Meningeal mast cells, via the receptor Mrgprb2/X2, orchestrate brain inflammation after stroke by recruiting and promoting the transfer of skull bone marrow neutrophils into the brain @cellcellpress.bsky.social
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25.07.2025 02:11 — 👍 3    🔁 3    💬 1    📌 0

A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis Meningeal mast cells, via the receptor Mrgprb2/X2, orchestrate brain inflammation after stroke by recruiting and promoting the transfer of skull bone marrow neutrophils into the brain, highlighting these mast cells as key regulators of brain immunity and of the skull bone marrow-meningeal-brain network.

Now online! A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis

24.07.2025 14:59 — 👍 5    🔁 3    💬 0    📌 0

A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis Meningeal mast cells, via the receptor Mrgprb2/X2, orchestrate brain inflammation after stroke by recruiting and promoting the transfer of skull bone marrow neutrophils into the brain, highlighting th...

Very excited to share our new work out today @cellpress.bsky.social. Here, we propose that meningeal mast cells regulate brain inflammation after stroke by coordinating immune infiltration from the skull bone marrow, through the meninges, and into the brain!

www.cell.com/cell/fulltex...

24.07.2025 17:21 — 👍 28    🔁 9    💬 1    📌 1

A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis The immune environment surrounding the brain plays a fundamental role in monitoring signs of injury. Insults, including ischemic stroke, can disrupt t…

MrgprB2 back in the news. Stroke! Big new @cellpress.bsky.social paper with a lot of good friends on it: www.sciencedirect.com/science/arti... congrats to Ruchita, Risheng, Dr. Dong and the great @nathachitlim.bsky.social

24.07.2025 15:24 — 👍 5    🔁 1    💬 1    📌 0