Zheng et al. present their work on Ferroptosis: A Novel Mechanism in Diabetic Keratopathy, iovs.arvojournals.org/article.aspx....

Wei et al. report that Advanced Glycation End-Products Contribute to Delayed Diabetic Corneal Epithelial Wound Healing via the TLR4 Signaling, iovs.arvojournals.org/article.aspx....

Shruti Sharma et al. from Augusta University find that altered carnitine homeostasis modulates hyperosmolarity-induced mitochondrial dysfunction and lipotoxicity in human corneal epithelial cells.
doi.org/10.1167/iovs.67.2.39

Deepak Kumar Bagga from the L V Prasad Eye Institute investigate contrast sensitivity and low-contrast visual acuity in children with low vision.
doi.org/10.1167/iovs.67.2.38

Philipp UhlInstitute et al. from Heidelberg University provide an in-depth analysis of the intravitreal biocompatibility of polyethylene glycol of different molecular weight in an in vivo porcine model.
doi.org/10.1167/iovs.67.2.37

Sujata Das et al from the L. V. Prasad Eye Institute evaluate the histopathological features of Acanthamoeba keratitis and correlate organism morphology, distribution, and density with inflammatory response & clinical parameters in surgically managed cases
doi.org/10.1167/iovs.67.2.36

Yueping Ren et al. from Wenzhou Medical University find that the intracellular C5a–mtC5aR1 axis promotes necroptosis in dry eye through DRP1-mediated mitochondrial dysfunction.
doi.org/10.1167/iovs.67.2.35

Lisa Nivison-Smith et al. from the University of New South Wales find that inner retinal reflectivity loss and concurrent thickening predict short-term conversion to neovascular AMD.
doi.org/10.1167/iovs.67.2.34

Milan Rai, Kaiyip Choi &Henry Ho-lung Chan from The Hong Kong Polytechnic University find that acute ocular hypertension diminishes flicker-induced enhancement in retinal blood flow and full-field electroretinogram in a mouse model.
doi.org/10.1167/iovs.67.2.33

Michaël J. A. Girard from the Singapore National Eye Centre use AI to identify strain-sensitive regions of the optic nerve head linked to functional loss in glaucoma.
doi.org/10.1167/iovs.67.2.29

Elena Sanz et al. from the Universidad Autónoma de Madrid investigate differences in smooth pursuit and associated saccades in children with two common types of strabismus.
doi.org/10.1167/iovs.67.2.28

Hanako Ohashi Ikeda et al. from Kyoto University Graduate School of Medicine find increased gut microbiota diversity in patients with retinitis pigmentosa and implications for disease phenotypes and progression.
doi.org/10.1167/iovs.67.2.27

Vivien J. Coulson-Thomas et al. from the University of Houston characterize the anatomy and morphology of the ocular surface and accessory glands of the Acomys cahirinus mice.
doi.org/10.1167/iovs.67.2.26

Pete A. Williams et al. from St. Erik Eye Hospital find that semaglutide protects retinal ganglion cells against rotenone-induced degeneration via improved glucose metabolism.
doi.org/10.1167/iovs.67.2.25

Brad Fortune et al. from Devers Eye Institute find that microvascular volume loss exceeds nerve fiber layer but not neuroretinal rim tissue loss during progression of nonhuman primate experimental glaucoma.
doi.org/10.1167/iovs.67.2.24

Patricia J. McLaughlin et al. from Penn State University find that mitigation of oxidative stress pathways in the diabetic cornea and lacrimal glands contributes to the rapid reversal of diabetic dry eye by naltrexone.
doi.org/10.1167/iovs.67.2.23

Wenlong Li et al from Shandong Key Laboratory of Eye Diseases find that AIF-1 drives corneal neovascularization by promoting inflammatory macrophage activation via the MAPK and PI3K/AKT/mTOR signaling pathways.
doi.org/10.1167/iovs.67.2.22

Xuehao Cui et al. from the University of Cambridge use integrative proteogenomic analysis to identify genetically supported plasma proteins, metabolites, and pathways in glaucoma.
doi.org/10.1167/iovs.67.2.21

Tatyana Appelbaum, William A. Beltran et al. from the University of Pennsylvania investigate crosstalk between R-Loops, RNA/DNA modifications, and cell death dynamics in canine models of retinitis pigmentosa.
doi.org/10.1167/iovs.67.2.20

Anna Esteve-Garcia et al. from Bellvitge University Hospital investigate genotype-phenotype correlations in ABCA4-associated retinopathy.
doi.org/10.1167/iovs.67.2.19

Lin Xie et al. from The Third Affiliated Hospital of Chongqing Medical University investigate the molecular mechanisms and therapeutic potentials of engrailed-1 in fibrotic scar formation post glaucoma filtration surgery.
doi.org/10.1167/iovs.67.2.18

Ya Xing Wang et al. from Beijing Tsinghua Changgung Hospital investigate ocular and general determinants of intraocular pressure.
doi.org/10.1167/iovs.67.2.17

Qingjun Zhou, Qun Wang et al. from Shandong First Medical University find that taurochenodeoxycholic acid activates calcium signaling to protect against Fuchs’ endothelial corneal dystrophy.
doi.org/10.1167/iovs.67.2.16

Zhijie Li et al. from Henan Eye Hospital investigate how chronic psychological stress alters circadian, immune, and lipid regulatory networks in meibomian glands (MGs) and to assess the efficacy of β-adrenergic blockade in mitigating these effects.
doi.org/10.1167/iovs.67.2.15

Shuai Chang, Xinping Yu et al. from Zhongshan Ophthalmic Center evaluate motor skill impairments in children with intermittent exotropia (IXT), and to investigate associations between clinical visual parameters and motor deficits.
doi.org/10.1167/iovs.67.2.14

Lucia Sobrin, Ayellet V. Segrè et al. from Massachusetts Eye and Ear Infirmary @MassEyeAndEar identify time-dependent glucocorticoid-induced transcriptomic changes in human trabecular meshwork and Schlemm's canal cells.
doi.org/10.1167/iovs.67.2.13

Srinivas R. Sadda et al. from Doheny Eye Institute perform high-resolution OCT profiling of Bruch's membrane in extensive macular atrophy with pseudodrusen-like appearance and geographic atrophy.
doi.org/10.1167/iovs.67.2.12

Benjamin K. Young et al. from Casey Eye Institute Investigate retinopathy of prematurity (ROP) notch physiology, using ultra-widefield optical coherence tomography (UWF-OCT), and a computational model.
doi.org/10.1167/iovs.67.2.10

Soumya Navneet & Bärbel Rohrer from the Medical University of South Carolina find that CR2-fH, a targeted inhibitor of alternative complement pathway reduces dry AMD-like phenotype in AMD patient iPSC-derived RPE cells.
doi.org/10.1167/iovs.67.2.9

Timothy S. Kern et al. from UC Irvine find that theophylline inhibits capillary degeneration in early diabetic retinopathy.
doi.org/10.1167/iovs.67.2.8