Emily A. Aery Jones

Stand up for Science Stand up for Science

MARK YOUR CALENDARS!

THIS SATURDAY, MARCH 7TH we need YOU to rally with us in WASHINGTON D.C.

We have three goals:
SAVE SCIENCE.
PROTECT HEALTH.
DEFEND DEMOCRACY.

Visit this link zurl.co/5cOsu to learn more!

#standupforscience
#science
#March7DC
#savescience
#rally

WASHINGTON DC RALLY LOCATION In front of the Hirshhorn Museum, Mall Walk

SCIENCE FIGHTERS!!!

We are rallying on
SATURDAY, MARCH 7th in
WASHINGTON D.C. to
TAKE BACK OUR SCIENCE

Visit this link to learn more! :
fight2win.standupforscience.net/DC-March/

Rally from 1 - 3PM!

SAVE SCIENCE.
PROTECT HEALTH.
DEFEND DEMOCRACY.

#March7DC
#science
#standupforscience

Dendrites help neuroscientists see the forest for the trees Dendritic arbors provide just the right scale to study how individual neurons reciprocally interact with their broader circuitry—and are our best bet to bridge cellular and systems neuroscience.

Dendritic arbors provide neuroscience with an ideal opportunity to study how individual neurons interact with their broader circuitry and are the field’s best bet to bridge cellular and systems neuroscience, writes @justinkohare.bsky.social.

#neuroskyence

www.thetransmitter.org/dendrites/de...

Screening, sorting, and the feedback cycles that imperil peer review The process of peer review is vital to contemporary science, but is also under enormous strain. This study uses mathematical models to dissect the threats to the long-term viability of peer review, su...

1. Kevin Gross and I have a new paper out today PLOS Biology.

We used economic models based around screening games and the market for unpaid labor to highlight a meltdown cycle threatening peer review.

Hippocampal trace coding dominates and disrupts place coding https://www.biorxiv.org/content/10.64898/2026.02.17.706430v1

The BRAIN miniseries | Investigating the link between vascular health and neurodegeneration in underrepresented populations In this podcast, neuroepidemiologist Cellas Hayes shares his research into the links between vascular health and neurodegeneration, specifically in underrepresented populations.

In this interview with @c3llas.bsky.social, a neuroepidemiologist and postdoctoral researcher at @stanfordmedicine.bsky.social, we explored the link between vascular health and neurodegeneration, particularly in underrepresented populations >>> www.biotechniques.com/podcasts/bhm... 🧪

Neuronal spiking in the mammalian forebrain is dominated by a heterogeneous ground state Neuronal firing patterns have significant spatiotemporal variability with no agreed-upon theoretical framework. Using a combined experimental and mode…

With this one in print, I think I finally earned that PhD... 😅
Presented for the first time at the cosyne when the world ended (March 2020). I'll bring over a summary thread from twitter when it was still twitter...

www.sciencedirect.com/science/arti...

New paper alert! 🚨

We found that the brain's compass is remarkably stable at two scales

1️⃣ the system maintains its internal organization for weeks
2️⃣ It "remembers" its orientation for weeks, even after a single visit

This may be key to how the brain aligns its other maps.

Paper: rdcu.be/e3waP

"Even if the nervous system were composed of perfectly reliable components, existing theory predicts a never-ending flow in the configuration space of any adaptive neural circuit..."

Prefrontal neural geometry of learned cues guides motivated behaviours - Nature The dorsomedial prefrontal cortex encodes the value, salience and valence of learned stimuli along distinct neural dimensions, and the geometry of these representations shapes motivated behaviours in ...

Can you easily distinguish between value, valence, and salience?

Probably not, but the prefrontal cortex of mice seems to achieve this by creating a sort of multidimensional orthogonal neural space, where each dimension corresponds to one of these subjective elements

www.nature.com/articles/s41...

Freeman Hrabowski III, the President Emeritus from the University of Maryland Baltimore County, giving a TED talk.

This is a powerful message from Freeman Hrabowski.

🧵

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Applications for PUMAS are now open! PUMAS is designed to support and mentor community college students, providing them with hands-on research experience and a pathway into the sciences.

Past interns share their experiences, and how the program impacted their lives.

https://bit.ly/4izhKyd

GitHub - SAFE-Labs-Docs/Lab-Handbook Contribute to SAFE-Labs-Docs/Lab-Handbook development by creating an account on GitHub.

If you're writing a lab manual, check out SAFE Labs guidelines (github.com/SAFE-Labs-Do...) by @pipcoen.bsky.social and co. An excellent resource to help establish transparency and a positive lab environment. Now featuring the first non-European lab examples (from yours truly).

The hippocampal map has its own attentional control signal!
Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See 📹 in post 4/6 and preprint here 👉
www.biorxiv.org/content/10.6...
🧵(1/6)

"...open science behaviors function as honest signals of a researcher’s willingness to expose their work to scrutiny. As with honest signalling in biological systems, the value lies ... in that these behaviors are sufficiently costly ... that they are disproportionately avoided by [bad] actors"

Excited to share our new preprint for this project!

Reward as drive reduction, the return!

This opinion piece on the explanatory and unifying power of the homeostatic reinforcement learning framework is amazingly accessible, despite its technical nature, and extremely insightful 👏

www.sciencedirect.com/science/arti...

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A roadmap for conducting more inclusive research on brain resilience in ageing and dementia - Nature Reviews Neuroscience Guidance is lacking on how to best integrate sex, gender and social and structural determinants of health into neuroscience research on brain resilience in ageing and dementia. In this Roadmap article...

A roadmap for conducting more inclusive research on brain resilience in ageing and dementia — a Roadmap article by M. Natasha Rajah, Roger A. Dixon, Gillian Einstein, Yaakov Stern & The Brain Resilience and Diversity in Aging and Dementia Collaboratory

www.nature.com/articles/s41...

We will import and format your protocol Paper protocols floating on your benchtops? We can digitize them for you!

Happy International Love Methods week!

The Crick partners with @protocolsio.bsky.social to share open methods, and if you happen to be a Crick researcher, you can use their protocol writing up service for free (while codes last!)

www.protocols.io/we-enter-pro...

Non-invasive tracking of hippocampal theta oscillations Hippocampal theta oscillations play a crucial role in the formation of episodic memories by binding multisensory information into coherent episodes. Brain stimulation studies suggest that memory performance can be modulated by targeting these oscillations, offering a potential way of treating memory disorders. However, to effectively engage these rhythms, precise knowledge about their presence, frequency, phase and location is required, which has been a challenge, particularly for non-invasive methods such as magnetoencephalography (MEG). Here, we first asked if hippocampal signals are detectable in MEG recordings. Using simultaneous MEG-intracranial EEG (iEEG) data, we show that invasively recorded hippocampal activity is reflected in MEG sensor signals, demonstrating the feasibility of detecting deep-brain activity non-invasively. Building on this, we introduce a MEG-based analysis pipeline to track hippocampal theta frequency over time. Applied across three independent datasets, the pipeline captured characteristic hippocampal theta frequency patterns in both rodents and humans, and MEG-derived hippocampal frequencies were consistent with those observed simultaneously in intracranial EEG. These findings provide evidence that MEG can reliably track individual hippocampal oscillatory dynamics, paving the way for future non-invasive closed-loop interventions that adapt stimulation frequency and timing to ongoing oscillations. ### Competing Interest Statement S.H. acts as scientific adviser to Clarity Technologies Inc. and L.P. is part-time employed by MEGIN Oy, which did not influence the study's design or interpretation. Medical Research Council, MR/W006804/1 UKRI Frontier Research, EP/X023060/1

MEG continues to amaze me. Now it can approximate hippocampal theta oscillations non-invasively! www.biorxiv.org/content/10.6...

THIS! This is the type of conversation I'm eager for our community to have. How many big challenges stand in the way of impactful solutions? What's our plan to tackle them? It's up to us to figure these things out (ultimately we're the ones steering the ship).

Thank you @simonwheeler.bsky.social!

A beautiful Monday morning read about the trials and triumphs of peering into the darkness towards discovery. Well worth your two minutes to drink in the whole thread.

Join Join the Community for Rigor to get regular updates about our work, early access to materials, and participate in events that bring together researchers passionate about making better science every…

The Community for Rigor is a not-for-profit initiative to create a FREE, online curriculum to teach, learn, and practice scientific rigor.

Join us at c4r.io/join and let us help you acquire the knowledge and skills you need to do better, more rigorous science.

#ExperimentalDesign #Rigor #PhDLife

Our lab's first Friday coffee hour! Starring our yard sale-acquired espresso machine, whom we've dubbed Maria.

Kicking off the new year with our first ever Aery Jones lab meeting!

#GRWM for my first day as a professor! @comm4rigor.bsky.social socks for me, toddler PPE for my son

Chag sameach!

Congrats, Mark! 🎉🎉

I am incredibly excited and proud to share my first preprint from my postdoc! Thank you to all of the co-authors for all your hard work!
Check out the paper for big insights into plasticity mechanisms in navigation circuits! And surprising motifs for inhibitory synaptic plasticity!

Great read by @alexkwan.bsky.social on how fundamental neuroscience research has paved the way for new drug development.
I’d also highlight orexin’s role in sleep–wake regulation and the upcoming wave of dual orexin receptor antagonists (DORAs) for sleep disorders (& soon agonists for narcolepsy).