Winette van der Graaf

Substandard anticancer medications in clinical care settings and private pharmacies in sub-Saharan Africa: a systematic pharmaceutical investigation Oncology practitioners and health systems in sub-Saharan Africa need to be aware of the possible presence of substandard anticancer products when designing care protocols and evaluating patient outcom...

Substandard anticancer medications in clinical care settings and private pharmacies in sub-Saharan Africa: a systematic pharmaceutical investigation - The Lancet Global Health www.thelancet.com/journals/lan...

This is awful.

📢Excited to announce @benjaminbessemd.bsky.social as EORTC President-Elect, starting in June 2026, following @winettevandergraaf.bsky.social 🙌

Also, we welcome the new chairs of the Scientific Chairs Council: Anne-Marie Dingemans and Jean-Pascal Machiels!🔬🎉

👉 www.eortc.org/blog/2025/06...

🔍Presenting at #ASCO25 as a #poster and now LIVE on our website

Predictors of withdrawal of anticancer drug indications granted accelerated approval: a retrospective cohort study

Read the whole paper here: www.thelancet.com/journals/ecl...
#TheLancet #Oncology #OncologyResearch #MedSky

Prevention of sacituzumab govitecan-related neutropenia and diarrhea in patients with HER2-negative advanced breast cancer

Primary prophylactic G-CSF and loperamide led to a clinically relevant reduced incidence and severity of neutropenia and diarrhea

www.thelancet.com/journals/ecl...
#MedSky

For my #sarcoma colleagues and researchers and @HartwigMedicalFoundation @ecuppen.bsky.social

New paper on implementation of WGS in sarcoma routine medical care in a sarcoma expert center. WGS results of 161 STS were assessed. Actionable targets in 46%, subtype specific added value of WGS. Less in fusion pos STS, more in complex ones.

kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

Same disappointment. The early days of twitter were so informative! Let’s try harder here!

Immensely proud of my colleague and friend Christopher Booth @Queens’s University Kingston who will present the positive results of Challenge #ASCO25 today. Together with Publication in @nejm.org Impressive work. meetings.asco.org/2025-asco-an...

With dosing and duration that are investigated in clinical trials with relevant outcomes for patients reflecting the whole patient population, for regulators and health systems

A new paper from a workshop on pragmatic clinical trials in cancer organised by @eortc.org published in Lancet Oncology.
Fabulous group of co-authors who took part in the workshop. Access to drugs that matter to
patients as ultimate goal.
eur05.safelinks.protection.outlook.com?url=https%3A...

Easter in #Amsterdam

🤝As the clinical trial landscape evolves, so must our strategies for measuring patients’ #QualityofLife to ensure their voice is incorporated in the decision-making process

🔎Takeaways from new article in @thelancetoncol.bsky.social: www.eortc.org/blog/2025/04...
#GivingVoice2Patients @ema.europa.eu

The paper is out!
#Sarcoma genetic predisposition syndromes. Consequences for diagnosis and treatment. Result of an educational session at @ESMO annual meering 2023.

kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

Very interesting presentation by @rubenvanboxtel.bsky.social at Clinical Cancer Genomics conference Amsterdam.
One part of the puzzle of rising incidence of Young Onset CRC addressed with pks mutations.

Great start of Clinical Genomics conference Amsterdam @ecuppen.bsky.social
Very useful oversight of genomic activities in Europe!
@stefanfrohling.bsky.social

This project is on Rare Cancers and we need much more progress in that field!This grant enables further collaborations and will serve other projects.

Try EuropePMC.org

EuropePMC.org is the alternative for PubMed, in case you have problems to access PubMed.

You can freely access all PubMed records at Europepmc.org - I just checked and it's up and running.

Genetic and epigenetic bases of long-term adverse effects of childhood cancer therapy - Nature Reviews Cancer In this Review, Wang and Zhang summarize the major findings of genetic and epigenetic association studies performed on cohorts of survivors of childhood cancer, which provide insights into the long-term adverse effects related to cancer therapy, and present suggestions....

#REVIEW 🚨

In our Feb. issue, Wang & Zhang summarize findings from genetic & epigenetic association studies performed on cohorts of survivors of childhood cancer, providing insights into the long-term adverse effects related to cancer therapy.

📖 👇
https://bit.ly/4eplZ...

It's not "Breaking News" now, since it was announced by NIH yesterday. But it is breaking.......
washingtonpost.com/health/2025/...

Reposting so I can tag with #Medsky

Common Sense Oncology principles for the design, analysis, and reporting of phase 3 randomised clinical trials Common Sense Oncology (CSO) prioritises treatments providing meaningful benefits for people with cancer. Here, we describe CSO principles aimed at imp…

My 2nd World Cancer Day post to highlight work of the Common Sense Oncology team. This new publication identifies key principles for randomized trials of new cancer Rx aimed at improving outcomes that matter most to patients
www.sciencedirect.com/science/arti...

on World Cancer Day it’s important to underscore the HUGE impact academic cancer trials groups e.g @cctg.bsky.social and @eortc.bsky.social have had on improving outcomes. Their studies of new drugs, radiation, surgery & supportive care all have contributed. Pharma is only part of the story.

Ancestral Differences in Anticancer Treatment Efficacy and Their Underlying Genomic and Molecular Alterations Abstract. Systematic multiomic analysis has revealed ancestry-dependent molecular alterations, but their impact on the efficacy of anticancer treatment is yet largely unknown. In this study, we analyz...

Fascinating paper on how different races/ethnicities respond differently to anticancer therapies - such an important thing to understand for personalised medicine #CancerResearch

aacrjournals.org/cancerdiscov...

@pawelsobczuk.bsky.social

I was waiting for you😊

Finally! Welcome! I Have been waiting for you and the other #sarcomapeeps for some time already!