Ali Mohebi

Serotonin drives choice-independent reconfiguration of distributed neural activity Serotonin (5-HT) is a central neuromodulator which is implicated in, amongst other functions, cognitive flexibility. 5-HT is released from the dorsal raphe nucleus (DRN) throughout nearly the entire f...

🚨Pre-print alert🚨

We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭

How is this possible? Strap in! (1/9) 👇🧵

doi.org/10.1101/2025...

A very good read if you want to learn everything there is to know about dopamine. Take a look at chapter 4!
www.sciencedirect.com/handbook/han...

📣 We are expanding! Repost 🙏🏽

- Postdoc (funded by @simonsfoundation.org grant on synchronisation between cognitive representations and stepping)
- Project Associates
- Create your role! (Reach out if you are keen on these topics and these roles do not define you 👀🤗)

www.neuroact.in

Congrats on this milestone of a prolific PhD! I have definitely been inspired and learned a lot from your work on neural processing timescales. Wishing you the best in whatever comes next!

Lovely, congrats!!!

That looks gorgeous, congrats!!!

PC principal best depicts our morally fluid leaders (maybe not leaders but more like admins, and C-suite occupants) in academia. This week, Columbia U got PC principaled.

Which can arguably change the mission and vision of the institution...

A 4/4 Teaching Load Becomes Law at Most of Wisconsin’s Public Universities The mandate, included in the state’s new budget, applies to full-time faculty across the University of Wisconsin system — except at the two R1 universities, where professors must carry 2/2 loads.

Wisconsin edition: double the teaching load (to cut the cost of recruiting/retaining instructors? or what). Bogus construction projects are safe. www.chronicle.com/article/a-4-...

Reading an excellent collection of short stories.... A bit dark though, by design.

Thanks much!!

If you are a student and postdoc interested in body-brain communication - check out Chris's lab!

🚨 Neuro postdocs & grad students: Have a story to tell? Want to practice a talk before a conference or interview? Join our new seminar series on the Isthmus! All are welcome (from around the 🌎). Submit by Aug 20. Share your story (and this ad)!
(Ping me for Qs)
forms.gle/zpSTGWczxjqJ...

It's inevitable, but still makes me sad to see bookstores closing. I noticed one in dt.madcity today. RIP, you church of knowledge and imagination. Your ashes have been scattered all around the weights of some LLM somewhere.

+ trophy hunting

A 4/4 Teaching Load Becomes Law at Most of Wisconsin’s Public Universities The mandate, included in the state’s new budget, applies to full-time faculty across the University of Wisconsin system — except at the two R1 universities, where professors must carry 2/2 loads.

Terrible news: UW system agreed to double most profs’ teaching loads to get their budget. If fully implemented, it could halt research at UW–Madison. Could set a dangerous precedent. Kudos to UW admin.

🔗 www.chronicle.com/article/a-4-...

Excellent. Congrats, Chris!

Planning happy hours! Lots of them :/

Higher dopamine D1 receptor expression in prefrontal parvalbumin neurons underlies higher distractibility in marmosets versus macaques - Communications Biology Integrative anatomical, molecular, behavioral, and modeling evidence suggests that higher dopamine D1 receptor expression in prefrontal cortical parvalbumin neurons in marmosets likely contributes to ...

Textbook neuroscience teaches that anatomy dictates function. But which aspects of anatomy determine differences in function between species? We think neuroscience is now well-placed to tackle this question. Here is our attempt at one piece of the puzzle: www.nature.com/articles/s42...

If these boys are so proud, why do they cover their faces?

NIH-funded science must now be free to read instantly: what you should know US biomedical agency’s public-access policy kicks in on 1 July. Nature talks to specialists about how to comply.

I'm NOT ready to go full Eisen and call for the abolishment/sanction of for-profit journals (yet). However, I believe that to protect taxpayer dollars, the NIH should negotiate a rate for open access fees that is NOT $12,690. Feds can do it.

www.nature.com/articles/d41...

Grace to those who seek peace 🙏

We, the collaterals

Congrats to you, Roberto, and team!

Thanks much. You're right. There isn't much we can do... And yeah, those useless representatives are useless cuz they have long stopped representing us. They have new masters to serve, for a fee.

Eventually, they will run out of bombs.
Mr. Netanyahu and the Ayatollahs will die.
Some of us will survive.
And we will smile and laugh again.
Smile and happiness is the only revenge I have, for these war criminals,
...for stealing the moments.

244 killed, so far.
Me? Going through the existential crisis of wtf I'm doing when my old city is being evacuated, and friends are desperately searching for shelters.

My uncle, along with 14 other family members having a dinner party at his place, died in the 80s during the bombing of Tehran. So please forgive me if I care more about the bombing of my old neighborhood (two blocks from my mom's apartment) than cuts in indirect costs. Apocalypse, Now!

No kings (at least in Madison, WI).

- Look mummy there's an airplane up in the sky.
- Don't worry kid. Mr. Bibi has a good track record of targeted assassination of militants and sparing us.