NicolasDSP

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you!

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

With @dudinlab.bsky.social
@embl.org @biology-unige.bsky.social @moorefound.bsky.social

07.08.2025 18:12 — 👍 103    🔁 54    💬 1    📌 2

Join our crazy beautiful project of ExM Atlas !
One more position to fill, this time for a Research Technician at @embl.org in @gautamdey.bsky.social lab.

Come have fun with us !.

07.08.2025 18:22 — 👍 22    🔁 13    💬 0    📌 1

🚨 New EMBO Practical Course!
Ultrastructure Expansion Microscopy: From Cells to Tissue 🔬
📅 20–24 Apr 2026 | 📍 EMBL Heidelberg
Co-organised with @banterlegroup.bsky.social @gautamdey.bsky.social

💡 Register your interest to get notified when registration opens:

🔗 www.embl.org/about/info/c...

21.07.2025 09:07 — 👍 59    🔁 29    💬 1    📌 2

The anticipation is over, the MPM registration and abstract submission is open!!

05.06.2025 17:00 — 👍 10    🔁 4    💬 0    📌 0

Check out our dispatch on apicomplexans that infect corals!

www.sciencedirect.com/science/arti...

These parasite-like partners have lost photosynthesis but retained chlorophyll... are they friend or foe?

@currentbiology.bsky.social #protistsonsky #symbiosky #microsky #coralreefs

13.03.2025 12:11 — 👍 44    🔁 25    💬 3    📌 0

Cryptosporidium modifies intestinal microvilli through an exported virulence factor Cryptosporidium is a common intestinal infection of vertebrates and a significant threat to public health. Within the epithelial layer of the intestine, the parasite invades and replicates. Infected cells are readily detected under the microscope by the presence of elongated microvilli, particularly around the vacuole where the parasite resides. Here, we identify a family of Cryptosporidium virulence factors that are exported into the host cell during infection and localise to the microvilli. We examine the trafficking and function of the most highly expressed family member, MVP1, which appears to control the elongation of microvilli through engagement of host EBP50 and CDC42. Remarkably, this mechanism closely mirrors that of an enteropathogenic Escherichia coli virulence factor, MAP, which is also known to drive host microvilli elongation during infection. This highlights a unique instance where eukaryotic and prokaryotic virulence factors have convergently evolved to modulate host actin structures through a similar mechanism. ### Competing Interest Statement The authors have declared no competing interest.

Cryptosporidium modifies intestinal microvilli through an
exported virulence factor!! Phenomenal work from the newly DR’ed Elena Rodrigues
www.biorxiv.org/content/10.1...

26.02.2025 12:53 — 👍 28    🔁 14    💬 5    📌 1

It's transfection time for Perkinsus marinus and chesapeaki ⚡🦠🧬⚡ Hoping to have some fluorescent parasites in the coming days 🔬 So exciting!! #ProtistOnSky

24.01.2025 18:17 — 👍 5    🔁 0    💬 0    📌 0

Very nice 🤩

09.01.2025 23:18 — 👍 0    🔁 0    💬 0    📌 0

Thanks Omaya! I'm planning to do U-ExM very soon on those cells! 😁🔬

04.01.2025 13:53 — 👍 2    🔁 0    💬 1    📌 0

Dynamic remodeling of centrioles and the microtubule cytoskeleton in the lifecycle of chytrid fungi https://www.biorxiv.org/content/10.1101/2025.01.03.631223v1

04.01.2025 12:31 — 👍 10    🔁 7    💬 0    📌 1

I haven't observed enough cells to confidently conclude about synchronicity just yet 😅. Here's a video of a sporangium where the first division appears asymmetrical. I'm unsure if this is physiological tho... It might just be cell division going wrong !

03.01.2025 19:14 — 👍 3    🔁 0    💬 1    📌 0

Discover the wonders of 𝘗𝘦𝘳𝘬𝘪𝘯𝘴𝘶𝘴 🤩 This parasitic protist undergoes rapid #CellDivision : from a single sporangium to hundreds of motile zoospores. A stunning glimpse into the speed and precision of microbial life! 🌊🔬 Stay tuned for more 𝘗𝘦𝘳𝘬𝘪𝘯𝘴𝘶𝘴 insights! #CellBiology #ProtistsOnSky

02.01.2025 16:33 — 👍 54    🔁 17    💬 2    📌 2

Cambridge colleges 🎄

22.12.2024 19:30 — 👍 1    🔁 0    💬 0    📌 0

𝘗𝘦𝘳𝘬𝘪𝘯𝘴𝘶𝘴 zoospores swimming out of their sporangium 🤩🏊‍♂️

19.12.2024 09:07 — 👍 16    🔁 0    💬 0    📌 0