Hore Lab

1/ I’m very excited to share my postdoc work with @kseskv.bsky.social, in collaboration with @oligriffith.bsky.social. We explore embryonic DNA methylation reprogramming in the fat-tailed dunnart, an Australian marsupial 🦘🌏 www.biorxiv.org/content/10.1...

‘It was a bombshell’: Govt culls pest eradication company Is the financially stretched Department of Conservation best to lead the country’s cooperative mission to eradicate pests by 2050?

Gutting to see Predator Free 2025 disestablished in the latest budget and rolled into DOC, which in turn is facing its own budget challenges. Lost funding and, more importantly, capacity and capability through this disestablishment makes the goal harder to achieve.

newsroom.co.nz/2025/05/26/i...

Divergent DNA methylation dynamics in marsupial and eutherian embryos Nature - A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.

Delighted to see this high-quality marsupial reprogramming work from @lab-turner.bsky.social and kiwi @bryonyleeke.bsky.social (rdcu.be/emAjn). We also saw muted PGC reprogramming in brushtail possum rdcu.be/emAk5. Same is true for Zebrafish. Maybe eutherians and complete erasure is the outlier?

Divergent DNA methylation dynamics in marsupial and eutherian embryos - Nature A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.

We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵

Fascinating to learn more about the brushtail possum in its home range - and wonderful to see the NZ possum assembly (rdcu.be/ekB2O) helping clarify taxonomy.....Congrats Shelby Middleton, @pezoporus.bsky.social and co-authors
academic.oup.com/zoolinnean/a...

Australia’s common brushtail possum has long been neglected in terms of its taxonomy. My amazing PhD student Shelby Middleton along with a stellar supervisor team has attempted to resolve this species. Check it here: academic.oup.com/zoolinnean/a...

Really proud of @sebasalco.bsky.social's mahi on this one, and grateful to the iwi and hapū who entrusted us with their ngā ika moana taonga. @royalsocietynz.bsky.social, University of Otago, Genomics Aotearoa and ORG.one provided funding, and thanks to all incl coauthors who provided tautoko!

Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1921

Excited to see issue on ribosome heterogeneity and specialisation out @royalsociety.org Philosophical Transactions B. Thanks to authors & co-editors @liamfaller.bsky.social @andershlund.bsky.social Maria Barna. Wonderful cover Bulat Fatkhullin! #ribosomes royalsocietypublishing.org/toc/rstb/202...

YouTube video by Epigenetics Otago Predicting ‘male-time’ with the Androgen Clock

Delighted to share our 'Androgen clock' paper in #PNAS ow.ly/Guts50ULghF - the first way to predict long-term androgen exposure using DNA alone. We so much more than the sequence we are born with! Stellar work (and animation - SOUND ON) by Dr Victoria Sugrue youtu.be/GL55yjMalII