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Gaia Trincucci

@gaiajexpmed.bsky.social

Deputy Editor at Journal of Experimental Medicine, interested in host-pathogen interaction, innate immunity and beyond. Opinions are my own.

519 Followers  |  633 Following  |  19 Posts  |  Joined: 01.01.2025
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Posts by Gaia Trincucci (@gaiajexpmed.bsky.social)

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Sticky memories of an activated #macrophage. Luca Frosio and Renato Ostuni @ostunilab.bsky.social @unisr.bsky.social discuss new findings by Gorin et al. (rupress.org/jem/article/...) in Insights: rupress.org/jem/article/...

#InnateImmunity #inflammation

25.02.2026 20:45 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Welcome to @jem.org!

15.01.2026 21:36 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Welcome to @jem.org!

15.01.2026 21:36 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Neutrophils preserve energy storage in sympathetically activated adipocytes - Nature Neutrophil-derived IL-1Ξ² has a role in preserving lipid stores during metabolic stress.

Today’s #JEMjc @jem.org highlights the work of Alan Saltiel & colleagues @nature.com reporting the role of neutrophil-derived IL-1Ξ² in preserving lipid stores during metabolic stress.

www.nature.com/articles/s41...

21.12.2025 18:10 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Site-specific regulation of Th2 differentiation within lymph node microenvironments | Journal of Experimental Medicine | Rockefeller University Press The authors show that early Th2 cell differentiation is driven via prolonged T–DC macro-clustering in lymph nodes and occurs in a skin site-specific manner

Today's #JEMSpotlight @jem.org highlights the work of Michael Gerner & colleagues investigating early Th2 differentiation in lymph nodes after cutaneous allergen administration with quantitative imaging πŸ“Έ

rupress.org/jem/article/...

21.12.2025 17:51 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS 1. Sera from individuals acutely ill with lobar pneumonia possess the capacity to precipitate in high titre a non-protein somatic fraction derived from pne

#JEMLegacy @jem.org goes back to 1930 with the first description by William Tillett and Thomas Francis Jr. of C-reactive protein (CRP) in the sera of patients during the acute phase of pneumococcal pneumonia.

@RockUPress @RockefellerUniv

rupress.org/jem/article/...

21.12.2025 17:40 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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This #JEMLegacy tweet highlights two papers from 1965 by Drs. Phil Gold and Samuel O. Freedman @mcgill.ca on the discovery of the Carcinoembryonic Antigen (CEA), the basis for the widely used CEA blood test.
rupress.org/jem/article/...
rupress.org/jem/article/...

#cancer #biomarker #CEA

02.10.2025 18:45 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine

06.10.2025 11:21 β€” πŸ‘ 154    πŸ” 72    πŸ’¬ 2    πŸ“Œ 12

Wonderful symposium & location!
Happy to chat! πŸ™‹β€β™€οΈ

01.10.2025 09:35 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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What a fantastic day to start the Immunobiology of #PRRs Symposium in beautiful Lausanne! Much looking forward to being part of an amazing line up of speakers, & to presenting a brand new story on a 100-year old protein whose function remains poorly understood! πŸ˜‰

01.10.2025 07:01 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Excited to be part of this Women in STEM Viepoint 🌟 Huge thanks to @jem.org for the invite - what an inspiring lineup!

18.09.2025 16:28 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0

Another wonderful lineup of #WomeninSTEM for this @jem.org Viewpoint series!

18.09.2025 11:19 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Thank you @jem.org for the invite to participate in this Viewpoint alongside such inspiring scientists 🀩🀩

17.09.2025 19:36 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 2    πŸ“Œ 0

πŸ“£ Journal Editors at EMDS2025:Scotland Edition

@gaiajexpmed.bsky.social, Deputy Editor @jem.org, will be in Edinburgh at #EMDS2025 next week. Reach out to her to discuss your work. Also, check out the Special Collection @jem.org on #macrophage & #dendriticcells

@efis-immunology.bsky.social

12.09.2025 06:51 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Attending #EMDS2025 (@emds2025.bsky.social) in Edinburgh and want to learn about publishing with JEM? πŸ”¬ ✏️ πŸ“„ Meet our Deputy Editor Gaia Trincucci (@gaiajexpmed.bsky.social) who will be there and chat about your research!
πŸ“¨ Connect with Gaia via email: rupress.org/jem/pages/ed...

12.09.2025 10:30 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

New insights from @quintanalabhms.bsky.social @jem.org

26.08.2025 00:12 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Happy to get to contribute to this perspective in JEM!

15.08.2025 17:37 β€” πŸ‘ 31    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0

I had fun thinking about this and reading the advice from other women that I really respect! Thank you @jem.org for the opportunity.

Find your people and do science with your friends

14.08.2025 02:16 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Scripps Research Assistant Professor Alejandra Mendoza (@thepenkpanther.bsky.social) was recently featured in @jem.org’s β€˜Women in STEM’ series alongside other scientists to share her journey and advice on fostering an environment where great science can thrive.

Read more: ow.ly/rFeI50WEbC7

12.08.2025 16:41 β€” πŸ‘ 9    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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New review from Venkatesh and Fong @fredhutch.bsky.social describes how tumor-reactive CD4 T cells are functionally impaired in #cancer, including similarities/differences with CD8 T cells, and how immunotherapies can help overcome this. rupress.org/jem/article/...

#CancerFocus #Immunotherapy

07.08.2025 16:15 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Early and opposing #neutrophil and CD4 T cell responses shape pulmonary #tuberculosis pathology, say Benjamin Gern @bengern.bsky.social, Michael Gerner, Kevin Urdahl et al. rupress.org/jem/article/...

#TB

06.08.2025 18:25 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Attending #Cytokines2025? Are you a grad student or an early career postdoc? Don't miss the opportunity to apply to the @jem.org Early Career Travel Award!

More hereπŸ‘‰ hubs.la/Q03yQFLq0

29.07.2025 16:51 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Quite proud of this labor of love!
Humans are exposed to fungi, inhaling hundred/thousands of spores daily. Immunocompromised patients (chemo, transplant) are at risk for certain fungal infections. But, what about people who don't have these risk factors? This enigma has peppered the literature...

16.06.2025 21:54 β€” πŸ‘ 18    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0

Looking forward attending EACR2025! Happy to chat! πŸ™‹β€β™€οΈ

16.06.2025 08:04 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints
Original paper: https://rupress.org/jem/article/222/7/e20231882/277976/IRF7-controls-spontaneous-autoimmune-germinalVideo summary by Adam Fike (Pennsylvania ... IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints

πŸŽ₯ New video summary of the study "IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints" from Adam Fike, Ziaur Rahman @spt-gc.bsky.social‬ and colleagues (rupress.org/jem/article/...) πŸ‘‡

youtu.be/h_ADv6ncups

09.06.2025 17:53 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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New review from Reglero Real, Rolas, and Nourshargh explores how #aging alters the microvasculature and surrounding stromal cells, disrupting immune cell trafficking and promoting chronic #inflammation. rupress.org/jem/article/...

02.06.2025 16:15 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Attending @keystonesymposia.bsky.social‬''s on #Neuroimmunology and #Neurodegeneration? Meet our Sr. Scientific Editor Lucie Van Emmenis! @lucie-jexpmed.bsky.social will be participating in Meet the Editors session πŸ—“οΈ Tues. June 10, 3:30pm – 4:30pm!

See our collection πŸ‘‰ rupress.org/jem/collecti...

06.06.2025 15:31 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 1    πŸ“Œ 1
DNGR-1 regulates proliferation and migration of bone marrow dendritic cell progenitors | Journal of Experimental Medicine | Rockefeller University Press Cardoso et al. show that DNGR-1–deficient pre-cDCs display cell-intrinsic alterations in their ability to colonize peripheral organs. Their findings highli

#WeekendRead #LocationLocationLocation#MoreThanCrossPresentation! @reisesousalab.bsky.social, Cardoso &co show @jexmed.bsky.social that DNGR1 other than enabling crosspresentation by cDC1s limits seeding of pre-DCs in peripheral tissues, but determines their proper localization in the periphery!

24.05.2025 16:42 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
β€œWhat’s in a name?” Clarifying the identity of RORΞ³t+ antigen-presenting cells | Journal of Experimental Medicine | Rockefeller University Press Sun et al. highlight eTACs as a key component in the group of RORΞ³t+ antigen-presenting cells acting in the induction of RORΞ³t+ pTregs specific to food ant

Great piece in @jem.org by Ken Murphy's group on RORΞ³t APCs in peripheral Treg induction #Immunology

23.05.2025 19:04 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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In our latest #PeopleandIdeas, we speak with Laura Mackay @thedohertyinst.bsky.social about the importance of speaking up (and encouraging others to do so), gaining confidence in your career, and her uncommon introduction to science. rupress.org/jem/article/...

20.05.2025 15:19 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0