Taras Pogorelov's Avatar

Taras Pogorelov

@taraspogorelov.bsky.social

Theoretical & computational biophysics. Molecular information transfer in the cell. In-cell signaling, protein, membrane & lipid dynamics. Complex environments. Lab @UIUC: pogorelov.scs.illinois.edu

868 Followers  |  1,295 Following  |  39 Posts  |  Joined: 17.11.2024
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Posts by Taras Pogorelov (@taraspogorelov.bsky.social)

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A picture is worth a thousand words or, in this case, billions of calculations.

With help from @ncsaatillinois.bsky.social, Drs. Emad Tajkhorshid, Hale Şiir Hasdemir, and PhD candidates Yupeng Li and Carlos Cuellar revealed how membrane transport proteins in E. coli function.

(Story link in bio)

24.02.2026 17:23 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
A photo of Lynmarie Thompson, the current president of the Biophysical Society, presenting plaques to Ilya Levental and Ariane Briegel, the Program Chairs of the 2026 Annual BPS Meeting

A photo of Lynmarie Thompson, the current president of the Biophysical Society, presenting plaques to Ilya Levental and Ariane Briegel, the Program Chairs of the 2026 Annual BPS Meeting

Thank you Lynmarie Thompson, @leventallab.bsky.social and
@arianebriegel.bsky.social for your service to the @biophysicalsoc.bsky.social and in organizing the 2026 BPS Meeting!

24.02.2026 05:26 β€” πŸ‘ 11    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0

Sad to miss my first Biophysical Society Meeting in 12 years, but the lab will have strong representation! A thread (1/7)

22.02.2026 17:48 β€” πŸ‘ 11    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0
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Attending #bps2026? Check out these exciting events hosted by CPOW:

PI to PI Mixer
Sunday 4-6 PM
Esplanade 159/160

Steps and Suggestions for Getting Your Scientific Paper Published
Monday 2:30-4 PM
Esplanade 155

Looking forward to seeing you all in San Francisco!

@biophysicalsoc.bsky.social

16.02.2026 13:17 β€” πŸ‘ 12    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1
Cutaway and close-up views of a Martini coarse-grained whole-cell model of JCVI-syn3A, showing the densely packed cytoplasm with proteins, RNA, metabolites, and chromosome inside a lipid membrane with embedded membrane proteins

Cutaway and close-up views of a Martini coarse-grained whole-cell model of JCVI-syn3A, showing the densely packed cytoplasm with proteins, RNA, metabolites, and chromosome inside a lipid membrane with embedded membrane proteins

Our paper on [Bentopy](doi.org/10.1002/pro....) is out in Protein Science! We developed Bentopy to make assembling large-scale MD models more accessible, building on what we learned from trying to simulate whole-cell models. Here's our updated Martini JCVI-syn3A cell modelπŸ‘‡

13.02.2026 15:37 β€” πŸ‘ 32    πŸ” 17    πŸ’¬ 1    πŸ“Œ 0
Model of mitochondrial compartments. The assembly of the mitochondrial model based on an experimentally informed membrane structure (white), from an empty structure (left) into a mask representation of the IMS (yellow) and matrix (pink) compartments represented by 3 nm voxels. Structures are packed into their assigned compartments based on the mask. In the last section and the magnified inset, structures are colored by kind: Proteins (green), RNA (dark blue), metabolites (pale blue).

Model of mitochondrial compartments. The assembly of the mitochondrial model based on an experimentally informed membrane structure (white), from an empty structure (left) into a mask representation of the IMS (yellow) and matrix (pink) compartments represented by 3 nm voxels. Structures are packed into their assigned compartments based on the mask. In the last section and the magnified inset, structures are colored by kind: Proteins (green), RNA (dark blue), metabolites (pale blue).

Our paper about Bentopy is now published in Protein Science!

Bentopy makes assembling large-scale MD models accessible and fast.

doi.org/10.1002/pro....

@janstevens.bsky.social, @cg-martini.bsky.social

13.02.2026 15:07 β€” πŸ‘ 13    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1

Pleased to share the final version of this behemoth of a paper, now finally published. I guess I can retire now?
www.nature.com/articles/s41...

More functional data, many thousands of words removed, and a few other updates from last year's preprint.

12.02.2026 11:22 β€” πŸ‘ 125    πŸ” 51    πŸ’¬ 7    πŸ“Œ 4
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Don’t miss this morning’s NITMB Seminar!

@karthikshekhar.bsky.social, the John F. Heil Jr Assistant Professor at @ucberkeleyofficial.bsky.social, shares insights into bioelectrical dynamics at membrane interfaces

Join the seminar online or in-person at NITMB www.nitmb.org/nitmb-semina...

16.01.2026 14:01 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Sharing a PhD advert on a very cool project on cells interacting with bacteria, which is offered by a colleague from our institute!

15.01.2026 09:51 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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A dynamic displacement mechanism drives protein import into mitochondria Most mitochondrial proteins are produced in the cytosol and imported through the translocase of the outer mitochondrial membrane (TOM) to reach their final destination. Although this protein entry gat...

πŸ“’ New preprint alert!
How do proteins enter mitochondria? We uncovered a surprising mechanism at the mitochondrial entry gateβ€”using #NMR, in vivo single-particle tracking, yeast experiments, and MD simulations to crack the code.
www.biorxiv.org/content/10.6...
#StructuralBiology #Mitochondria
🧡 1/8

14.01.2026 19:16 β€” πŸ‘ 39    πŸ” 21    πŸ’¬ 2    πŸ“Œ 0

Monday,Β  19th of January at 11:30,
Manish Kushwaha from Micalis Institute, INRAE, Jouy-en-Josas.

**Β  Bacteriophages as Communication Signals: Information Processing in Multicellular Bacterial Systems **

This seminar will take place at the seminar room of Gulliver C1.62Β  at 11:30.

14.01.2026 17:03 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
copyright Palina Nepachalovich of ZML Dresden

copyright Palina Nepachalovich of ZML Dresden

Ups we did it again! Please mark your calender. EMBO Workshop β€œLipid Code to Life”, taking place September 7–11, 2026, in Dresden, organized by Maria Fedorova, @lipid.bsky.social, Valerie O'Donnell, @holthuislab.bsky.social and @molcellbiophys-lab.bsky.social πŸ₯³ Retweets = lipidlove

15.12.2025 14:36 β€” πŸ‘ 44    πŸ” 37    πŸ’¬ 1    πŸ“Œ 1

Really cool work from Eugene’s group. I got to hear about it straight from the source at the protein folding dynamics conference this week!

09.01.2026 08:55 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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MemPrO: A Predictive Tool for Membrane Protein Orientation Membrane proteins play a vital role in numerous cellular processes, including ion transport, intercellular communication, and antibiotic resistance. Ensuring their accurate orientation within lipid bi...

🌟 New Tool Alert!

We present MemPrO – a toolkit for orienting and building membrane protein systems:
β€¨βœ… Membrane protein orientation β€¨βœ… Mixed membrane building β€¨βœ… Double membranes & curvature β€¨βœ… Peptidoglycan cell wall support

πŸ”— github.com/pstansfeld/mempro β€¨πŸ“– pubs.acs.org/doi/10.1021/...

25.12.2025 22:03 β€” πŸ‘ 48    πŸ” 13    πŸ’¬ 0    πŸ“Œ 0

Opportunity: postdoctoral fellowships at the center for Quantitative Cell Biology (QCB), Univ. of Illinois, in close collaboration with our group. Your ticket to become an expert in whole-cell Martini simulations !
qcb.illinois.edu/postdoctoral...

22.12.2025 10:27 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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The Bryson Lab | Vaccine Development & Research at MIT Developing effective accessible vaccines to end tuberculosis worldwide. Combining immunoengineering, molecular microbiology & systems biology at MIT.

Two pieces of fun news:

1. We've launched a new website for our lab: www.brysonlab.org

2. With some new funding, we are recruiting for new postdocs and graduate students. The projects build upon our previous studies of antigen presentation and phagosome biology and go into new exciting dimensions!

18.12.2025 18:29 β€” πŸ‘ 41    πŸ” 25    πŸ’¬ 2    πŸ“Œ 4
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New on the Martini webportal (cgmartini.nl/docs/contact...): acknowledgment of all the people who contribute to the development. The list is still growing - if you feel your name should be added please let us know.

18.12.2025 09:41 β€” πŸ‘ 11    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Calling all archaeal enthusiasts! πŸ”¬πŸ”₯ From molecular machines to microbial communities, Archaea never fail to surprise us!
We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK!
Sign up here: meetings.embo.org/event/26-arc...
#ArchaeaSky

16.12.2025 14:18 β€” πŸ‘ 42    πŸ” 27    πŸ’¬ 2    πŸ“Œ 1
University of Florida - Details - AST/ASO/FULL PROF in Artificial Intelligence for Quantum Chemistry

#chemjobs Come be my colleague in 2026 ! New position in the Department of Chemistry at the University of Florida. AST/ASO/FULL PROF in Artificial Intelligence for Quantum Chemistry.

explore.jobs.ufl.edu/en-us/job/53...

16.12.2025 00:42 β€” πŸ‘ 10    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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Join 2026 BPS Lecturer Lewis Kay on Tuesday, February 24, 2:00 PM - 3:00 PM at #bps2026 for an informal and inspiring discussion. Dr. Kay will share insights from his scientific careerβ€”from pioneering discoveries to lessons learned along the wayβ€”and reflect on how the field continues to evolve.

15.12.2025 19:21 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
Lead a lab at Janelia

Pioneer next-generation tools for biological discovery

Apply by Feb. 3, 2026
janelia.org/groupleader

Lead a lab at Janelia Pioneer next-generation tools for biological discovery Apply by Feb. 3, 2026 janelia.org/groupleader

Apply by Feb. 3 to join HHMI's Janelia Research Campus as a Group Leader!

Group Leaders drive breakthroughs & experimental approaches in imaging, molecular engineering, protein chemistry, mass spectrometry, & methods that don't yet exist. Learn more: janelia.org/groupleader πŸ§ͺ

15.12.2025 18:15 β€” πŸ‘ 8    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
Picture of a screen with a powerpoint slide showing a picture of me and the following text "Inaugural Lecture, Fiona Kearns, "Emerging Opportunities in Biophysics: Glycoprotein Characterization by Simulations" 17:15, 15.21.2025, HS Chemie

Picture of a screen with a powerpoint slide showing a picture of me and the following text "Inaugural Lecture, Fiona Kearns, "Emerging Opportunities in Biophysics: Glycoprotein Characterization by Simulations" 17:15, 15.21.2025, HS Chemie

🚨 Are you into comp chem/biophys? Do you like glycobiology? Are you located around Freiburg Germany? Do you like me as a person? Want to see an open lecture about Computational Glycobiology/Biophysics in Freiburg, Germany, delivered by me?!

15 Dec, 17:15 HS Chemie @ Alberstrasse 21, 79104 Freiburg

10.12.2025 13:34 β€” πŸ‘ 23    πŸ” 6    πŸ’¬ 3    πŸ“Œ 3
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The Gonzalez Lab at Columbia University is seeking a scientific leader!

Join us in a Research Scientist position, driving single-molecule, structural, and biochemical studies of translation, translational control, and other RNA-based processes.

Apply: apply.interfolio.com/176949

10.12.2025 12:15 β€” πŸ‘ 12    πŸ” 18    πŸ’¬ 0    πŸ“Œ 0
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Tenure Track Professorship (W1 with Tenure Track to W3) in β€œMolecular Biology" (f/m/d) - Heidelberg job with UniversitΓ€t Heidelberg | 12850668 The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a Β  Tenure Track Professors...

We are recruiting a tenure track professor in the broader area of molecular biology @zmbh.uni-heidelberg.de at Heidelberg University! www.nature.com/naturecareer... Please share and apply!

09.12.2025 18:11 β€” πŸ‘ 69    πŸ” 58    πŸ’¬ 0    πŸ“Œ 1
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Our review on Integrative modelling of biomolecular dynamics πŸ’ƒ is now live at COSB

We discuss approaches to integrate computational methods with time-dependent & time-resolved experiments to study protein dynamics

With @dariagusew.bsky.social & Carl G. Henning Hansen
doi.org/10.1016/j.sb...

09.12.2025 22:13 β€” πŸ‘ 56    πŸ” 20    πŸ’¬ 1    πŸ“Œ 0
BPS2026 Student Volunteers | Biophysical Society The Biophysical Society invites undergraduate and graduate students to volunteer time (6 hours) at the Annual Meeting in exchange for complimentary meeting registration.Β  Volunteers must be members…

Students! BPS offers volunteer opportunities at the Annual Meeting in exchange for complimentary meeting registration. Learn more and apply: www.biophysics.org/2026meeting/...

08.12.2025 20:24 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Discovering Glycosylation-Dependent Protein Function by Thermal Proteome Profiling Protein glycosylation regulates essential cellular processes including protein folding, stability, and cell-cell interactions; however, how aberrant glycosylation impacts protein function and interact...

Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale πŸ‘

www.biorxiv.org/content/10.6...

08.12.2025 02:32 β€” πŸ‘ 90    πŸ” 26    πŸ’¬ 1    πŸ“Œ 3
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There are a couple of empty chairs at our table β€” want to sit with us?
Reach out to me or any lab member www.oeaw.ac.at/gmi/research... We’ll be hiring two postdocs in 2026.
We’re excited about ambitious and creative ideas and are committed to supporting future group leaders 1/2

29.11.2025 20:46 β€” πŸ‘ 36    πŸ” 24    πŸ’¬ 1    πŸ“Œ 0
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Mathematical Thinking Isn’t What You Think It Is | Quanta Magazine The mathematician David Bessis claims that everyone is capable of, and can benefit greatly from, mathematical thinking.

The mathematician David Bessis believes that mathematical skill is not innate, but learned. β€œGenius is not an essence. It’s a state. It’s a state that you build by doing a certain job.”

27.11.2025 16:46 β€” πŸ‘ 43    πŸ” 18    πŸ’¬ 0    πŸ“Œ 3