Thierry Galli 🧫🧬🔬🎸🔊 🇪🇺🇫🇷

Kudos to the whole team and @tgalli.bsky.social -- 🙏 for allowing us to collaborate on this super exciting story -- I would also add #stress #organelles -- #ER_literature #proteostasis

#VAMP7-dependent late endosomal #secretion of #ER and #mitochondrial proteins impacts the #tumor #microenvironment and #macrophage engagement
www.nature.com/articles/s41...

The registration deadline for this wonderful meeting is approaching! Be sure to reserve your spot before March 10!

Embryon humain au stade blastocyste prêt à s’implanter. L’enveloppe du noyau des cellules est visible en bleu et le cytosquelette d’actine en orange. © Julie Firmin et Jean-Léon Maître (Institut Curie, Université PSL, CNRS UMR3215, INSERM U934)

Cette image ne vous rappelle-t-elle pas les boules de Noël sur votre sapin ? 😍

C'est avec cette jolie image que l'Inserm vous souhaite un joyeux Noël !🎄

Announcing the #China-#France Joint #Conference on #Neurodegeneration and #Secretion, to be held on March 10-13, 2026, in #Shenzhen.
Inserm #ShenzhenBayLaboratory #ambassadedefranceenchine #institutfrançais
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Entering the USA no more… sorry for all American scientists and friends…

Announcing the #China-#France Joint #Conference on #Neurodegeneration and #Secretion, to be held on March 10-13, 2026, in #Shenzhen.
Inserm #ShenzhenBayLaboratory #ambassadedefranceenchine #institutfrançais
lnkd.in/eygqBe8H
lnkd.in/ee88be-F
lnkd.in/e__7WYTJ

Just Published!

Spatiotemporal Analysis of Glucagon Secretory Granule Dynamics - Ghignoli - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/abs/10.1...

Just Published !

Virion Associated Importin Subunit Beta‐1 Augments Nuclear Import of HIV‐1 Pre‐Integration Complex - Yandrapally - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...

Beyond the Secretory Pathway: New Insights Into Protein Release While proteins bearing N-terminal signal or leader sequences are secreted via the ER-Golgi-plasma membrane axis of the conventional secretion pathway, many cytosolic proteins lacking signaling sequen...

Just Published !

onlinelibrary.wiley.com/doi/10.1111/...

The Role of Small Extracellular Vesicles in Tumor Development and the Prospect of Targeted Therapy Mechanisms of sEV uptake:① Membrane fusion.② Endocytosis.③ Receptor-ligand interaction.

Just Published !

onlinelibrary.wiley.com/doi/10.1111/...

Copper Homeostasis at the Crossroads of Cellular Metabolism, Epigenetic Regulation and Protein Trafficking Copper homeostasis is maintained in the cell by epigenetic regulation, and various metabolic processes. Regulated copper homeostasis balances normal protein trafficking, amino acid metabolism, etc., ...

Just Published !!

onlinelibrary.wiley.com/doi/10.1111/...

The Ecological Transition Conference @ipnp.bsky.social , organized by F Koukouli, MC Angulo, and D Zala, was a great success!

Thank you to Inserm and IPNP for their support, to speakers M Thepin, TB Duong, and HSalmon, and to all participants for the engaging talks!
@inserm.fr

Kickoff of IPNP's retreat! A great opportunity for all the teams to meet, share knowledge, develop collaborations and .... enjoy!

Huge congrats to the team of project "PatCorg" for the prestigious ERC Synergy grant dedicated to studying organoids to uncover mechanisms underlying cortical development: A Pierani (@ipnp.bsky.social), S Nedelec (Institut Monod), S Descroix and B Sorre (Institut Curie), and A Baffet (Inst Curie).

The prestigious Medaille Section Biologie Integrative 2025 from the French Academie des Sciences was awarded to Dr A Pierani @ipnp.bsky.social for her research on the role of Cajal Retzius neurons in cortical development, evolution, and pathologies. Congrats!
@inserm.fr @cnrs.fr

Une époque touche à sa fin pour @ipnp.bsky.social. Elisabeth DAVENAS, notre SG, prend sa retraite. Une grande fête a eu lieu hier soir, remplie de musique (direction artistique T. Galli), de sourires et d'étreintes, et de nombreux mots et gestes de gratitude. @inserm.fr @upcite.bsky.social

Ne sacrifions pas la recherche et l'avenir de la France !
"La recherche d'excellence n'est pas un luxe ; c'est l'investissement vital qui permet de sortir des crises"

www.lesechos.fr/idees-debats...

Explore how #autophagy integrates with neuronal signaling and metabolism at EMBO Workshop "Neuronal autophagy: From circuit function to therapy" in Sant Feliu de Guixols, ES, 17–21 May 2026.

Deadline: 15 Feb

https://meetings.embo.org/event/26-neuronal-autophagy
#EMBONeuronalAutophagy #EMBOevents 🧪

Strain‐Dependent Immune Signaling by Small Extracellular Vesicles Derived From Trypanosoma cruzi‐Infected Macrophages Chagas disease, caused by Trypanosoma cruzi, remains a major treatment challenge due to variations in host immunity and parasite strains. We found that small extracellular vesicles (EVs) from infecte...

Just published !

onlinelibrary.wiley.com/doi/10.1111/...

From Mechanisms to Therapy: Exploring the Role of Ferroptosis in Cervical Cancer Transformation and Treatment This review mainly discusses the role of ferroptosis in cervical cancer from four aspects: underlying mechanisms, stage-specific sensitivity, ferroptosis-related targets and biomarkers, and clinical ...

Just published !

onlinelibrary.wiley.com/doi/10.1111/...

Editors Choice Articles: Traffic Traffic is a cell biology and biochemistry journal devoted to intracellular transport, covering subcellular trafficking, membrane dynamics, organelle function & more.

Editor's selected articles of the last two years onlinelibrary.wiley.com/doi/toc/10.1...

Opinion | Bernie Sanders: Kennedy Must Resign

Bernie Sanders: Kennedy Must Resign www.nytimes.com/2025/08/30/o...

Les aliments ultratransformés ont des effets négatifs forts sur la santé en quelques semaines Dans le cadre d’un essai clinique analogue à ceux qui sont utilisés pour tester les médicaments, des scientifiques ont étudié les impacts sur la santé d’une alimentation riche en aliments ultratransfo...

www.lemonde.fr/planete/arti...

New seminar series! Join us for a talk by Dr D Milovanovic from the German Center for Neurodegenerative Diseases (DZNE), Berlin on 05/09/2025 at noon @ipnp.bsky.social. HOT TOPIC:
Evidence for Lewy Body Pathology as Condensenopathy.
@inserm.fr @upcite.bsky.social #Parkinson #lewybody

CIN85 and CD2AP Are Novel Constituents of Dynamic Tubular Recycling Endosomes That Regulate Recycling Upon Recruitment by MICAL‐L1 In this study, we characterize tubular recycling endosomes and demonstrate that they are dynamic and undergo biogenesis upon CD98 internalization and fission over time. We identify CD2AP and CIN85 as...

Just Published! onlinelibrary.wiley.com/doi/10.1111/...

FGF Signaling Promotes Lysosome Biogenesis in Chondrocytes via the Mannose Phosphate Receptor Pathway FGF signaling regulates lysosomal homeostasis in RCS chondrocytes by inducing TFEB/TFE3 nuclear translocation and activation. This promotes the expression of lysosomal genes and mannose 6-phosphate r....

Just Published ! onlinelibrary.wiley.com/doi/10.1111/...

Pollution aux plastiques : l’appel de la communauté scientifique à combattre un « danger grave et croissant pour la santé » Plusieurs institutions académiques lancent une initiative avec la revue « The Lancet » pour suivre, chaque année, les effets de la pollution plastique sur la santé.

www.lemonde.fr/planete/arti...

✍️ The Jackson/Verbavatz Lab contributed to the publication of a new article
📖 @traffic-journal.bsky.social
📃 Eukaryote-Wide Distribution of a Family of Longin Domain-Containing GAP Complexes for Small GTPases
🔗 onlinelibrary.wiley.com/doi/10.1111/...

Eukaryote‐Wide Distribution of a Family of Longin Domain‐Containing GAP Complexes for Small GTPases The three longin domain-containing GAP complexes - CSW, folliculin, and GATOR1 - have a sporadic but pan-eukaryotic distribution and were likely already present in LECA in some form. Their catalytic ...

Just published! onlinelibrary.wiley.com/doi/10.1111/...