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Lis Lowe

@lislowe.bsky.social

Scientist, mum, wife. Fan of gut bacteria, mycobacteria, glycans and cazymes. Mannose evangelist. Lowe Lab, NUBI, Newcastle University

1,367 Followers  |  759 Following  |  105 Posts  |  Joined: 25.07.2023
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Posts by Lis Lowe (@lislowe.bsky.social)

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PhD scholarship within biotechnology (296538) | Norwegian University of Life Sciences (NMBU) Job title: PhD scholarship within biotechnology (296538), Employer: Norwegian University of Life Sciences (NMBU), Deadline: Friday, April 3, 2026

PhD position available in our lab at NMBU in πŸ‡³πŸ‡΄ with focus on proteomics, enzyme discovery, applied enzymology and a touch of microbiology🐟πŸ§ͺπŸ§¬πŸ’»πŸ¦  Deadline for applying: April 04, 2026. RTs highly appreciated. For details, see the link below πŸ‘‡
www.jobbnorge.no/en/available...

25.02.2026 14:09 β€” πŸ‘ 0    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Bacteriocin biophysics: From protein-protein interaction models to navigators of the bacterial cell envelope Bacteriocins are toxins deployed by bacteria to kill their competitors. Here, I reflect on my laboratory’s work on protein bacteriocins and their immunity proteins from Gram-negative bacteria. We unco...

A gift of an article from the inimitable Colin Kleanthous as he says a moving farewell to his laboratory. A brave, unrepentant and scientifically brilliant journey is described - please have a read, friends.

www.jbc.org/article/S002...

02.02.2026 12:39 β€” πŸ‘ 66    πŸ” 31    πŸ’¬ 2    πŸ“Œ 1
Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

#Microbiology

The anti-tuberculosis drug bedaquiline targets the mycobacterial ATP synthase, but how that leads to bacterial death is unclear

Here the authors clarify how bedaquiline works

@jnblab.bsky.social @morwan.me
#TBSky #antibiotics #AMR

http://dlvr.it/TQjZ0W

02.02.2026 17:07 β€” πŸ‘ 36    πŸ” 20    πŸ’¬ 3    πŸ“Œ 0

I know what they're getting at with the "could put jobs at risk" but can we focus on the immediate impact? Each suspended round at MRC and BBSRC means about 80 fewer postdoc jobs and the retrospective cuts at MRC add another 30 or so

02.02.2026 17:27 β€” πŸ‘ 10    πŸ” 7    πŸ’¬ 3    πŸ“Œ 0
TAKE A THOUSAND NAKED PICTURES OF YOURSELF NOW. YOU MAY CURRENTLY THINK, "ON I'M TOO SPOOKY OR "NORODY WANTS TO SEE THESE TINY BOOBIES" BUT BEUEVE ME ONE DAY YOU WILL LOOK AT THOSE PICTURES WITH MUCH KINDER EYES AND SAY "DEAR GOD, I WAS A BEAUTIFUL THING!

MORA ROSE

TAKE A THOUSAND NAKED PICTURES OF YOURSELF NOW. YOU MAY CURRENTLY THINK, "ON I'M TOO SPOOKY OR "NORODY WANTS TO SEE THESE TINY BOOBIES" BUT BEUEVE ME ONE DAY YOU WILL LOOK AT THOSE PICTURES WITH MUCH KINDER EYES AND SAY "DEAR GOD, I WAS A BEAUTIFUL THING! MORA ROSE

With much love RIP Catherine O'Hara.

30.01.2026 20:35 β€” πŸ‘ 929    πŸ” 125    πŸ’¬ 13    πŸ“Œ 7
A partially frozen Hudson River

A partially frozen Hudson River

Hudson Freeze #glycotime www.theguardian.com/us-news/vide...

29.01.2026 06:26 β€” πŸ‘ 11    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0

That is such a niche joke and I love it

29.01.2026 09:20 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I am completely baffled by the total lack of any action or any evidence of speaking out from our scientific β€˜leaders’. We’re in a void of information and the consequences are potentially catastrophic- especially as it looks like BBSRC are following suit.

28.01.2026 07:54 β€” πŸ‘ 14    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0

Yeah that’s why I said partly on the mrc website. Bbsrc is just rumours for the time being

23.01.2026 16:41 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ€·β€β™€οΈ

23.01.2026 15:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Partly rumours partly in the mrc website

23.01.2026 15:54 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Not 100% confirmed for bbsrc

23.01.2026 15:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University on FindAPhD.com PhD Project - Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project... interested in bacterial antagonism? PhD opportunity in our team, see below. Please repost!

23.01.2026 10:33 β€” πŸ‘ 22    πŸ” 31    πŸ’¬ 1    πŸ“Œ 2

Bbsrc and mrc grant apps paused until future notice

23.01.2026 15:19 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0
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Research Fellow - Department of Microbes, Infection and Microbiomes - 106849 - Grade 7 To create and contribute to the creation of knowledge by undertaking a specified range of activities as part of an Investigator project funded by Wellcome, focusing on understanding microbial and diet...

Happy New Year – new role! πŸŽ‰

We’re looking for a PostDoc to join us in @halllab.bsky.social @unibirmingham.bsky.social.

Full-time, fixed-term to March 2028. Note tight closing date: 11 Jan 2026. CV + cover letter (submit via portal).

Further details πŸ‘‡

edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

07.01.2026 17:06 β€” πŸ‘ 11    πŸ” 18    πŸ’¬ 1    πŸ“Œ 0

Same to you Luiz, hope you have a fab Christmas!

22.12.2025 19:58 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This looks very very cool, congrats! I’m looking forward to reading when I’m back in the office but it’ll have to wait until 2026! πŸ˜†πŸ₯³

22.12.2025 19:52 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Mycobacterium tuberculosis overcomes phosphate starvation by extensively remodelling its lipidome with phosphorus-free lipids - Nature Communications Here, the authors show that Mycobacterium tuberculosis manipulates lipid metabolism to overcome host restriction, by remodelling its lipidome and utilising host lipids as an alternative phosphate sour...

We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development.

www.nature.com/articles/s41...

A thread.

22.12.2025 13:11 β€” πŸ‘ 95    πŸ” 30    πŸ’¬ 14    πŸ“Œ 3
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Fantastic to have Prof Matthias Wilmanns from EMBL Hamburg hosted by @kshbeckham.bsky.social to give a @mhd-newcastle.bsky.social seminar on mycobacterial infection #dreamtheme

02.12.2025 12:13 β€” πŸ‘ 8    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1
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I Dream of Theresa May – Tara Theatre

Absolutely blown away by the staging and acting at opening night of my play @taratheatre.com last night. Thanks so @natashakchandra.bsky.social and the entire team for transforming it into something special!

Please go see it if you're in London- on until Nov 29th:
taratheatre.com/whats-on/i-d...

18.11.2025 10:00 β€” πŸ‘ 18    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0

Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the β€šwoman in CryoEMβ€˜ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...

18.11.2025 10:18 β€” πŸ‘ 52    πŸ” 40    πŸ’¬ 0    πŸ“Œ 0
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I Dream Of Theresa May: Vivek Nityananda writes about his new play at Tara Theatre, 17 - 29 November 2025 I Dream Of Theresa May: Vivek Nityananda writes about his new play at Tara Theatre, which runs from 17 - 29 November 2025.

I wrote about my play and where it came from for @qxmagazine.bsky.social :

www.qxmagazine.com/2025/11/i-dr...

13.11.2025 15:46 β€” πŸ‘ 13    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
An illustration of a carbonic anhydrase complex in a synthetic mini-carboxysome

An illustration of a carbonic anhydrase complex in a synthetic mini-carboxysome

Pleased to see this collaboration with a great PhD student Pei Cing Ng, from Prof. Luning Liu's lab at Liverpool University published. Structure of the H. neapolitanus carbonic anhydrase and localisation in a mini-carboxysome: www.pnas.org/doi/epdf/10....

13.11.2025 09:57 β€” πŸ‘ 22    πŸ” 11    πŸ’¬ 1    πŸ“Œ 2
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MRC DiMeN Doctoral Training Partnership: Rapid and sensitive diagnostic β€˜fingerprinting’ of prostate cancer O-glycans using Fourier-Transform alternative current voltammetry (FTACV) at University of Y... PhD Project - MRC DiMeN Doctoral Training Partnership: Rapid and sensitive diagnostic ‘fingerprinting’ of prostate cancer O-glycans using Fourier-Transform alternative current voltammetry ...

Funded PhD opportunity for anyone interested in using cutting-edge chemistry to look at glycan profiles in prostate cancer samples πŸ™ŒπŸ»

The successful student will be based at the University of York with Prof Alison Parkin with the opportunity to carry out a placement at the @nucancer.bsky.social

11.11.2025 15:48 β€” πŸ‘ 4    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Excited to share our preprint led by Carlos Voogdt et al

We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...

13.10.2025 07:47 β€” πŸ‘ 85    πŸ” 45    πŸ’¬ 2    πŸ“Œ 4

I’m trying to remember what story Harry was telling to make him laugh like that 🀣🀣

29.09.2025 11:32 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Spending some time collecting memories of Harry today πŸ₯Ί - this is when he was elected a Fellow of the Royal Society. If anyone in the #glycotime universe has pictures or memories of Harry Gilbert they want to share please send them my way πŸ’š

29.09.2025 11:00 β€” πŸ‘ 17    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
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Next up,

Dr Kate Beckham @kshbeckham.bsky.social

The Beckham lab is interested mycobacterial membrane transport processes. They focusing on understanding the steps occurring at the mycobacterial outer membrane.

www.ncl.ac.uk/cbcb/staff/p...

23.09.2025 08:52 β€” πŸ‘ 29    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Day 2 of MHD introductions πŸ˜ƒ

Dr Lis Lowe @lislowe.bsky.social

The Lowe lab is focussed on microbial glycobiology. They work on bacterial Cazymes from commensals and pathogens, and are particularly interested in enzymes that target microbial glycans such as the cell walls of Mycobacteria.

23.09.2025 08:41 β€” πŸ‘ 22    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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Convergent evolution of distinct D-ribulose utilisation pathways in attaching and effacing pathogens - Nature Communications Cottam et al. identify distinct pathways for D-ribulose utilisation in pathogenic Escherichia coli and Citrobacter rodentium, providing mechanistic details and suggesting convergent evolution towards ...

Absolutely delighted to share the labs latest work. We identify and characterise two pathways for D-ribulose utilisation in pathogenic EHEC and Citrobacter.

30.07.2025 09:24 β€” πŸ‘ 34    πŸ” 17    πŸ’¬ 1    πŸ“Œ 1