Vega Shah

🚀 NEW PANEL ANNOUNCEMENT: Agentic Workflows in Bioinformatics at scverse 2025! 🚀
We're thrilled to introduce an exciting panel discussion at the upcoming scverse Conference 2025!

More information in 🧵

#scverse2025 #Bioinformatics #AgenticAI #Conference

How We Built the First AI-Generated Genomes | Arc Institute Going from designing individual genes to complete genomes is an incredibly challenging problem. We have previously shown that the genomic foundation models like the Evo series can generate single prot...

The first AI-generated microbial genomes by Arc Institute
arcinstitute.org/news/hie-kin...

Pfizer's VP ML Enoch Huang, @broadinstitute.org's @drannecarpenter.bsky.social, Novartis VP Jeremy Jenkins, Formation Bio's Head of Data Sci Enrique Garcia-Rivera & Vertex alum Maria E. Morales r speakers on 9/19 AI panel at Harvard Biotech Club cc @cdbahl.com @dr-alphalyrae.bsky.social Link ⬇️

Congratulations to the team at Ridge Bio, using AI to develop technologies for precision bioconjugation/next gen biotherapeutics 👏

www.businesswire.com/news/home/20...

The expert and VC-led annual report —Decoding Bio Snapshot is out. It was a privilege being a coauthor with several colleagues. Check out our research on the concept of ‘virtual cells’ and future prognosis open.substack.com/pub/decoding...

they did in vitro experiments, looks like fluorescence kinetics assays - data in fig 2

Supervised learning in DNA neural networks - Nature DNA molecules can be programmed to autonomously carry out supervised learning in vitro, with the system learning to perform pattern classification from molecular examples of inputs and desired respons...

Supervised learning in DNA neural networks
www.nature.com/articles/s41...

Applications Now Open for $60,000 NVIDIA Graduate Fellowship Awards The NVIDIA Graduate Fellowship Program provides grants, mentors and technical support to doctoral students doing outstanding research relevant to NVIDIA technologies. The application deadline for the ...

For PhD students in my network, NVIDIA is now accepting applications for our graduate fellowship program. If you are working on topics across AI, life sciences, healthcare and HPC - consider applying.
blogs.nvidia.com/blog/applica...

Giant extrachromosomal element “Inocle” potentially expands the adaptive capacity of the human oral microbiome - Nature Communications This study identified prevalent giant extrachromosomal elements from the human oral microbiome. The genetic and ecological analysis provides insight on the potential contribution of this element in ad...

We are happy to announce that our latest manuscript has been published in Nature Communications! We identified the highly abundant and prevalent (>70% in population) giant (Max. 395kb) extrachromosomal element in the human mouth, named "Inocle".
www.nature.com/articles/s41...

One of the reasons why LLMs won't replace biologists in the foreseeable future, from @dr-alphalyrae.bsky.social's X post today: #medsky #biosky

Parabricks: GPU Accelerated Universal Pan-Instrument Genomics Analysis Software Suite Next-generation sequencing (NGS) has transformed genomics, enabling breakthroughs in biotechnology, healthcare, and pharmaceuticals. However, exponential data growth-outpacing Moore’s Law-presents cri...

Check out the preprint
www.biorxiv.org/content/10.1...

Parabricks, a genomics startup built to GPU-accelerate sequence analysis, was acquired by NVIDIA in 2020. The team has published work showing GPU-accelerated, universal analysis supporting major sequencing platforms: Illumina, Ultima, Singular, MGI, Element Biosciences, PacBio, and Oxford Nanopore.

Everyone working in a STEM field should read this - ‘writing is thinking’
www.nature.com/articles/s44...

Controlled colonization of the human gut with a genetically engineered microbial therapeutic Precision microbiome programming for therapeutic applications is limited by challenges in achieving reproducible colonic colonization. Previously, we created an exclusive niche that we used to engraft...

Controlled colonization of the human gut with a genetically engineered microbial therapeutic | Science www.science.org/doi/10.1126/...

Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence - Nature Communications Researchers used artificial intelligence to mine global venom proteomes and discovered novel peptides with antimicrobial activity. Several candidates showed efficacy against drug-resistant bacteria in...

Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence | Nature Communications
www.nature.com/articles/s41...

This weekend I met some amazing people at the inaugural event of The Knowledge Society in SF. This moment in time feels like a grand experiment in how advanced computing and artificial intelligence will alter humanity. Orgs like TKS are nurturing the next generation of scientists and entrepreneurs!

TechBio Berkeley Meetup · Luma Another TechBio Transformers meetup is coming soon at Fieldwork Brewing in Berkeley. Look forward to seeing folks (returners and newcomers) there!

Another TechBio Berkeley Meetup on the way!
📅 Tues, July 22 | 5:30–7:30 PM
📍 Berkeley, CA (register to see location)

Network with biotech builders, scientists & founders over brews.
RSVP Now: lu.ma/n3boihud

AI & Science Happy Hour · Luma Join FutureHouse and NVIDIA for conversation, food, and drinks with fellow engineers, scientists, and investors. FutureHouse is building an AI scientist that…

We are hosting a community event with FutureHouse for SF Bay Area scientists, engineers and investors! I'll be there with some other colleagues from NVIDIA Digital Biology team. Find us!
lu.ma/py6vsmp9

AI-enabled drug discovery reaches clinical milestone - Nature Medicine A randomized phase 2a clinical trial of an AI-discovered drug and target combination for idiopathic pulmonary fibrosis shows safety and signs of efficacy, marking a concrete step forward in bringing A...

AI-enabled drug discovery reaches clinical milestone | Nature Medicine www.nature.com/articles/s41...

Microbe with bizarrely tiny genome may be evolving into a virus With DNA focused almost entirely on replication, newly discovered organism blurs the line between cells and viruses

Microbe with bizarrely tiny genome may be evolving into a virus www.science.org/content/arti...

TBT San Diego June Meetup · Luma Join TechBio Transformers for our June San Diego meetup! We’ll be discussing all things biology, AI, and the day-to-day life of a scientist. This event…

Our next San Diego meetup is happening on June 26th! Come by for brews and bio chatter! 🧬
lu.ma/r5rkhlrm

Advancing Literature Review & Target Discovery With NVIDIA Biomedical AI-Q Research Agent Blueprint | NVIDIA Technical Blog Biomedical research and drug discovery have long been constrained by labor-intensive processes. In order to kick-off a drug discovery campaign, researchers typically comb through numerous scientific…

The NVIDIA healthcare & life sciences team just dropped a reasoning agent that can review papers, come up with complex hypotheses and then hand off results to a small molecule virtual screening agent. Check out a demo and instructions on how to try it in this tech blog

America is ceding the lead in creating the future The renowned American management consultant and author Peter Drucker is often credited as saying that “the best way to predict the future is to create it”—a view that applies to science as much as to ...

America is ceding the lead in creating the future | Science www.science.org/doi/10.1126/...

@alexr.bsky.social maybe this is the Boltz community you were looking for?: boltz.bio/boltz2

Boltz-2 launched today — Towards Accurate and Efficient Binding Affinity Prediction by MIT and @recursionpharma.bsky.social
boltz.bio/boltz2

new Banksy in Versailles 🩵

TBT Panel: AI for Lab & Regulatory Docs · Luma Join TechBio Transformers and Ganymede Bio for an evening of great food, drinks, and conversation as industry experts explore how AI is driving new levels of…

Join us next week for a panel discussion with Surbhi Sarna, CEO of Collate, Oliver Hesse VP of digital transformation at Bayer and Jack Morel, Product lead a QbDVision. RSVP below - spots are limited 🧬 🧬
lu.ma/8x79mz8f

this is a good list!

there is value to having the ability to manipulate molecules alongside a tool that can query the internet and review publications

ChatGPT can now handle SMILES strings 🧪⚛️