@hesiglobal.bsky.social
HESI is a non-profit institution whose mission is to collaboratively identify and help to resolve global health and environmental challenges through the engagement of scientists from academia, government, industry, NGOs, and other strategic partners.
HESI Global’s Genetic Toxicology Technical Committee strengthens interpretation of genetic tox tests for risk-based human health assessment and advances innovative methods. Fact Sheet: https://connect.hesiglobal.org/joRx8o
#HESIGlobal #riskassessment #collaboration
HESI Global GTTC published new evidence to improve nitrosamine (NDSRI) risk evaluation: 79% concordance between Ames & TGR across 33 NDSRIs, supporting stronger science-based decisions that protect patients. https://doi.org/10.1016/j.yrtph.2026.106051 #HESIGlobal #Nitrosamines
25.02.2026 15:00 — 👍 0 🔁 0 💬 0 📌 0
📢 Join us April 15–16 for HESI Global’s Benchmark Dose Modeling webinar! Learn from global experts on BMD in tox, epi, ecotox & more—and help advance harmonized risk assessment. 🌍 Register: https://hesiglobal.org/event/bmd-2026-webinar/
13.02.2026 13:30 — 👍 0 🔁 0 💬 0 📌 0
eSTAR recognizes Dr. Vicky Wang (Univ. of Ottawa) for leading the 2025 FDA Biomarker Qualification Package for TGx-DDI and co-first authoring the Toxicological Sciences paper—advancing genomic biomarkers for drug safety. #HESIGlobal #eSTAR #TraineeSpotlight #postdoc
06.02.2026 13:00 — 👍 0 🔁 0 💬 0 📌 0
The HESI TEA Committee is reshaping how agrochemical safety is evaluated—prioritizing human and environmental health while enabling innovation. Learn how they're building smarter, more adaptable risk assessment frameworks: https://connect.hesiglobal.org/k7HhtV #HESIglobal
🔬 Experts approved 62 new sequences for the COMPARE Allergen database, using publicly available science to support safe innovation in allergenicity & novel protein safety.
Explore COMPARE 2026 today: https://comparedatabase.org/
🌿 Headed to #ICSB2026? Don’t miss “Toxicology 101 for Botanicals” — a hands-on short course from the HESI Botanical Safety Consortium!
📅 April 19 | 12–4pm CT | $15 w/ lunch
📍 Oxford, MS
🎓 Register: https://ow.ly/mlpu50XWHww
#HESIglobal #BotanicalSafety
🌟 HESI is headed to #2026SOT! Catch our committees in San Diego, March 22–25, sharing science on NAMs, immuno-safety, botanicals & more. Let’s shape the future of tox together! View HESI Global sessions: https://hesiglobal.org/event/society-of-toxicology-2026-annual-meeting-and-toxexpo/
#HESI
📢 Join us April 15–16 for HESI Global’s Benchmark Dose Modeling webinar! Learn from global experts on BMD in tox, epi, ecotox & more—and help advance harmonized risk assessment. 🌍 Register: https://hesiglobal.org/event/bmd-2026-webinar/
14.01.2026 17:01 — 👍 0 🔁 0 💬 0 📌 0
🌱 🌍 The HESI EcoRisk Committee is advancing ecological risk assessment through global collaboration + innovative, non-animal science. Explore their 2025 Fact Sheet to see what’s new in NAMs, tools, and partnerships: https://connect.hesiglobal.org/ipjiLm
14.01.2026 14:35 — 👍 0 🔁 0 💬 0 📌 0
📢 The 2025 HESI Global Annual Report is now available!
connect.hesiglobal.org/rmyUFa
🚨 New from #OASISConsortium + #HESIGlobal:
Multi-omics + Cell Painting = the future of chemical safety
📄 doi.org/10.1093/toxs...
#NAMs #Toxicology #AltMethods #HumanHealth #ChemicalSafety #SustainableScience #BroadInstitute
The Sept issue of HESI Global Insights is here! 🌍 From #FDA and #NIEHS collaborations to global work in toxicology, biomarkers & more—HESI Global continues to drive science for a safer world.
Read now: hesiglobal.org/hesi-insight...
#HESI #PublicHealth #EnvironmentalScience #Toxicology
New article from the HESI eSTAR Committee shows how transcriptomic points of departure (tPODs) are changing the game for risk assessment and reducing the need for long-term animal testing.
Read more: doi.org/10.1093/toxs...
#HESI #eSTAR #Toxicology #NGRA #Omics #AltMethods
New publication from the HESI Global Cardiac Safety Committee! Human-relevant cardiac models like hiPSC-CMs and engineered tissues offer earlier, more ethical detection of cardiotoxicity in drug development. Read: hesiglobal.org/publication/...
#HESIGlobal #NAMs #CardiacSafety #3Rs #Toxicology
🚨 The August Edition of HESI Global Insights is out now!
Read the full issue here: hesiglobal.org/hesi-insight...
The Omics for Assessing Signatures for Integrated Safety (OASIS) consortium, launched by Broad, @hesiglobal.bsky.social & scientific partners, with @malifesciences.bsky.social support, is sharing data using cell-based omics tools to reduce reliance on animals in drug & agrochemical safety testing.
30.07.2025 18:42 — 👍 1 🔁 1 💬 0 📌 0
The July 2025 issue of #HESIGlobal Insights is out now!
AI in health, NAMs in immuno-safety, nitrosamines, new publications & more.
Catch up on global science for a safer world.
🔗 hesiglobal.org/hesi-insight...
🔍 From virtual control groups to smart biodiversity inventorying—AI is transforming science. Explore real-world case studies, interactive panels, and a collaborative roadmap-building experience at #HESI’s AI and health protection conference, June 4–5.
Register now: hesiglobal.org/hesiannualme...
Icons representing new approach methodologies and chemical and drug safety testing, in a speech bubble.
SURVEY: New approach methodologies in safety assessment
Are you involved in the development and application of replacement technologies for toxicity testing or submission and assessment of data for regulatory decision making? Help shape our plans for the coming years: nc3rs.org.uk/our-portfoli...
OASIS logo: Omics for Assessing Signatures for Integrated Safety Consortium
Have you invented a liver cell/tissue model? Want to validate it for tox?
You can apply to test your model’s ability to detect liver toxicity mechanisms-OASIS Consortium will suggest subsets of compounds based on your system's scale; you run yr assay.
Email oasis@hesiglobal.org for more!
pls RT!
🚨 HESI's Environmental Epidemiology Committee is proud to support the new Special Interest Group on Quantitative Bias Analysis (QBA) within ISEE @isee-global.bsky.social. Led by #HESI Co-Chair David Miller, this SIG will promote practical QBA use in environmental health.
🔗 ow.ly/qfG550VooZV
🚨 The March HESI Insights is out! From TGx-DDI’s FDA submission to nitrosamine research and cell therapy safety—discover how HESI is shaping science for global health.
🔗 hesiglobal.org/hesi-insight...
#HESI #HumanHealth #EnvironmentalHealth
Early-career scientists in cardiac safety—this one’s for you!
Apply for the HESI Early Career Seminar Award:
$500
Present your research in a public webinar
Connect w/experts in tox & pharmacology
Deadline: April 25, 2025
Details hesiglobal.org/cardiac-safe...
#CardiacSafety #EarlyCareerScience
Looking to Network with Scientists in the DC Area?
Register now for an opportunity to network with employers, job seekers, and colleagues seeking to expand their professional connections! #Networking #Science #DCScientists #Toxicology #RegulatoryScience
hesiglobal.org/event/hesi-n...
Image of the job posting (see URL for full text instead)
We've a postdoc opening for our lab at the Broad: Cambridge MA!
Must have experience in toxicology + data science
Work on the wonderful OASIS dataset we are producing... Cell Painting, transcriptomics, proteomics in various liver cell and tissue models!
broad.io/mlcbpostdoc
Save the Date! We are excited to announce the HESI Biannual Meeting, taking place on June 4–5, 2025, in Washington, DC! Join us in shaping the future of science and health through collaboration, innovation, and AI-driven solutions!
Learn More and Stay Updated: hesiglobal.org/hesiannualme...