Integral Answers

YouTube video by Yuval Noah Harari We All Prefer Fiction Over Truth | Yuval Noah Harari & Rich Roll

Key Point: Fiction/Lies are Cheap.
Truth is complicated, takes time, and resources. Not cheap.

youtu.be/pZ5R-e5Ie3Y?...

Thanks for sharing. Vaccines against HPV infections and related cancers hold the promise a radically decreasing the incidence of both in the future.

14B/ Findings:
Prevalence of HPV 16/18 fell from 28.7% to 6.7% in young women post-vaccine rollout.
Evidence of herd immunity and cross-protection against non-vaccine HPV types.

14A/ Tabrizi et al., Lancet Infect Dis, 2014
Title: Assessment of Herd Immunity and Cross-Protection After a Human Papillomavirus Vaccination Programme in Australia: A Repeat Cross-Sectional Study
Journal: Lancet Infect Dis 14(10):958–966

13B/ Findings:
Effectiveness of the bivalent vaccine was 86%–95% against incident infection with HPV 16/18.
Persistent infection reduction: 90% for HPV 16, 91% for HPV 18.

13A/ Donken et al., Journal of Infectious Diseases, 2018
Title: High Effectiveness of the Bivalent HPV Vaccine Against Incident and Persistent HPV Infections up to 6 Years After Vaccination in Young Dutch Women
Journal: J Infect Dis 217(10):1579–1589

12B/ Findings:
Among females aged 14–19, prevalence of vaccine-type HPV (6, 11, 16, 18) dropped by 64% from 2003–2006 to 2009–2012.

In sexually active girls aged 14–19 who received ≥1 vaccine dose, HPV 16/18 prevalence dropped >90%.

12A/ Markowitz et al., Pediatrics, 2016
Title: Prevalence of HPV After Introduction of the Vaccination Program in the United States
Journal: Pediatrics 137(3): e20151968

11/ Citing this study to claim that HPV vaccines “don’t work” is not just bad science—it’s public health malpractice.

Stay with the evidence. Protect our youth.

Vaccinate early, screen regularly.
#HPV #VaccinesWork #CervicalCancer
@IntegralAnswers

10/ Bottom line:
✅ Vaccines protect against covered HPV types
✅ Older vaccines didn’t cover all high-risk types
✅ Gardasil-9 now covers 9 types causing ~90% of cervical cancers
✅ Screening still matters—even for vaccinated individuals

9/ If you only read this study’s title—or worse, an antivax summary—you might think the vaccine failed.

But the truth?

This is a limited case series, not evidence of widespread failure.

8/ “In contrast, large-scale population studies have shown the opposite:
📉 90%+ reductions in HPV 16/18 infections
📉 Significant drops in HSIL and cervical cancer precursors
📚 Markowitz et al., Pediatrics 2016
📚 Donken et al., JID 2018
📚 Tabrizi et al., Lancet ID 2014”

7/ There’s no evidence these women were HPV-negative at time of vaccination.

No screening history was available.

So this study can’t show whether vaccination failed—or whether it came too late.

6/ Timing also matters.
Median age at vaccination: 19.3 years.

For HPV vaccines to be most effective, they must be given before sexual debut (ideally age 9–14).

Some of these patients were likely already infected before vaccination.

5/ The authors admit:

“No standardized research protocol… incomplete vaccination info… no confirmation of full series.”

That’s a polite way of saying: this is a retrospective convenience sample with no statistical power.

4/ Only 5 of the 19 patients had HPV-16, which is targeted by both Cervarix and Gardasil.

Most of the others had types only covered by Gardasil-9, which was introduced later in 2016.

Conclusion? Newer vaccines would’ve helped some of these patients.

3/ Most lesions were caused by HPV types NOT covered by the older vaccines (e.g. types 31, 33, 35, 53, 59, 67, 82).

This is not evidence of vaccine failure—it’s evidence that the vaccine can’t protect against what it wasn’t designed for.

2/🧪 The study looked at just 19 vaccinated patients out of 1,276 referrals between 2011–2017.

No control group. No verification of vaccination dose/timing. No baseline screening. No data on sexual debut or HPV status at time of vaccination.
⚠️ High risk of bias.

1/A 2020 study from a dysplasia referral center in Germany reported 19 cases of high-grade cervical lesions (HSIL) in women who had previously received an HPV vaccine.

Antivaxxers cite it as proof that “HPV vaccines don’t work.”

Here’s why that’s wrong.

THREAD 🧵 | Did HPV vaccines fail? Not quite. Let’s examine what this small German study actually shows—and more importantly, what it doesn’t.
📄 Fischer et al., 2020 | Eur J Gynaecol Oncol

Debunker’s Lesson #1:
Brandolini’s Law

11/ References:
• WHO: www.who.int/health-topic...
• CDC: www.cdc.gov/health-dispa...
• Braveman et al. (2011). Ann Rev Public Health: www.annualreviews.org/content/jour...
• Chetty et al. (2016). JAMA: jamanetwork.com/journals/jam...

10/ Conclusion

We don’t need more pills.

We need more justice.

If we ignore the Social Determinants of Health, we guarantee worse outcomes—no matter who’s president.

Let’s elect leaders who invest in health, not just headlines.

@IntegralAnswers

9/ Climate & Environmental Health

Climate change is a health threat:

Heat deaths. Wildfires. Floods.

✅ U.S. Fix:
•Climate-resilient housing
•Clean energy jobs
•National heat strategy

#SocialDeterminants

8/ Racism & Systemic Inequality

Racism is a public health crisis.

Black Americans face worse outcomes across the board.

✅ U.S. Fix:
•Reduce racial policing disparities
•Fund anti-discrimination policies
•Support reparations legislation

7/ Social & Community Context

Loneliness, violence, discrimination = poor health outcomes.

✅ U.S. Fix:
•Fund local mental health clinics
•Support nonprofits
•Enforce civil rights

#SocialDeterminants

6/ Food Access & Nutrition

Poor nutrition drives chronic illness.

RFK promotes snake oil. The admin underfunds food access.

✅ U.S. Fix:
•Expand SNAP & WIC
•Support urban farms
•End food deserts

#SocialDeterminants

5/ Neighborhood & Built Environment

Your ZIP code > your genetic code.

Pollution, lead, poor housing = shorter life.

✅ U.S. Fix:
•Replace lead pipes
•Expand transit
•Enforce clean air laws

#BuiltEnvironment

4/ Health Care Access & Quality

No insurance = more death.

RFK erodes trust. The admin under-delivers.

✅ U.S. Fix:
•Expand Medicaid
•Cap costs
•Rural and preventive care

#SocialDeterminants

3/ Education Access & Quality

Schooling = life expectancy.

RFK & MAGA attack public ed & science curriculum.

✅ U.S. Fix:
•Universal pre-K
•Fund public schools
•Science-based curricula

#SocialDeterminants