Geng-Jen Jang

Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior Nature Communications - Chromatin heterogeneity in the cell nucleus modulates the size, mobility, and formation of biomolecular condensates; decreasing chromatin heterogeneity correlates with...

Congrats to Jing @jesszhiyuezhao.bsky.social‬
& @dnamystrom.bsky.social‬ on cool manuscript!!! Reveals how cell nucleus is a heterogeneous material, w chromatin organization controlling formation & phase behavior of nuclear condensates. #CellBiology #Chromatin #PhaseSeparation rdcu.be/evWxR

Cold-induced nucleosome dynamics linked to silencing of Arabidopsis FLC Temperature influences nucleosome dynamics, and thus chromatin, to regulate gene expression. Such mechanisms underlie the epigenetic silencing of Arabidopsis FLOWERING LOCUS C (FLC) by prolonged cold....

We are happy to share our work on local #nucleosome dynamics integrating #temperature inputs into an #epigenetic switching mechanism.

⚠️ Preprint alert!!
www.biorxiv.org/content/10.1...

This achievement is the result of a collaborative effort between the Plant Biology and Physics of Life groups. Interdisciplinary research can be challenging, but it's rewarding. Stay tuned for more of our upcoming papers! @johninnescentre.bsky.social @sulteavn.bsky.social

Our paper has been published! We used in vivo single-particle tracking to demonstrate that the assembly of core FCA oligomers into functional macromolecular condensates.
Thanks to all the authors and colleagues!