Eelco Tromer

New work on ARK1 (AURKB?) in Plasmodium (malaria parasite) with @ritatewari.bsky.social and Pushkar Sharma. CPC in Plasmodium is (ofcourse..) different compared to conventional models: two INCENPs, no borealin/survivin - mainly at spindle microtubules/MTOCs. Special thanks to @ryanase.bsky.social!

Pleased to share our new preprint: "Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex". Many thanks to our collaborators.
@ritatewari.bsky.social @eelcotromer.bsky.social @davidguttery.bsky.social

www.biorxiv.org/content/10.1...

Happy to share the first story from my postdoc in @schnittger-lab.bsky.social
We studied TITAN9, a Csm1-like protein in Arabidopsis.
Even though I now work with soil, chromosome segregation and meiosis still have a special place in my heart.
#meiosis4eva #meiosis #chromosomesegregation

Programmed meiotic errors facilitate dichotomous sperm production in the silkworm, Bombyx mori The goal of meiosis is typically to produce haploid gametes (eggs or sperm). Failure to do so is catastrophic for fertility and offspring health. However, Lepidopteran (moths and butterflies) males pr...

So excited to share this preprint from the Rosin lab in collaboration with the Hawley lab and @eelcotromer.bsky.social on moth spermatogenesis! We investigate the meiotic errors that occur during the formation of apyrene sperm (that have no DNA) in silkworms!

www.biorxiv.org/content/10.1...

Postdoc position currently available in our group studying meiosis in arabidopsis and wheat:

www.jic.ac.uk/vacancies/po...

We are growing! A new @zeiss-microscopy.bsky.social widefield tailored for ExM- supported by @moorefound.bsky.social is settling! Another one is on its way at @gautamdey.bsky.social Lab !

These two will become the powerhorses for high-througput imaging of the ExM Atlas of #Microbial Eukaryote !

Happy to see our work published and glad to have contributed together with @maxraas.bsky.social ! Looking forward to all the projects that will come out of this work!

ps. will you bring back taxonomy selection (at least prokaryote/viral/eukaryote?)

much appreciated!

great to see the new version of the webserver - will you bring back jackhmmer? that was such a useful tool for quick checks :)

Ancient co-option of LTR retrotransposons as yeast centromeres The evolutionary origins of the genetic point centromere in the brewer's yeast Saccharomyces cerevisiae, a member of the order Saccharomycetales, are still unknown. Competing hypotheses suggest that t...

It’s out! The evolutionary origins of yeast point centromeres uncovered!

“Ancient co-option of LTR retrotransposons as yeast centromeres”

www.biorxiv.org/content/10.1...

Horizontal acquisition of prokaryotic hopanoid biosynthesis reorganizes membrane physiology driving lifestyle innovation in a eukaryote - Nature Communications Horizontally transferred genes must be integrated into host biology. Here, the authors show that the domestication of bacterial hopanoid synthesis has rewired lipid metabolism of a eukaryote leading t...

OMG IT IS OUT EUKARYOTIC HOPANOIDS DESERVE ALL CAPS

www.nature.com/articles/s41...

I am happy to share a preprint on the marine plankton project I started one year ago (thanks to Julius and Drahomira's help)
www.biorxiv.org/content/10.1...

Chimeric origins and dynamic evolution of central carbon metabolism in eukaryotes Nature Ecology & Evolution - Analysis of the eukaryotic gene repertoires mediating central carbon metabolism identifies ancestral contributions from Alphaproteobacteria, Asgardarchaeota and...

Asgardarchaea & Alphaproteobacteria: key players for the assembly eukaryotic central carbon metabolism! Our new study reveals their gene contributions to glycolysis & TCA cycle, supporting synthrophic scenarios of eukaryogenesis.
rdcu.be/eb0aK

Postdoc Comparative genomics and genome architecture in early-diverging fungi and their protist relatives (3-year position)

Exciting news! I'm looking for a computational biologist to join my lab at Wageningen University & Research! It's a 3-year postdoc position on Holomycota genome architecture and evolution. Spread the word! www.wur.nl/en/vacancy/p...

Have questions about #bioinformatics, #genomics, #evolution or stuck on a project? 🧬💻

I want to help!

Happy to discuss data, figures, writing, academia/industry or chatting just for kicks—no strings attached

Drop questions below, DM, or schedule a meeting

Science together is better than alone 🙌

Shaping up genomes: Prokaryotic roots and eukaryotic diversification of SMC complexes bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Online: our evolutionary interrogation of eukaryotic Structural Maintenance of Chromosomes (SMC) complexes @maxraas.bsky.social @eelcotromer.bsky.social @lauraeme.bsky.social #SMCcomplexes #eukaryogenesis #LECA #condensin #cohesin #evolutionarycellbiology #chromatin 🧵(1/6) doi.org/10.1101/2024...

A new preprint from our group in collaboration with @jvhooff.bsky.social and @eelcotromer.bsky.social. We discovered that trypanosomes have (a zombie of) Bub1-Bub3 despite the fact that tryps do not have a canonical spindle checkpoint! This is a team work involving Dan, WillC, Midori and Patryk