Adam MacLean

Post a pic, no context, to bring some zen to the feed.

Shout this from the rooftops!

ALSO: PIs who must decline reviews, please nominate the qualified students and postdocs from your lab!

A screenshot of the following text: "A teacher of undergraduate courses belongs in a class with P.R. men, with entertainers, with propagandists, with preachers, with magicians, with gurus. Such a teacher will be successful if at the end of the course every one of his or her students feels they have taken “a good course,” even though they may not quite be able to pin down anything specific they have learned in the course."

As I hurtle headlong towards the coming semester, I am really feeling these epic closing words of advice from Gian-Carlo Rota.

[very grateful to the transcription from Leo Goldmakher, h/t @lianafaye.bsky.social]

web.williams.edu/Mathematics/...

This is fascinating! I thought I saw some flowering driving down the 395 over the weekend (near the 14 junction) but I did not take any pictures.

Yes except in my head it has to be Ofc. ofc just looks odd 🤷‍♂️

Intracellular competition shapes plasmid population dynamics From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...

Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/
www.science.org/doi/10.1126/...

"I was delighted to publish an article in Development fee-free thanks to the Read & Publish agreement between the University of Southern California and The Company of Biologists. Not only is it a huge benefit for researchers to be able to publish Open Access while navigating uncertain funding environments, but I am thrilled that my institution and others through such agreements support The Company of Biologists: a not-for-profit publisher with a track record of supporting scientists and the work they do." Adam L. MacLean, University of Southern California, USA

Thank you Adam Maclean @adamlmaclean.bsky.social for sharing your experience of fee-free Open Access publishing in @dev-journal.bsky.social via our Read & Publish agreement with The University of Queensland.

See all institutions: www.biologists.com/library-hub/...

#OA #OpenAccess #ReadAndPublish

The ability of kids to convince me they know more than they know is truly amazing.

Exhibit: family charades. I am acting, 7yo is guessing.
One word; two syllables.
Meaning: something you eat with that is not a spoon.
First syllable: chop.
Second syllable: rhymes with lick.
7yo: Knife!

Ah I see okay!

we aren't allowed to write cocaine?

🤌🐀

Cool paper. Was the ad hominem really necessary though?

www.science.org/doi/10.1126/...

S3 Ep1: SMB 2025 Podcast Episode · Biology in Numbers · 09/29/2025 · 53m

Really enjoyed talking about mathematical biology (and a little about being an associate dean) in @parmvir.com's Biology in Numbers podcast on the 2025 @smbmathbiology.bsky.social annual meeting!

Bolero superfans, don't @ me! 🧪

(I'm at 33:43)

podcasts.apple.com/us/podcast/b...

Please start following @natbiomedeng.nature.com! It's an alive account now and we will start posting good content!

Who knows if the cows were more or less interested in my poster than the poster session attendees would have been.

Also good idea @mathcancer.bsky.social to flip the script, it was great to hear from our host Parmvir too!

This was fun and great to learn about the research (and trivia) of colleagues from #SMB2025 this summer in Edmonton. Thanks to @parmvir.com for hosting a great podcast 🙌 🧬 🔢

podcasts.apple.com/us/podcast/s...

Also starring:
@adamlmaclean.bsky.social
@gosiaweh.bsky.social
@mathcancer.bsky.social
@thomasewoolley.bsky.social
Luis Sordo Vieira
Mobolaji Williams
Kira Pugh
and Francisca Olajide

@smbmathbiology.bsky.social #scicomm #BiologyInNumbers

Phylogenetic tree inference from single-cell RNA sequencing data www.biorxiv.org/content/10.1... #singlecell

Super excited to see our reference bias work out in Cell! Reviewers gave us some excellent ideas, and Maria added on some new analyses that broke down how SNPs from heterospecific references mapped or did not map in a conspecific reference.

😂 perfect

Wound-dependent leg amputations to combat infections in an ant society Frank et al. provide the first example of the use of amputations to treat infected leg wounds in a non-human animal. The findings demonstrate that ants can adapt their treatment modality depending on ...

Sometimes I get the feeling I'm working in the wrong subfield of biology

www.cell.com/current-biol...

Online now! Tumor dynamics & spatial proteomics-informed personalized predictions of growth & response

Beyond RECIST: mathematical modeling and Bayesian inference reveal the importance of immune parameters in metastatic breast cancer

www.biorxiv.org/content/10.1...

"When they see us coming
The birdies all try an' hide
But they still go for peanuts
When coated with cyanide."

Discovering mechanisms of response via CSI (Cancer Systems Immunology) mathematical-oncology.org

In this week's post Jesse Kreger (@adamlmaclean.bsky.social‬) discusses his latest work in #cancer #systems #immunology together with Edgar Gonzalez to study the mechanisms of response of breast cancer to #checkPointInhibitors

Thanks for the great science and great company. Next year will be time to swap the poutine for pilsner and I'll hope to see you in Graz! #SMB2025

For the most part everything ran on time! Also crucial to success of course, as well as being just good manners. I wholeheartedly endorse the session chair energy of Kelsey Gasior:

"If you run over time, I will body slam you off stage."

I was overall really impressed with the organization, bravo to the team. The venue worked well; this is IMO crucial to a great conference experience in that it permits ease of hopping between parallel sessions (bar a few squeaky doors) to cram in as many minisymposia talks as is humanly possible.

In terms of themes, I feel like more than even I saw an emphasis on rigorous inference of one's models to data, not just in methods talks but in applications; big fan of that! I also appreciated great talks that dug deep into complex tumor microenvironments and cell state transitions within them.

Couldn't leave Canada without breakfast poutine. Some scattered thoughts and Takeaways from #SMB2025...

I had a super fun week, so many conversations, short and long, with science friends old and new.

Yep. There are a lot that don't say a lot.