Lis Lowe

I’m trying to remember what story Harry was telling to make him laugh like that 🤣🤣

Spending some time collecting memories of Harry today 🥺 - this is when he was elected a Fellow of the Royal Society. If anyone in the #glycotime universe has pictures or memories of Harry Gilbert they want to share please send them my way 💚

Next up,

Dr Kate Beckham @kshbeckham.bsky.social

The Beckham lab is interested mycobacterial membrane transport processes. They focusing on understanding the steps occurring at the mycobacterial outer membrane.

www.ncl.ac.uk/cbcb/staff/p...

Day 2 of MHD introductions 😃

Dr Lis Lowe @lislowe.bsky.social

The Lowe lab is focussed on microbial glycobiology. They work on bacterial Cazymes from commensals and pathogens, and are particularly interested in enzymes that target microbial glycans such as the cell walls of Mycobacteria.

Convergent evolution of distinct D-ribulose utilisation pathways in attaching and effacing pathogens - Nature Communications Cottam et al. identify distinct pathways for D-ribulose utilisation in pathogenic Escherichia coli and Citrobacter rodentium, providing mechanistic details and suggesting convergent evolution towards ...

Absolutely delighted to share the labs latest work. We identify and characterise two pathways for D-ribulose utilisation in pathogenic EHEC and Citrobacter.

*JOB AD*: interested in doing a postdoc in microbial metabolomics? Passionate about natural products mass spec?

Come join the group! Informal enquires welcome!

Closing Date: 19 August 2025

jobs.ncl.ac.uk/job/Newcastl...

On the way home from a really great CAZyme GRC. Lots of v interesting talks, a poster prize for Jean-Lou, karaoke, lake swims, beers, catching up with friends, and a lot of responsibility in 2029 when I co-Chair the meeting!

Farewell drinks with this guy. @wragbags.bsky.social we will miss you

Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬
📄 www.biorxiv.org/content/10.1...
🌐 search.foldseek.com/folddisco

A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily Nature Communications - This study reveals that an outer membrane protein from the predator Bdellovibrio bacteriovorus forms a pentameric assembly that traps a lipid monolayer within. This allows...

Learning from bacterial predators on porin-like proteins that trap lipids at rdcu.be/euXWk! Amazing insights by Rebecca J. Parr & Andrew L. Lovering @unibirmingham.bsky.social, and @lalouxlab.bsky.social,‬ as well as all collaborators including Liz Sockett. #MicroSky #predatoryBacteria #porins

Anyway this trans kids book is less than a quid on a place that is definitely not a library but 🤷😑

🦠 NEW VIDEO 🦠

The molecular biology of how Mycobacterium Tuberculosis evades the immune system so well.

Starting with this simulation of a full outer envelope of m.TB--let's explore how the deadliest & most persistent human pathogen completely hacks our immune response. #molecularbiology

In about a week we (Biological Sciences @ Monash Uni in Melbourne, Australia) will be opening a search for 3 (!!!) permanent academic positions (40% research, 40% teaching, 20% service) at Lecturer/Senior Lecturer. 1 Genomics, 2 Ecology. Please share, email me, DM, follow, send carrier pigeons…

The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB): A Large‐Scale Guide to Genetic Conditional Essentiality Mtb transposon sequencing database is a unified resource for exploring conditional gene essentiality in Mycobacterium tuberculosis. By standardizing over 150 transposon sequencing screens, it enables...

Jinich et al. present an important new resource for the Mtb community!
The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB) is an interactive web resource summarizing 150+ published screens.
#MicroSky #Mycobacterium #tuberculosis
onlinelibrary.wiley.com/doi/10.1111/...

#profile update - last full week as an employee at an established certain “Higher Education” institution. Then I just get a vacation until the end of July #itsbeenablast

Two funded Chemistry Masters by Research studentships We want to recruit two enthusiastic and motivated graduates into our multidisciplinary scientific team to develop new data analysis pipelines to monitor obesity in a mouse disease model. Obesity is a ...

GenerationResearch has two fully funded MRes positions (including stipend!) for UK Home students for projects in Chemistry (including structural biology). Applications are due June 19th, and students from underrepresented backgrounds are encouraged to apply. Please share!

Highly recommend these constructive ‘pitch your grant idea’ sessions open to all. A good way for everyone to hear new ideas and how to develop those aims. Always helped along by a supply of cake!

Too cool to be true? 😎 Nope! GlycoShape ReGlyco runs on PyMol through the GlycoMe interface 🥰😍 check out this fab #glycotime tool from Hiren @glyco.me and Ojas @ojas-singh.bsky.social ⤵️🥳🥳🥳🎉🎉

Holy forking shirtballs this Giro has been 🔥🔥🔥

Today’s stage was unbelievable. Couldn’t look away!

Is the UK paying the price for world’s most expensive visas? | The Observer Competing political and economic goals on immigration are resulting in the loss of valuable skills and talent in the UK

“The visa fees are so exceedingly high that it makes coming here very difficult for some people. We are fishing for the best scientists in the world. They want to come and work here because we are such an effective country at science, but if we have these high costs, they can and will go elsewhere.”

Why are prior and concurrent #TB such huge risk factors for M. abscessus infection? #zebrafish preprint lead by our research officer Denise Wee discovers tuberculous granulomas (yellow blob) act as a safe haven for opportunistic mycobacterial pathogens (magenta blobs).

Research Assistant/Associate - Mapping the Bacterial Cell Wall with Super-resolution Microscopy at Newcastle University Apply for the Research Assistant/Associate - Mapping the Bacterial Cell Wall with Super-resolution Microscopy role on jobs.ac.uk, the top job board for academic positions in higher education. View det...

Postdoc position available!

This is a 2-year post funded by the Academy of Medical Sciences. You'll be based in the Centre for Bacterial Cell Biology here in Newcastle, using super-resolution microscopy to look at the bacterial cell wall. 🔬🦠

Please re-post 🙏

www.jobs.ac.uk/job/DMY885/r...

He gave up on the bus and wandered off before I asked

Resisting the urge to ask the guy next to me at the bus stop with a phone in one hand and an iPod in the other what he’s listening to.

Two ERC-funded postdoc positions available in the team - one here and second to follow - please repost! jobs.ncl.ac.uk/job/Newcastl...

This has been a long journey, but it's now out in final form. @kjamali.bsky.social

academic.oup.com/bioinformati...

Oh I think we know who’s is worse 🙇‍♀️

A surface representation of an alphafold protein structure prediction in green with red small projections

Hestu from Zelda breath of the wild game. A green character holding red maracas.

Pretty sure my protein is actually Hestu from Legend of Zelda

A surface representation of an alphafold protein structure prediction in green with red small projections

Hestu from Zelda breath of the wild game. A green character holding red maracas.

Pretty sure my protein is actually Hestu from Legend of Zelda