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Nollen Lab

@nollenlab.bsky.social

Using C. elegans to study Molecular Neurobiology of Aging. Lab at the European Research Institute for the Biology of Ageing in Groningen, the Netherlands (ERIBA, UMCG)

128 Followers  |  82 Following  |  7 Posts  |  Joined: 09.01.2025
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Posts by Nollen Lab (@nollenlab.bsky.social)

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Condensate-Driven Triglyceride Depletion Links α-Synuclein to Mitochondrial Dysfunction Inclusions of α-Synuclein (αSyn) characterize multiple age-related neurodegenerative diseases, including Parkinson’s disease (PD) and Multiple System Atrophy (MSA). While interactions between αSyn and...

🚨 New preprint alert! We uncovered a link between Parkinson’s protein α-synuclein and fat metabolism. α-syn inclusions disrupt lipid droplets and deplete TAGs during aging & MCFAs restore movement in α-synuclein worms.
👉 Targeting fat metabolism could help to combat Parkinson’s! shorturl.at/2mVG6

21.11.2025 08:15 — 👍 3    🔁 2    💬 0    📌 0
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Last week was a very proud moment for the Nollen lab: Lale Güngördü successfully defended her PhD thesis, “Modifying TDP-43 Toxicity”! 🎓🔥
Congratulations, Dr. Güngördü! We are so proud of you!
We had a fantastic day celebrating this milestone and we can’t wait to see what she will achieve next! ✨🔬

06.11.2025 15:01 — 👍 0    🔁 0    💬 0    📌 0
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Excited to announce that Suzanne Couzijn and Anna Ainslie have received a grant from Stichting ParkinsonFonds🎉👏 for their project “Protecting against alpha-synuclein toxicity at molecular and physiological levels”. They will investigate the mechanisms driving alpha-synuclein toxicity in C. elegans🪱🧠

28.08.2025 09:04 — 👍 6    🔁 0    💬 0    📌 0

Congratulations Jamil!

11.02.2025 13:53 — 👍 0    🔁 0    💬 0    📌 0
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🌍 Today in the Nollen Lab, we are celebrating the International Day of Women and Girls in Science! 🔬🧪 Here's to a future where every girl feels empowered to lead in science. ⚛️

#WomenInScience #STEMinspiration #IDWGS
@ellennollen.bsky.social

11.02.2025 13:52 — 👍 3    🔁 0    💬 0    📌 0

We’d love to connect with researchers, advocates, and anyone curious about the biology of ageing and neurodegenerative diseases! 💬

09.01.2025 12:06 — 👍 0    🔁 0    💬 0    📌 0

We’re the Nollen Lab, and we’re excited to join the scientific community on Blue Sky!🌞 Our lab uses the nematode worm C. elegans to understand the molecular neurobiology of ageing and neurodegerative diseases 🧠🔬🧪🪱
#Neurobiology #AgingScience #Parkinsons #ALS #Alzheimer #Metabolism #Ageing #Celegans

09.01.2025 12:06 — 👍 10    🔁 0    💬 1    📌 0