Flux 🤍🩶💜🖤

Kitty! 😍

In case you want a paper trail.

Knocking and asking WTF!?!????!?
is of course a more moderate branch on the decision tree

redmond.municipal.codes/RMC/6.36.040

🫠

(I have missed rain!)

Ugh. Too damn hot.

Hopefully the worst of it is behind us for this year. 🤞

No lie, this calling campaign is one of the most effective levers we have at the moment.

If we sustain the campaign through the financial quarter we'll be sending a strong message that this administration is bad for business.

Please continue making censorship unprofitable.

PHILLY DA @dalarrykrasner.bsky.social : “Let's not get lost in his silly distraction from the fact that he doesn't want to give up information on his own involvement in a pedophile ring. Did we all forget about that? Trump is the public safety emergency.”

screenshot she sent me today she has a LOT of past due bills but this is the most immediate need it’s so much because her car literally spontaneously exploded over a year ago and since she had gap insurance it paid it off but her insurance has been insanely high since which seems like it should be illegal Dairyland Auto ID card Issuedi Payments due Policy type Auto policy # Payment due Past due Amount due $385.52 Payment status Auto-pay x Off Pay now

my sister harriet a korean woman with black wire glasses kissing her rooster vash the stampede I TOLD HER NEVER KISS HER CHICKENS BECAUSE OF BIRD FLU she said she’ll stop but then this is the pic she sent me today 😭

hi y’all, sorry for all the asks, it’s hard times

my sis harriet is goin thru it & needs help w/ a past due bill $385 💸💕

she works 2 jobs $16/hr but it’s not enough, loves her chicks & said she’ll name a chick after who can support 😂

cash $kungpowchickaa
venmo @healthypersuasion
paypal.me/joajin

alternate Guess Who rules: you can only ask subjective questions like "does your person look like an asshole" or "could you be friends with them"

a third person acts as referee; if they determine your question is too objective, too much resembles a traditional GH query, you lose your turn

If anyone else could help out Marlo (or even just boost signal!), that would be fantastic.

Yeah, I'm reskeeting a lot of requests for help this week. I'd prefer to be sending out memes, cat pictures, art, or talking about this and that.

A lot of people hurting right now; I'm doin what I can. 😮‍💨

Get that tooth taken care of.
When they get bad, they can do a lot of collateral damage.

Correction: the EWG database told me 2 years ago there was uranium in our water, and it doesn't list it for DSM anymore. But it still lists 11 other carcinogens, with one being 369x higher than safe limits. Iowa still gets a shitload of cancer OBVIOUSLY www.thegazette.com/higher-educa...

The 95° heat is supposed to break tomorrow.

(It cannot happen too soon)

Hey, as a librarian I need to tell you:

Our funding depends on usage.

So go ahead and check out that book even if you don't think you'll finish it. No one will know. Check out that DVD even though you might not like it. Get ambitious in your quest for knowledge.

Hey. Do you need a NOPE button?

It goes CLICK CLICK CLICKIT CLICK.

There's a big sparkly one in the thread you can hear.

NOTE: Bree has no legal liability if you take one to work and pavlov your coworkers by vetoing them with the clicker too much.

A murder of crows? You mean caws of death??

So, Becky's car wouldn't start. They need about $450 to cover it. If you were eyeballing their stuff, now's a good time.

I will have their guillotines up shortly to help them.

www.peculiarityshop.com/becky-s-corner

HUGE. The first major court victory involving conditions of confinement at ICE field offices. The judge bars detention in any cell which isn't:

- Restricted by capacity
- Has mats for people to sleep on overnight
- Is cleaned 3 times a day
- Provides hygiene supplies
- Offers free legal calls

Blackwork bug tattoo

Blackwork bug tattoo

Blackwork hognose tattoo

Blackwork jaw forceps tattoo

First four tattoos I have done at Neonwolf Nottingham! Thank you everyone for your trusts!:) (all raw, unedited photoes of freshly done pieces)
Tomorrow 11:00 is still available if you’d like to catch me before I go home!

I've always wondered why the week off exists.

"Yay! You're off BC, here are cramps and bleeding!" - seems rather cruel.

They say to communicate effectively, one method is to mirror the traits of the person you're talking to.

(It can also be a form of vicious mockery - See above)

From my (very) limited understanding this also seems like it would be effective when used by people who are immunocompromised? (as it lures the virus away from human cells)

You always have the best news to share. ♥️

GRAPHICAL ABSTRACT Both sulfated and sialylated glycans present on the cell surface act as co-receptors for the SARS-CoV-2 attachment. Polysialylated and sulfated dendritic polyglycerols are studied for their binding with SARS-CoV-2. In solution, dendritic polyglycerol sialosides (dPGSAs) bind significantly stronger (low nm) to SARS-CoV-2 than their sulfated analogs. dPGSAs effectively inhibit the viral entry into Calu-3 cells.

ABSTRACT Both polysialosides and polysulfates are known to interact with the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. However, a comprehensive site by site analysis of their binding affinities and potential synergistic antiviral effects have not been performed. Here, we report on the synthesis of polysialosides with nanomolar binding affinities to spike proteins of SARS-CoV-2 in solution using microscale thermophoresis. The dendritic polyglycerol based polysialosides dPG500SA0.55 and dPG500SA0.25, with a dissociation constant Kd of 4.78 nm and 10.85 nm, respectively, bind ≥500 times stronger than the high density polysulfated analog dPG500S0.55, to intact SARS-CoV-2 virus particles or isolated spike protein. In fact, the presence of sulfate groups in a heteromultivalent compound dPG500SA0.20S0.20 weakens the binding to spike proteins. A polycarboxylated analog does not bind to SARS-CoV-2, ruling out that the interaction of polysialoside is simply driven by electrostatics. Using explicit-solvent all-atom molecular dynamics simulations and ensemble docking studies, atomistic details are obtained on the interaction of different functional groups with the SARS-CoV-2 RBD. The data support the conclusion that sialosides interact stronger than sulfates for their binding with RBD of SARS-CoV-2. Notably, the most affine binder dPG500SA0.55 inhibits SARS-CoV-2 (WT, D614G) replication up to 98.6% at 0.5 um concentrations.

The discovery is the result of collaboration between Swansea University, Freie Universität Berlin, and Charité-Universitätsmedizin Berlin.

The study has been published in Small. YES, it is PEER-REVIEWED.
• onlinelibrary.wiley.com/doi/10.1002/...

🧪🧵⬇️

John’s lowkey a gay icon for To Wong Foo, he can absolutely make the “has/been” joke. 😂

RFK Jr. in interview with Scripps News: ‘Trusting the experts is not science’ HHS Secretary RFK Jr. sat down with Scripps News for a wide-ranging interview, discussing mRNA vaccine funding policy changes and a recent shooting at the Centers for Disease Control and Prevention.

1. "'Trusting the experts is not a feature of either a science or democracy," Kennedy said."

It's literally a vital feature of both science and of representative democracy.

I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.

three fidget clickers featuring an old-fashioned vintage label that says NOPE across the middle and "absolutely the fuck not" across the top and bottom, with various stars. They sit in a sparkly black base, and when you press them they click!

Hey y'all GUESS WHAT! The NOPE energy is so strong, I'm saying "absolutely the fuck not" in three new colors! Just uploaded a few in teal, pink, and purple over on the shop, as well as a restock on the black & white ones!

thebrokencircle.etsy.com

7,000 Citrix NetScaler Devices Still Vulnerable to CVE-2025-5777 and CVE-2025-6543 A significant number of Citrix NetScaler devices continue to pose serious security risks, with approximately 7,000 systems still vulnerable.

"Citrix NetScaler devices continue to pose serious security risks, with approximately 7,000 systems still vulnerable to two critical exploits that have been added to the Cybersecurity and Infrastructure Security Agency’s Known Exploited Vulnerabilities (KEV) catalog." gbhackers.com/7000-citrix-...

Growing kitteh wants all the fuds.