Absea Biotech

The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity‐Induced Oocyte Maturation Arrest Simulated microgravity induces distinct mitochondrial hyperactivation patterns-elevated OXPHOS and MMP-which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle def...

Study link: doi.org/10.1002/advs...
Authors: Lei Ge, Yuqing Gao, Jian V. Zhang, and colleagues
Published in Advanced Science (2025)

Paper Highlight: A recent study shows that simulated microgravity disrupts oocyte maturation via mitochondrial hyperpolarization, OXPHOS dysregulation, and UPRmt activation. Absea’s anti-HSPD1 antibody supported the analysis of mitochondrial stress responses.

(Link & credit in first comment👇)

Optimized In‐Solution and Gas‐Phase Chemistry Enables High‐Efficiency Interactome Mapping by DSBSO‐Based Cross‐Linking Mass Spectrometry We developed a rapid, high-throughput XL–MS workflow using the enrichable azide-A-DSBSO cross-linker and StageTip-based SCX fractionation. It drastically reduces preparation time and enhances sensiti...

Full paper: doi.org/10.1002/anie... | Congrats Fan Liu (Absea SAB Head, @fmp-berlin.de), Ying Zhu (Absea), & team!

📄 Paper Highlight: Optimized azide-A-DSBSO XL-MS enables proteome-wide interactome mapping with ~10 hr prep & 15× lower sample input. Streamlined workflow, SCX StageTip fractionation, and FAIMS + HCD improve detection & sensitivity, supporting detailed protein interaction studies.

(Link & credit👇)

Cytokeratins do a lot of the heavy lifting in mapping epithelial lineage and figuring out tumor origin.

CK7/CK20, pan-CK, and CK5/6/8/18/19 are staples in many research workflows.

Absea offer now validated CK antibodies, tested across assays and tissues for reproducibility.
🔗 www.absea.bio

Great joining the 10th Anniversary Forum of the JNJ Hospital–NKI Collaboration in Shanghai.
Always energizing to meet researchers from China, the Netherlands, and beyond and hear what they’re working on.
Our CEO shared Absea’s #proteomics tools and discussed supporting reproducible, precise assays.

Study link: www.nature.com/articles/s41...

Authors: @savitski-lab.bsky.social (embl.org , Absea SAB), Clement M. Potel (Absea Associate Director, Proteomics; former embl.org scientist), and collaborators

Published in @natsmb.nature.com.

Congratulations to the team!

📄 Paper Highlight: ~100× faster HT-PELSA enables proteome-wide mapping of protein–ligand interactions in cells, tissues, and bacteria, with peptide-level binding site resolution and off-target detection, supporting applications in proteomics and drug discovery. (Study link & credit in first comment)

📩 Contact us: info@abseabio.com
🌐 Learn more: www.absea.bio

Parkinson’s disease is rising with aging populations, highlighting the need for reliable biomarkers.

For researchers studying PD, Absea developed validated reagents for α-synuclein, LRRK2, DJ-1, PINK1 & Parkin to help advance assay development and biomarker research.

Get in contact with us 👇

- Validation data behind Absea’s #neuroscience:
www.absea.bio/product-anti...

- Performed by Fornasiero Laboratory, University of Göttingen (UMG):
www.fornasierolab.uni-goettingen.de

Get in touch directly to discuss your needs and potential collaborations: info@abseabio.com

Working on neural IF?

We’ve been developing #antibodies with careful epitope choices to help with tissue penetration and background issues.
Recently the Fornasiero Laboratory (U. Göttingen - UMG) validated 85 of them.

Results? High specificity and low background in rat neurons.

See the data 👇

Halfway through #HUPO2025 in Toronto.

Philip and Clément have been exchanging ideas with peers on protein standards, ¹⁵N-labeled proteins, workflows, reproducibility, and more.

There’s still a chance to catch them at Booth 204!

#Proteomics #teammassspec

Day 1 at #HUPO2025 in Toronto.

Philip (SVP) and Clément (Associate Director, Proteomics) are already talking with peers about recombinant proteins, antibodies, proteome libraries, and ¹⁵N-labeled proteins — with a focus on reproducibility in #proteomics.

DM us or find them at Booth #204!

🧪 Reproducible IP starts with reliable reagents.

Absea® Anti-HA beads (MB-301) — benchmarked vs top brands by IP-WB and IP-MS:
• capture comparable
• cleaner elutions, less antibody carryover
• ~10% higher target:total iBAQ.

Connect with us for data & protocols.

#Proteomics #IPMS

Absea will be in Toronto for HUPO 2025 (Nov 9–13)!

Philip (SVP) and Clément (Assoc. Dir., Proteomics) will be at Booth 204 to connect with peers and share insights on proteomics workflows.

If you’re attending, stop by or DM to schedule a chat!

#HUPO2025 #Proteomics

Great to be in Vienna for BIO-Europe 2025.

Philip (SVP) and Crystal (Sales & Product Spec) from Absea are connecting with peers across biotech to share insights and discuss new collaboration opportunities.

If you’re attending and would like to connect, our DMs are open!

#BIOEurope

Autoantibodies (p53, SOX2, NY-ESO-1, MAGE) can appear early and persist — the immune system’s first signal of cancer.

Absea now provides high-purity human recombinant proteins with batch stability and strict quality control, supporting assay development & validation.

Message us: info@abseabio.com

Absea will be in Vienna for #BIOEurope, Nov 3–5.

Our SVP and Sales & Product Spec will take part in discussions across the biotech value chain, focusing on collaboration and research impact.

If you're attending let's connect! We still have a few 1:1 meeting slots available — DMs open.

🔬 Meet Marco Hennrich, our Senior Scientist at Absea!

🎓PhD from @utrechtuniversity.bsky.social

He builds integrated platforms for life sciences ✅
Turning complex biology into reproducible insights
From aging stem cells to lipid transport proteins, Marco makes science clear 👏
#Proteomics

Want to see IP-MS validation results or protocol details?
We’re happy to share!
Message us or check out Pullroven® on Absea’s site: www.absea.bio/index.html

🔬 In PROTAC and molecular-glue research, verifying mechanism of action is essential to confirm E3 recruitment.

Absea’s Pullroven® IP-MS-validated E3 antibodies deliver mass-spec-grade readouts of E3 enrichment for confident mechanistic validation.

#PROTAC #TPD

CNHUPO 2025 is underway in Guangzhou!

Our SVP Philip Lössl and Marketing Dir. Joy Zhou are meeting peers, including @fan-liu.bsky.social(Absea SAB), and following inspiring sessions across the proteomics community.

Great to see Absea featured in @mannlab.bsky.social. presentation.

#teammassspec

A standardized framework for circulating blood proteomics - Nature Genetics The field of blood proteomics faces an upsurge of data with the challenge of cross-study comparisons. This Perspective offers an in-depth analysis and proposes reference materials to enhance data integration and accelerate clinical translation.

Papers & contact:

@natgenet.nature.com perspective: www.nature.com/articles/s41...

Molecular and Cellular Proteomics research: www.mcponline.org/article/S153....

Interested in using N15? info@abseabio.com

New in @natgenet.nature.com: “A standardized framework for circulating blood proteomics” — co-authored by our SVP, Philip Lössl.
Recommends pooled plasma refs + isotope-labeled protein spike-ins.

Thoughts on adoption?

Learn more about👇

#Proteomics #15N #teammassspec

Day 1 at the Westlake Symposium for AI Proteomics & Virtual Cell!

Philip Lössl (our SVP) already chaired a panel — excited to connect with peers and discuss AI-driven proteomics.

Attending? Reach out, we’d love to chat!

#Proteomics #LifeSciences #Ai #teammassspec

Back-to-back proteomics in China.

After Westlake (Oct 8–10), Absea is heading to CNHUPO 2025 in Guangzhou (Oct 11–14).

Philip Lössl (SVP) & Joy Zhou (Marketing Dir.)will represent our team

Looking forward to connecting — DMs open for 1:1s!

#CNHUPO2025 #Proteomics #Biotech #Conference

Source: European Centre for Disease Prevention and Control (12-month Chikungunya virus disease case notification rate per 100 000 population, September 2024-August 2025).