George Heath

Christoph Gerber — a life devoted to the nanosciences

Happy Birthday #AFM!
To celebrate the first description of the atomic force microscope (AFM) in Physical Review Letters, we spoke to our longstanding honorary member Christoph Gerber, who, together with Carl Quate and Gerd Binnig, invented this groundbreaking instrument.
@unibas.ch bit.ly/4raqCOm

AFM & SPM 2026 - invited speaker poster

📢 AFM & SPM Meeting 2026 | 📍Leeds, UK | 📅 23–25 June

Excited to share the confirmed speaker list so far for the RMS AFM & SPM Meeting 2026, taking place in Leeds this summer.

More info and registration:
www.rms.org.uk/rms-event-ca...

@royalmicrosoc.bsky.social
#AFM #SPM

Archaeal cells whose DNA has been stained with a blue dye. Zoomed-in images of mutant cells that display chromosome segregation defects.

High-resolution images of DNA-protein complexes obtained with atomic force microscopy. Upon binding, the protein bridges distant sites, forming loops.

📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social

www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!

Speakers, registration, and more details coming soon. Please get in touch if you would like to contribute to the training, exhibition, sponsorship or just feeding in ideas.

Meeting features:
🔹 Training and development day (optional)
🔹 Instrument Exhibitions to showcase cutting-edge tools and technologies
🔹 Poster sessions, contributed and invited talks
🔹 Discussions about future initiatives for the field
🔹 Networking and social events

SPM areas of interest:
🔸 Material Science
🔸 Biosciences
🔸 SPM in UHV
🔸 New SPM methods and techniques
🔸 New Computational methods for SPM

This meeting will bring together speakers and participants from around the world, with a focus on cross-method SPM collaboration, knowledge exchange and developing the next generation of SPM researchers.

Image featuring University of Leeds campus and text overlay: AFM & SPM 2026, June 22-25, Leeds, UK

Join us in Leeds next Summer for: AFM & SPM 2026

Co-organised with Lekshmi Kailas, Kristina Rusimova, Samuel Jarvis and Jess Cole from the Royal Microscopical Society.
#AFM #SPM #Microscopy

Exciting work led by @nano-chalmers.bsky.social delivered in collaboration with @georgerheath.bsky.social introducing a rationally designed DNA origami system for the multiplexed detection of miRNA in crude RNA extracts via nanopore sensing.

We're also building a list of links to public #AFM image datasets to help the community find, share, and re-analyse datasets more easily.

Know of any open AFM image data? Feel free to add a link it here:
george-r-heath.github.io/NanoLocz/doc...

NanoLocz 1.3 Workshop Join for a short, practical session to get the most out of NanoLocz – AFM data analysis tool.

Join a user meeting (all welcome):
eventbrite.co.uk/e/nanolocz-1...

• Wed 11 June · 09:30-10:30 BST
(10:30 CEST 🇪🇺, 14:00 IST 🇮🇳, 16:30 CST 🇨🇳, 17:30 JST 🇯🇵)

• Tues 17 June · 16:00-17:00 BST
(17:00 CEST 🇪🇺, 11:00 EDT 🇺🇸, 08:00 PDT 🇺🇸, 12:00 BRT 🇧🇷)

Squeeze more out of your AFM images with NanoLocz v1.3 💪
Download the updated version here:
github.com/George-R-Hea...

Excited to report our latest research on new “molecular glues” that specifically lock the BRCC36 isopeptidase complex (BRISC) in an autoinhibited state and reduce interferon signalling. This first-of-its-kind approach could reshape how we target large deubiquitylase (DUB) complexes.

rdcu.be/edRwF

A structural biology compatible file format for atomic force microscopy - Nature Communications Here, the authors developed a pipeline to transform AFM data into 3D-density files for cross-methodology structural biology analysis. Combined with molecular dynamics flexible fitting, the approach yi...

What a contribution this article is to the bioAFM community. 👍👍👍
www.nature.com/articles/s41...
#AFM

A packed conference audience listens intently to a speaker who is out of shot.

The abstract submissions deadline for #mmc2025 has been extended!

Submit your abstract by *Friday 28 February* and join our impressive line-up of speakers!

rms.org.uk/resource/mmc...

@rmsearlycareer.bsky.social @bioimaginguk.bsky.social @yorkbioimaging.bsky.social @micro-au.bsky.social

A presenter gives a talk from behind a podium at mmc2023.

📢Abstract submissions deadline for #mmc2025 is *tomorrow* (14 February).

Don't miss the chance to present your work at Europe's largest #microscopy and #imaging event taking place this year!

Abstract submissions: mmc-series.org.uk/conference/a...

@rmsearlycareer.bsky.social

Life pushed to extremes: probing the mechanisms of chromosome segregation in thermophilic Archaea at University of York on FindAPhD.com PhD Project - Life pushed to extremes: probing the mechanisms of chromosome segregation in thermophilic Archaea at University of York, listed on FindAPhD.com

📢 New round of PhD studentships.
Open to applicants worldwide.

📅 Deadline 14th March
www.findaphd.com/phds/project...

#microsky #archaeasky #chromosome 🧬🧬🧬
@steve-quinn-lab.bsky.social @georgerheath.bsky.social

Join us in beautiful York, UK!

Mechanisms of RCD-1 pore formation and membrane bending - Nature Communications The mechanism of RCD-1 regulated cell death in fungal cells is unknown. Here, the authors use AFM to uncover two mechanisms by which RCD-1 proteins form pores in lipid membranes, and discover a membra...

Check out the latest work on RCD-1 from our lab:
www.nature.com/articles/s41...
Congrats to my labmates! 👏
#AFM #RCD-1

Postdoc Varun Gupta will be presenting some great AFM in the 1st session of the Linz Winter Workshop this weekend ⛷️👏

👋👋 Hi everyone! The Astbury Centre is now on Bluesky. Follow along for updates about exciting Astbury Centre science. For now, we have put together a starter pack of members of the Astbury Centre community.

15th January is the abstract deadline for the upcoming #AFMBioMed2025 in #Barcelona! New formats, events… I wouldn’t miss it—save the date #April2025!

Proud to be part of this paper published in @naturecomms.bsky.social. Using high-speed AFM, we have visualized the real-time translocation of substrate polypeptide by the single molecule of SecYEG-SecA!!!
Please check this amazing video taken by high-speed AFM!!!
www.nature.com/articles/s41...

Please share, we have #PhD opportunities for anyone interested in filming the #Biophysics of life at the nanoscale.

Full details at: heath-afm-lab.github.io/positions/

Projects based around developing and applying High-Speed Atomic Force Microscopy methods to understand molecular dynamics.

Diagram showing archaeal cells containing two chromosomes bound by proteins prior to cell division.

📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea.

Supervised by me, @Steve Quinn & @georgerheath.bsky.social

www.findaphd.com/phds/project...
Open to Applicants Worldwide!

📅 January 6, 2025

#microsky #archaeasky

AFM starter pack. Sorry if I missed anyone, relatively small numbers at the moment. Please share, nominate others/yourself (any career stage). I will also try to add incoming new users regularly.
go.bsky.app/MSz2t33

First attempt in a (loosely defined) Single-Molecule Biophysics starter pack. Please share and (self-) nominate. go.bsky.app/CteFZM5

Thank you

This is the NanoRacer 🏁

Hi Johannes, great list! could I be added please?