BCM Department of Molecular and Human Genetics

Dr. Sharon Plon, Dr. Ronit Marom, Dr. Graham Erwin, Dr. Brendan Lee and Dr. Christine Eng at the @bcmgenetics.bsky.social and Baylor Genetics party #ASHG25 Kick off party.

Tuesday night's @bcmgenetics.bsky.social and Baylor Genetics party was a great way to kick off #ASHG25 conference in Boston, MA. If you are at ASHG, visit the Baylor Genetics at booth 556!

Check out posters from the Baylor Genetics Team at #ASHG25 Halls A & B 2:30 p.m. - 4:30 p.m. ET Wed: Maddie Gillentine PhD & Weimin Bi, PhD; Thurs: Darwin Argueta, MS, CGC, NIkhita Gogate PhD, & Mei Ling Chong, PhD; Friday: Rob Rigobello, MS, CGC, Keri Callegari, PhD, & Haowei Du, Msc, PhD #ASHG2025

Congratulations to Dr. Nicole Wang of the Cheng lab on your successful dissertation! Nicole’s dissertation was “Unveiling the mechanisms of circulating tumor cell clustering.” 🥳 #genetics #genomics #PhD

Neurons in a Huntington's brain Dr. Juan Botas's lab integrates laboratory, animal model and computational approaches to gain a deeper understanding of Huntington's disease and other neurological disorders.

The #ImageoftheMonth is a view through the microscope of #neurons from the brain cortex of a mouse model of #HuntingtonsDisease, courtesy of Dr. Juan Botas Lab. @bcmhouston.bsky.social @bcmgenetics.bsky.social #TCHResearchNews blogs.bcm.edu/2025/10/14/f...

First approved drug for mitochondrial disease could pave way for more treatments Researchers are testing multiple treatments for the rare genetic conditions

First approved drug for #mitochondrialDisease could pave way for more treatments. @bcmhouston.bsky.social researcher Dr. F. Scaglia comments on these emerging new treatments tinyurl.com/jb8bu2pd @bcmgenetics.bsky.social @science.org

Congratulations to Dr. Sharon Plon who was awarded the 2025 Arthur L Beaudet Outstanding Mentorship Award this past Monday! Her talk was titled "Genetic Predisposition to Cancer: From Single Gene Sequencing to Exomes on a Cell Phone". See photos from the event below.

Congratulations to Dr. Kevin Wilhelm of the Lichtarge lab on your successful dissertation! Kevin’s dissertation was “A Meta-Evolutionary Framework for the Discovery and Functional Prioritization of Complex Disease Risk Genes.” 🥳 #genetics #genomics #PhD

Congratulations to Dr. Matthew Cooke of the Herman lab on your successful dissertation! Matthew’s dissertation was “Transcriptional Determinants of Microbial Genome Stability” 🥳 #genetics #genomics #PhD

TMC collaboration: training new kidney, urologic and hematologic researchers Texas Medical Center researchers are working together to strengthen the pipeline for future kidney, urologic and hematologic (KUH) research. Baylor College...

#TXMedCenter collaboration to train new #kidney, #urologic and #hematologic researchers. #HAIKUH @bcmhouston.bsky.social #Goodell_Lab @bcmgenetics.bsky.social www.bcm.edu/news/tmc-col...

Dr. Graham Erwin @grahamerwin.bsky.social receives NIH New Innovator Award! www.bcm.edu/news/dr-grah... @bcmhouston.bsky.social @bcmgenetics.bsky.social #BCMCancerCenter

NIH awards Baylor more than $15 million to fund two rare diseases consortia The funding is to renew the Brittle Bone Disorders Consortium for five years and to launch the Rare Organic Acidemias Research Consortium.

NIH awards Baylor more than $15 million to fund two #rareDiseases consortia. @bcmhouston.bsky.social @bcmgenetics.bsky.social @rarediseasesint.bsky.social blogs.bcm.edu/2025/09/30/f...

Medical Genetics Multiomics Laboratory The Medical Genetics Multiomics Laboratory (MGML) is an academic clinical genetic testing laboratory from Baylor College of Medicine. The MGML supports...

Big news! The Medical Genetics Multiomics Lab (www.bcm.edu/departments/...) @bcmhouston.bsky.social has earned CAP accreditation, recognizing its excellence in lab quality and patient care. Congrats to Dr. Pengfei Liu and the team! 👏 #Genetics #LabExcellence

Congratulations to Dr. Matthew Alvos of the Botas lab on your successful dissertation! Matthew’s dissertation was “Targeting SERPINs as a therapeutic strategy to ameliorate neurodegenerative disease.” 🥳 #genetics #genomics #PhD

AI connects mutations, protein modifications and disease The new AI tool, called DeepMVP, significantly outperforms previously published models and has implications for the development of novel therapeutics.

#DeepMVP improves the ability to predict gene #mutations that may lead to #disease. B. Zhang, C. Wang et al #naturemethods @bcmgenetics.bsky.social @bcmhouston.bsky.social #BCMCancerCenter blogs.bcm.edu/2025/09/09/f...

The GReAT Job Award recipients for January - June 2025 are Darwin Argueta, Ashley Hirt, and Lauren Westerfield.

Genetic Resource Association of Texas (GReAT) Job Awards acknowledge @bcmhouston.bsky.social employees who go above and beyond regular job responsibilities in service of @bcmgenetics.bsky.social mission to transform medicine with the science and practice of genetics and genomics.

Congratulations to Dr. Shenglan Li who was named the recipient of the 2025 The Shan and Lee-Jun Wong Fellowship Award! This award provides support to senior postdocs & junior faculty who focus on mitochondrial and/or cancer biology, especially translational science & diagnostics.

Congratulations to the 2025 Rolanette and Berdon Lawrence Family Achievement in Genetics award recipients: Dr. Lindsay Burrage, English Laserna, Jefferson Sinson, and Sherri Weaver!

The Rolanette and Berdon Lawrence Family Achievement in Genetics Awards recognize scientific, clinical, educational, and service achievements of @bcmgenetics.bsky.social
faculty, students/trainees, and administrative staff.

Congratulations to Dr. Pengfei Liu on receiving the 2025 Baylor College of Medicine Young Alumnus Award! Read more about this award and other alumni awards given by Baylor College of Medicine this past weekend. www.bcm.edu/news/baylor-...

AI reveals how protein modifications link mutations to disease Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations...

Researchers at @bcmhouston.bsky.social have developed an #AI model that reveals how protein modifications link genetic #mutations to #disease. B Zhang, C Wang, B Wen, K Li et al. @natmethods.nature.com @bcmgenetics.bsky.social #BCMCancerCenter www.bcm.edu/news/ai-reve...

New #AI model reveals how #proteinModifications link genetic #mutations to #disease. B Zhang, C Wang, B Wen, K Li et al. @natmethods.nature.com @bcmgenetics.bsky.social @bcmhouston.bsky.social #MedicalIndustryToday www.medicalindustrytoday.com/article/8433...

What makes some identical twins look and behave differently? Metastable epialleles may sound like complex science, but they help explain why identical animals can still look and act differently. For years, scientists asked why two mice with identical DNA could ...

Dr. Robert A. Waterland and his team find new insight into why some identical twins look and behave differently. #genes #twins

Statistical tool reveals genetic drivers of complex human diseases paving the way for personalized genetic medicine The Causal Pivot accounts for genetic diversity within a disease and can be adapted to the clinic of tomorrow.

Computational tool helps determine if a condition such as #Parkinsons arises from several mutations or one rare variant. C. Shaw, J. Belmont, J. Shulman et al @riceuniversity.bsky.social @bcmhouston.bsky.social #TCHResearchNews @ajhgnews.bsky.social @bcmhgsc.bsky.social blogs.bcm.edu/2025/08/21/f...

Computational approach meets biology to connect neural progenitor cells with human disorders For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis...

The cells giving rise to new #neurons in the adult #brain have been elusive. M Maletic-Savatic, G. Cappuccio, W. Choi, F. Semerci, Z. Liu et al found a way to ID them. @bcmhouston.bsky.social #DuncanNRI @stemcellreports.bsky.social #TexasChildrensHospital www.bcm.edu/news/computa...

Congratulations to Dr. Sau Wai Cheung on receiving the 2025 ACGA Lifetime Achievement Award! This award recognizes individuals who have made outstanding contributions to the field of genetics and demonstrated exceptional leadership in advancing scientific research and education.

Drs. R Chen, HMJ Hussain et al have identified C19orf44 as a novel inherited #retinalDisease-associated #gene jmg.bmj.com/content/jmed... @bcmhouston.bsky.social @bcmgenetics.bsky.social #JMG_BMJ

Congratulations to Dr. Brandon Garcia of the Posey lab on your successful dissertation! Brandon’s dissertation was “Retrieval-Augmented Phenotype Extraction with Large Language Models” 🥳 #genetics #genomics #PhD

🚨 New perspective piece in @ajhgnews.bsky.social! 🚨
We developed a hands-on training resource for large-scale genomic data analysis in the All of Us Researcher Workbench, now published here: