratulations! It's a testament to you and your work that you are here, as odds are still stacked against us.
Celebrating achievements but recognising improvement is still needed! Happy International Day of Women & Girls in Science #WomeninScience2026 #IDWGS2026

Preprint on the permeability of Gram+ bacterial cell wall from a few months ago. Intriguing findings, elegant methodology. Cell wall is largely impermeable to molecule sizes of mNeonGreen (27kDa) and above. How do larger secreted proteins get through? www.biorxiv.org/content/10.1... #microsky

The emergence and biological characteristics of linezolid-resistant Clostridioides difficile isolates in the Asia-Pacific Region Linezolid-resistant Clostridioides difficile, conferred by the acquisition of cfr-like genes, has been reported in Europe and America. However, the emergence of linezolid resistance in C. difficile...

The emergence and biological characteristics of linezolid-resistant Clostridioides difficile isolates in the Asia-Pacific Region www.tandfonline.com/doi/full/10....

We don't necessarily want to stop aggregation as this is sometimes a feature of the mutations introduced. But preventing aggregates from sticking to the bottom and give high OD would help, I hope.

That's interesting 🤔 Always intriguing when microbes do counter-intuitive things 😀
We can't use Triton-X as would alter what we're trying to analyse. Biofilm formation itself is a read out of some of the mutations, but would be good if we can prevent it from sticking to the bottom!

That looks very neat, but lacks the high throughput that microplates allow. Do you know if they’re planning to expand it to a multi-well format?

Ok, thanks for the details! I think we spikes when we move the stratus in the anaerobic chamber, but haven't tired with the holder yet. Wanting to hear how others find it before committing to buying one ;)

Thanks, Matt! Do you use Cerillo's shaker or a normal one + their adapter? Any details are much appreciated :)

🌟 Applications are now open for the Next Generation of AI Chemists Programme, a funded opportunity for penultimate-year undergraduates from backgrounds under-represented in chemistry.

📍 Imperial London | 📅 6–7 July 2026 (in person)
👉 Apply here: buff.ly/MLfs9Zg

Please repost if you’re in the area of #AI or #chemistry. Funded by EPSRC. #chemsky

For some of our C. difficile mutant strains, we get lots of biofilm formation and I was wondering if shaking might help. But of course, that's only if we can still get consistent OD measurements with no false spikes due to the shaking.

Thanks! I would say that is naive or just wishful thinking. Or not really understanding what only ~12 biomedical research being funded in a 12 month period means for the whole ecosystem.

Did anyone ask if they understand that lower funding rates and a very long pause will mean much reduced capacity for biomedical research once that funding resumes? Loss of staff, knowledge, impact on small/medium biotech and other industry that all supports the "Life Science priority"?