How ageing changes our genes — huge epigenetic atlas gives clearest picture yet
A map of DNA methylation changes in human organs could help researchers to discover more targets for anti-ageing therapies.
Featured in Nature News: ARMI's Prof @nireynon.bsky.social & Dr Macsue Jacques have built an “epigenetic atlas” of ageing, mapping DNA methylation changes across 17 human tissues.
📰 Read Nature coverage: www.nature.com/articles/d41...
📃Read Preprint, not yet peer-reviewed: doi.org/10.1038/d415...
18.09.2025 03:08 —
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✨ We are delighted to announce the new AEpiA Committee
We warmly welcome our incoming office bearers:
Chair: Phillippa Taberlay (TAS) @piptaberlay.bsky.social
Co-Chair: Nir Eynon (VIC) @nireynon.bsky.social
Treasurer: Alyson Ashe (NSW)
Secretary: Mark Ziemann (VIC)
03.10.2025 03:16 —
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How ageing changes our genes — huge epigenetic atlas gives clearest picture yet
A map of DNA methylation changes in human organs could help researchers to discover more targets for anti-ageing therapies.
The power of Preprints. Our preprint "DNA Methylation Ageing Atlas Across 17 Human Tissues'
www.researchsquare.com/article/rs-7...
is a subject of a news piece in
@nature.com
How ageing changes our genes — huge epigenetic atlas gives clearest picture yet nature.com/articles/d41...
02.09.2025 23:19 —
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The loop!
31.08.2025 23:36 —
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Meet Dr Bernadette Jones-Freeman from the @nireynon.bsky.social Group at ARMI. She studies how transcription factors drive ageing in muscle and blood, and how gender-affirming hormone therapy affects skeletal muscle health.
26.08.2025 01:31 —
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Crowds stream along a street at night
Over 2.5 million Israelis joined today’s anti-Netanyahu protests, organisers estimate. 300,000 are now in Tel Aviv's Hostage Square. (Haaretz)
17.08.2025 19:19 —
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Please Please don’t put sanctions on Israeli academia.
I’m feeling it and it hurts and distresses me💔.
I and the majority of the academic community oppose the government and its actions. We are fighting every day to change things for the better and we need your help!
Please don’t weaken us🙏
09.08.2025 11:09 —
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Congratulations to Dr. Danielle Hiam, winner of the 2024 AuPS Postdoctoral Publication Prize!
Her impactful work, in BMC Biology, on the importance of considering sex as a biological variable in muscle research.
Think your paper could be next? 2025 applications now open! #AuPS2025 #EMCR #Physiology
07.08.2025 07:44 —
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And a credit for my photo! Goes to my CV as a @nature.com paper 🤣
31.07.2025 08:40 —
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#EpigeneticAging
DNA Methylation Ageing Atlas Across 17 Human Tissues😎
Meta-analysis of 15k human methylomes with age!
Highly intriguing "global disruptor" gene sets (Table S5)
1⃣PCDHGs (A1/2/3/4 B1)
2⃣HOXBs (B3/6 B-AS1/3)
@nireynon.bsky.social bioRxiv 2025
www.biorxiv.org/content/10.1...
28.07.2025 11:03 —
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DNA Methylation Ageing Atlas Across 17 Human Tissues
👉“Our open-access atlas provides a foundational resource for dissecting the molecular architecture of human aging and identifying testable targets for intervention..”
@nireynon.bsky.social and coauthors
www.biorxiv.org/content/10.1...
28.07.2025 21:01 —
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Choosing the Correct Type of Regression Analysis ( my boys) @aliciao.bsky.social @odedrechavi.bsky.social
15.07.2025 10:59 —
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I thought you are running a cartel 😗
15.07.2025 08:25 —
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@odedrechavi.bsky.social tell all your friends and enemies that it is not too late to apply and come work with us @armi @monash in Melbourne, Australia- the capital of the best coffee in the world 🙌
bsky.app/profile/nire...
06.07.2025 08:40 —
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How we’re rebuilding the Weizmann Institute — and our hopes for a better future
Scientific research is at the heart of Israel’s success and has worldwide benefits. Our work will continue despite adversity.
I share Alon’s hope : "I look forward to the day when Israeli scientists can freely collaborate with scientists in Iran and do good for the region and for humanity. I wish the same for scientists in Gaza and throughout the Middle East." @WeizmannScience www.nature.com/articles/d41...
05.07.2025 15:20 —
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Why do I need to write grants and fellowships all the time?
Can we not just pitch it ‘Woodstock of biology’ stile to the committee and get it over with?
@odedrechavi.bsky.social
@itaiyanai.bsky.social
27.06.2025 03:50 —
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👇 science/bioinformatics role in Melbourne
25.06.2025 11:29 —
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Today, we had a lovely dinner in the city of Melbourne. The lab is saying goodbye to Sisi, from China, who finished her Masters studies, and Guilherme from São Paulo, who completed an internship with us.
Good luck and see you soon!
26.06.2025 10:42 —
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👩💻 We’re hiring! Lê Cao Lab at Uni Melbourne @mig-unimelb.bsky.social needs an R dev to power the next-gen of mixOmics 🚀
Love #RStats, #Bioconductor & multi-omics? Help expand mixOmics, run workshops & publish cutting-edge methods.
Apply: unimelb.wd105.myworkdayjobs.com/en-US/UoM_Ex...
23.06.2025 22:20 —
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please share 🙌
Applications for a postdoctoral position in *Bioinformatics* in my lab are still open!
Come and work with us @armilabs.bsky.social @monashuniversity.bsky.social
at the beautiful
Melbourne 🇦🇺
Apply here careers.pageuppeople.com/513/cw/en/jo...
Inquiries: nir.eynon@monash.edu
25.06.2025 10:44 —
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Trump: Iran’s nuclear program has been demolished.
Scientific journal: Please return your editing as soon as possible and pay your 10,000$ publication fees so that you can have access to your paper.
@odedrechavi.bsky.social
@itaiyanai.bsky.social
22.06.2025 05:45 —
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Woodstock.bio2 & Night Science 2025 playlist
Playlist · Vojtěch Svoboda · 102 items · 34 saves
#TCTeAC Woodstock of Biology2
Play list. If you haven’t attended the #conferenceebdallconferences in Prague then look forward for the next one!
open.spotify.com/playlist/1As...
22.06.2025 05:39 —
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You never left?????
22.06.2025 05:34 —
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This is a very difficult time for Israelis and Iranians. If you have friends and colleagues that are affected, reach out to see how they're doing.
19.06.2025 02:10 —
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a missile just hit Saroka hospital where Arab and Jewish doctors and staff work side by side treating everyone.
"our department is standing by our colleagues in Soroka hospital. we carry on doing science for the benefit of hunan kind in Israel and abroad" - Raz Zarivach, Department Chair
19.06.2025 06:07 —
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