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Owkin

@owkin.bsky.social

Understand complex biology through agentic AI. Learn more at owkin.com

98 Followers  |  16 Following  |  29 Posts  |  Joined: 09.01.2025
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Posts by Owkin (@owkin.bsky.social)

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Published in Nat Commun: MISO uses local attention transformers to predict spatial gene expression from H&E at near single-cell res. Trained on MOSAIC samples. Outperforms existing methods. In collaboration with FFCD.
Paper: www.nature.com/articles/s41...
Code: github.com/owkin/miso_c...

20.01.2026 15:07 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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We're donating PyDESeq2 to @scverse.bsky.social for long-term maintenance & development. Python reimplementation of DESeq2, ecosystem member since 2023, now in the hands of one of the best open source communities in omics. Good science requires good open source. github.com/scverse/PyDE...

23.12.2025 09:51 โ€” ๐Ÿ‘ 9    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Teaching AI to Reason About Biology: Beyond Facts to Mechanisms | OWKIN How do you teach AI to reason about biology, not just retrieve facts? In 2025, we built the model to do exactly that: ๐Ÿง  OwkinZero: a language model fine-tuned specifically for biological reasoning ๐Ÿ”ฌ...

Our new blog explores OwkinZero, a language model fine-tuned on 300,000+ biological Q&A pairs using RLVR. Compact models that outperform larger commercial models on biological inference. Teaching AI to understand mechanisms: www.linkedin.com/posts/owkin_...

22.12.2025 09:36 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Spatial omics generates rich multimodal data, but extracting biological insights requires infrastructure at scale. Our new blog covers the 2025 data engine. All building toward BASI.

Read more: www.linkedin.com/pulse/buildi...

18.12.2025 09:04 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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We introduce IMILIA: interpretable Multiple Instance Learning for IBD inflammation prediction from H&E WSIs. Combines H0-mini, HistoPLUS, and EpiSeg to automatically derive quantitative inflammatory markers. Preprint on arXiv: arxiv.org/abs/2512.13440

17.12.2025 14:54 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Published in Scientific Reports: SarcNet uses federated AI to forecast metastatic relapse in STS, achieving 0.797 AUC. Dive deeper: www.nature.com/articles/s41...

07.11.2025 09:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Weโ€™re releasing CytoSyn, our new diffusion model for synthetic histopathology image generation. REPA-E architecture. H0-mini conditioning.

Model: huggingface.co/Owkin-Biopti...

Supporting article: www.owkin.com/blogs-case-s...

05.11.2025 10:30 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Discover OKN4395 at #SITC2025โ€”Poster #1169. A triple inhibitor overcoming tumor immunosuppression by targeting EP2, EP4, DP1.

Learn more about OKN4395 at epkin.ai

04.11.2025 09:37 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Our new multimodal ML models achieve high accuracy in predicting iCCA outcomes (c-index 0.70). This collaborative study with @mskcancercenter.bsky.social enhances understanding of the disease and may guide treatment selection.

Check out the paper: www.sciencedirect.com/science/arti...

30.10.2025 15:49 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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We dived into cancer cell interactions with COMPOTES. Using MOSAIC data, we uncovered 45 programs across major cancers, shedding light on immune dynamics and therapeutic paths.

Pre-print at: doi.org/10.1101/2025...

28.10.2025 14:39 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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We used ML & multimodal data to find glioblastoma biomarkers linked to long survival. Our model (AUC 0.85), trained on @ap-hp.bsky.social data, reveals tissue regions predicting survival. Model interpretation & biological insights from MOSAICโ€™s GBM cohort.

Pre-print: www.biorxiv.org/content/10.1...

23.10.2025 14:25 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ“ข New on bioRxiv: We developed SpaMIL, a novel Multiple Instance Learning (MIL) framework for predicting patient-level outcomes from spatial transcriptomics data.

Read the preprint: www.biorxiv.org/content/10.1...

22.10.2025 12:30 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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K Navigator launches on May 6th - introducing the scientific literature tool, K-literature, tailored to scientific research, featuring:

๐Ÿ“‘ 26.5+ million papers
๐Ÿง  Natural language input
๐Ÿ‘ฅ Hallucination limitation

K Navigator is free to use for academic researchers.

www.owkin.com/k-os/owkin-k...

02.04.2025 08:22 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ•น๏ธ How fast can you reach K? Play the game as we get ready to launch K Navigator, a free agentic AI co-pilot boosting the productivity of biology research and breakthroughs across the world.

Try it now:
Google Play โ†’ play.google.com/store/apps/d...
App Store โ†’ apps.apple.com/fr/app/first...

13.03.2025 10:53 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Excited to share our latest research on a novel approach for controlling the sensitivity of whole-slide image classification models in digital pathology, using the TSM (Tile Score Matching) method.

Read the full pre-print: arxiv.org/abs/2502.20144

13.03.2025 09:04 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ’ฅ Owkin K Navigator launches on the 6th of May. Our free-to-use agentic AI co-pilot for researchers across the world, to enhance the productivity of biological research and drive breakthrough discoveries.

Kountdown to K begins now. Sign up here โ†’ www.owkin.com/k-os/owkin-k

06.03.2025 12:38 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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We're launching a comprehensive multimodal patient data discovery program with 20 leading healthcare institutions across France, Spain, Germany, Italy, the US, the UK, and Israel to accelerate medical research by breaking down data silos.

Read more at โ†’ www.owkin.com/newsfeed/owk...

27.02.2025 12:06 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Join us for a webinar, co-hosted with @owkin.bsky.social, on "Harnessing spatial biology & AI to develop targeted therapeutic strategies." Learn how Owkin is using spatial & AI to optimize development of antibody-drug conjugate strategies & generate novel hypotheses: bit.ly/4jVbQZr

18.02.2025 20:00 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Driving innovation in AI for healthcare: Owkin at the AI Action Summit

After an eventful #AIActionSummit, our SVP, Head of Public Affairs & Impact Yedidia Levy-Zauberman unpacks Owkinโ€™s key moments in our latest blog - from a high-impact glioblastoma hackathon to recognition by President Emmanuel Macron.

๐Ÿ“• Read the blog โ†’ www.owkin.com/blogs-case-s...

14.02.2025 10:55 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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A comprehensive evaluation of histopathology foundation models for ovarian cancer subtype classification - npj Precision Oncology npj Precision Oncology - A comprehensive evaluation of histopathology foundation models for ovarian cancer subtype classification

A comprehensive evaluation of histopathology foundation models for ovarian cancer subtype classification www.nature.com/articles/s41... @owkin.bsky.social

08.02.2025 11:36 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Comment lโ€™IA rรฉvolutionne dรฉjร  la lutte contre le cancer Dร‰CRYPTAGE - Lโ€™intelligence artificielle infuse ร  toutes les รฉtapes dans la recherche de nouvelles molรฉcules. Les laboratoires misent dessus pour accรฉlรฉrer la dรฉcouverte et le dรฉveloppement de nouveau...

And Le Figaro reports on the first patient dosed in Owkinโ€™s Phase 1 trial of OKN4395 as well as the results of our Glioblastoma Moonshot Hackathon.

๐Ÿ“ฐ Read Le Figaro article โ†’ www.lefigaro.fr/societes/com...

11.02.2025 09:19 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Pharma Companies Turn to AI to Speed Up Drug Development, But Hit Hurdles Access to data and to skills specific to AI are among the key challenges pharma companies face to unlock the technologyโ€™s potential.

Can AI help Pharma speed up drug development? World Street Journal features our CEO Thomas Clozel alongside Aviv Regev from Genentech, AstraZeneca's Chief Data Scientist Jim Weatherall, and GSK's Senior Director of ML and AI Patrick Schwab.

๐Ÿ“ฐ Read the WSJ article โ†’ www.wsj.com/tech/ai/phar...

11.02.2025 09:19 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Emmanuelle Macron mentions Owkin

Emmanuelle Macron mentions Owkin

Owkin in the news ๐Ÿ‘€ Emmanuelle Macron references Owkinโ€™s work, speaking on Franceโ€™s AI boom ๐Ÿ’ฅ for the #AIActionSummit.

Les Echos dives deeper into Owkinโ€™s mission to redefine healthcare through AI: โ€œAI in healthcare - Franceโ€™s trump cardโ€.

Read more here โ†’ www.lesechos.fr/start-up/eco...

10.02.2025 14:29 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Intelligence artificielle : la France "est dans le train", "est ร  l'heure"
YouTube video by franceinfo Intelligence artificielle : la France "est dans le train", "est ร  l'heure"

France Info also interviews Thomas today about the European AI landscape, and Thomas presents on Owkinโ€™s AI Hackathon for Glioblastoma Research ๐Ÿง , both for the #AIActionSummit.

Watch the interview โ†’ www.youtube.com/watch?v=UCFj...

10.02.2025 13:15 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Yann Le Cun, Joรซlle Barral, Arthur Mensch... Ces sept grandes figures franรงaises de lโ€™intelligence artificielle PORTRAITS - Discrรจtes, ces personnalitรฉs faรงonnent pourtant le monde de demain. Beaucoup dโ€™entre elles ont fait leurs armes au sein des Gafam avant, parfois, de dรฉployer leurs solutions en France. Le ...

Le Figaro features our CEO, Thomas Clozel, as one of the top seven French โญ๏ธs in the AI industry alongside @yann-lecun.bsky.social, Jรฉrรดme Pesenti - Owkin board member - and Luc Julia, creator of Appleโ€™s Siri. ๐Ÿ‘€

Read the article โ†’ www.lefigaro.fr/secteur/high...

10.02.2025 13:15 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
GBM Hackathon

GBM Hackathon

GBM Hackathon

GBM Hackathon

GBM Hackathon

GBM Hackathon

GBM Hackathon

GBM Hackathon

๐Ÿ“ข 4 hours in, 100s of lines of code already written, our Glioblastoma moonshot hackathon is off with a bang. ๐Ÿ’ฅ

Learn more at: www.owkin.com/connect/glio...

#GBM #Hackathon

03.02.2025 14:54 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Spatial Omics vs Outer Spatial Omics comic

Spatial Omics vs Outer Spatial Omics comic

3 days to go until 100 experts meet at Palais Brongniart, Paris, for our AI Moonshot Hackathon in Glioblastoma Research!

Sponsored by Servier and Owkin, with support from AWS, 10x Genomics, Bioptimus, and La Place Fintech.

Learn more: www.owkin.com/connect/glio...

#gbm #neuroskyence #spatialomics

31.01.2025 14:24 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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How AI helps drug developers skirt pharmaโ€™s โ€˜dirty little secretโ€™ Andrew Pierce, senior executive at French biotech Owkin, on how artificial intelligence can make the drug development process more efficient.

Weโ€™re excited to announce the first patient has been dosed in our Phase 1 clinical trial of OKN4395, a first-in-class EP2/EP4/DP1 triple inhibitor for solid tumorsโ .

Learn more in STATโ€™s latest interview with Andrew Pierce, Owkinโ€™s SVP Discovery & Development: www.statnews.com/2025/01/30/o...

30.01.2025 16:38 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Deep learning uncovers histological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients Health sciences; Applied sciences; Machine learning

This study, published by @cp-iscience.bsky.social, was a collaboration with University Hospital Erlangen, Institut Curie, Centre Lรฉon Bรฉrard, Centre Georges-Franรงoisย Leclerc, Stanford University, New York University Langone Medical Center.

๐Ÿ“‘ย Read the full paper here: www.cell.com/iscience/ful...

29.01.2025 10:07 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This model could transform the identification of patients with abnormal Hippo signaling, with the potential to enhance the impact of emerging TEAD inhibitors and set the stage for more effective, personalized cancer therapies.

29.01.2025 10:07 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0