@hesiglobal.bsky.social
HESI is a non-profit institution whose mission is to collaboratively identify and help to resolve global health and environmental challenges through the engagement of scientists from academia, government, industry, NGOs, and other strategic partners.
Reviewers described this work by the HESI Developmental and Reproductive Toxicology (DART) Committee as a โlong overdue contributionโ to the field. Barrow et al., 2026. ๐๐ฑ๐ฒ๐ป๐๐ถ๐ณ๐๐ถ๐ป๐ด ๐ฎ๐ป๐ฑ ๐ฅ๐ฒ๐ฝ๐ผ๐ฟ๐๐ถ๐ป๐ด ๐๐๐๐๐ผ๐ฐ๐ถ๐ฎ ๐ถ๐ป ๐๐ฎ๐ฏ๐ผ๐ฟ๐ฎ๐๐ผ๐ฟ๐ ๐ฅ๐ผ๐ฑ๐ฒ๐ป๐๐. Reproductive Toxicology. https://doi.org/10.1016/j.reprotox.2026.109206
The HESI Global Immuno-Safety Technical Committee is pleased to share their latest publication: โ๐๐๐ ๐ฑ๐ผ๐๐ฒ ๐๐ฒ๐น๐ฒ๐ฐ๐๐ถ๐ผ๐ป ๐ฏ๐ฒ๐๐ผ๐ป๐ฑ ๐ ๐๐๐๐: ๐ข๐ฝ๐๐ถ๐บ๐ถ๐๐ถ๐ป๐ด ๐ฝ๐ต๐ฎ๐๐ฒ ๐ญ ๐ฐ๐น๐ถ๐ป๐ถ๐ฐ๐ฎ๐น ๐๐ฟ๐ถ๐ฎ๐น ๐๐๐ฎ๐ฟ๐๐ถ๐ป๐ด ๐ฑ๐ผ๐๐ฒ ๐๐ต๐ถ๐น๐๐ ๐ฝ๐ฟ๐ผ๐๐ฒ๐ฐ๐๐ถ๐ป๐ด ๐ฝ๐ฎ๐๐ถ๐ฒ๐ป๐ ๐๐ฎ๐ณ๐ฒ๐๐โ in Regulatory Toxicology and Pharmacology. https://doi.org/10.1016/j.yrtph.2026.106038
06.03.2026 12:00 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
๐ข HESI GTTC Professional Development 2026 Award Cycle: Now Open!
๐ Application Deadline: May 15, 2026
Learn more and apply here: https://connect.hesiglobal.org/3bqCXK
#HESI #HESIGlobal #GeneticToxicology #Genomics #Toxicology #ProfessionalDevelopment
Cancer survival is rising, but fertility can be the cost for young patients. Dr. Shuo Xiao is developing ways to protect ovarian function during cancer therapy. See how HESI THRIVE advances oncofertility survivorship science: https://hesithrive.org/2021-awardee-xiao/
04.03.2026 15:00 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
New paper involving HESI Globalโs UVCB Committee: in vitro dosing for difficult-to-test substances & hydrocarbon UVCBs. Tips on dosing options, pitfalls, and exposure verification.
Read: https://doi.org/10.1093/etojnl/vgag044
#HESIGlobal #riskassessment #collaboration
DPICT is HESI Globalโs open database of peer-reviewed clinical in vivo cell-tracking studies of cell therapy products to assess biodistribution and cell fate.
Explore & Submit your studies: https://dpict-celltracking.org/
#HESIGlobal #CellTherapies #Safety #Tracking #Collaboration
HESI Globalโs Genetic Toxicology Technical Committee strengthens interpretation of genetic tox tests for risk-based human health assessment and advances innovative methods. Fact Sheet: https://connect.hesiglobal.org/joRx8o
#HESIGlobal #riskassessment #collaboration
HESI Global GTTC published new evidence to improve nitrosamine (NDSRI) risk evaluation: 79% concordance between Ames & TGR across 33 NDSRIs, supporting stronger science-based decisions that protect patients. https://doi.org/10.1016/j.yrtph.2026.106051 #HESIGlobal #Nitrosamines
25.02.2026 15:00 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
๐ข Join us April 15โ16 for HESI Globalโs Benchmark Dose Modeling webinar! Learn from global experts on BMD in tox, epi, ecotox & moreโand help advance harmonized risk assessment. ๐ Register: https://hesiglobal.org/event/bmd-2026-webinar/
13.02.2026 13:30 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
eSTAR recognizes Dr. Vicky Wang (Univ. of Ottawa) for leading the 2025 FDA Biomarker Qualification Package for TGx-DDI and co-first authoring the Toxicological Sciences paperโadvancing genomic biomarkers for drug safety. #HESIGlobal #eSTAR #TraineeSpotlight #postdoc
06.02.2026 13:00 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
The HESI TEA Committee is reshaping how agrochemical safety is evaluatedโprioritizing human and environmental health while enabling innovation. Learn how they're building smarter, more adaptable risk assessment frameworks: https://connect.hesiglobal.org/k7HhtV #HESIglobal
๐ฌ Experts approved 62 new sequences for the COMPARE Allergen database, using publicly available science to support safe innovation in allergenicity & novel protein safety.
Explore COMPARE 2026 today: https://comparedatabase.org/
๐ฟ Headed to #ICSB2026? Donโt miss โToxicology 101 for Botanicalsโ โ a hands-on short course from the HESI Botanical Safety Consortium!
๐
April 19 | 12โ4pm CT | $15 w/ lunch
๐ Oxford, MS
๐ Register: https://ow.ly/mlpu50XWHww
#HESIglobal #BotanicalSafety
๐ HESI is headed to #2026SOT! Catch our committees in San Diego, March 22โ25, sharing science on NAMs, immuno-safety, botanicals & more. Letโs shape the future of tox together! View HESI Global sessions: https://hesiglobal.org/event/society-of-toxicology-2026-annual-meeting-and-toxexpo/
#HESI
๐ข Join us April 15โ16 for HESI Globalโs Benchmark Dose Modeling webinar! Learn from global experts on BMD in tox, epi, ecotox & moreโand help advance harmonized risk assessment. ๐ Register: https://hesiglobal.org/event/bmd-2026-webinar/
14.01.2026 17:01 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
๐ฑ ๐ The HESI EcoRisk Committee is advancing ecological risk assessment through global collaboration + innovative, non-animal science. Explore their 2025 Fact Sheet to see whatโs new in NAMs, tools, and partnerships: https://connect.hesiglobal.org/ipjiLm
14.01.2026 14:35 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
๐ข The 2025 HESI Global Annual Report is now available!
connect.hesiglobal.org/rmyUFa
๐จ New from #OASISConsortium + #HESIGlobal:
Multi-omics + Cell Painting = the future of chemical safety
๐ doi.org/10.1093/toxs...
#NAMs #Toxicology #AltMethods #HumanHealth #ChemicalSafety #SustainableScience #BroadInstitute
The Sept issue of HESI Global Insights is here! ๐ From #FDA and #NIEHS collaborations to global work in toxicology, biomarkers & moreโHESI Global continues to drive science for a safer world.
Read now: hesiglobal.org/hesi-insight...
#HESI #PublicHealth #EnvironmentalScience #Toxicology
New article from the HESI eSTAR Committee shows how transcriptomic points of departure (tPODs) are changing the game for risk assessment and reducing the need for long-term animal testing.
Read more: doi.org/10.1093/toxs...
#HESI #eSTAR #Toxicology #NGRA #Omics #AltMethods
New publication from the HESI Global Cardiac Safety Committee! Human-relevant cardiac models like hiPSC-CMs and engineered tissues offer earlier, more ethical detection of cardiotoxicity in drug development. Read: hesiglobal.org/publication/...
#HESIGlobal #NAMs #CardiacSafety #3Rs #Toxicology
๐จ The August Edition of HESI Global Insights is out now!
Read the full issue here: hesiglobal.org/hesi-insight...
The Omics for Assessing Signatures for Integrated Safety (OASIS) consortium, launched by Broad, @hesiglobal.bsky.social & scientific partners, with @malifesciences.bsky.social support, is sharing data using cell-based omics tools to reduce reliance on animals in drug & agrochemical safety testing.
30.07.2025 18:42 โ ๐ 1 ๐ 1 ๐ฌ 0 ๐ 0
The July 2025 issue of #HESIGlobal Insights is out now!
AI in health, NAMs in immuno-safety, nitrosamines, new publications & more.
Catch up on global science for a safer world.
๐ hesiglobal.org/hesi-insight...
๐ From virtual control groups to smart biodiversity inventoryingโAI is transforming science. Explore real-world case studies, interactive panels, and a collaborative roadmap-building experience at #HESIโs AI and health protection conference, June 4โ5.
Register now: hesiglobal.org/hesiannualme...
Icons representing new approach methodologies and chemical and drug safety testing, in a speech bubble.
SURVEY: New approach methodologies in safety assessment
Are you involved in the development and application of replacement technologies for toxicity testing or submission and assessment of data for regulatory decision making? Help shape our plans for the coming years: nc3rs.org.uk/our-portfoli...
OASIS logo: Omics for Assessing Signatures for Integrated Safety Consortium
Have you invented a liver cell/tissue model? Want to validate it for tox?
You can apply to test your modelโs ability to detect liver toxicity mechanisms-OASIS Consortium will suggest subsets of compounds based on your system's scale; you run yr assay.
Email oasis@hesiglobal.org for more!
pls RT!
๐จ HESI's Environmental Epidemiology Committee is proud to support the new Special Interest Group on Quantitative Bias Analysis (QBA) within ISEE @isee-global.bsky.social. Led by #HESI Co-Chair David Miller, this SIG will promote practical QBA use in environmental health.
๐ ow.ly/qfG550VooZV
๐จ The March HESI Insights is out! From TGx-DDIโs FDA submission to nitrosamine research and cell therapy safetyโdiscover how HESI is shaping science for global health.
๐ hesiglobal.org/hesi-insight...
#HESI #HumanHealth #EnvironmentalHealth
Early-career scientists in cardiac safetyโthis oneโs for you!
Apply for the HESI Early Career Seminar Award:
$500
Present your research in a public webinar
Connect w/experts in tox & pharmacology
Deadline: April 25, 2025
Details hesiglobal.org/cardiac-safe...
#CardiacSafety #EarlyCareerScience