Joan Montero's Avatar

Joan Montero

@joanmontero.bsky.social

Associate Professor at University of Barcelona (Campus Clínic). Leading the Cell death, senescence and cancer precision medicine group. ICREA Acadèmia awardee. Former IBEC/DFCI/HMS. Board member of the SfPM. www.themonterolab.com

151 Followers  |  190 Following  |  27 Posts  |  Joined: 16.11.2024  |  2.0077

Latest posts by joanmontero.bsky.social on Bluesky

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Congratulations @senescel.org for this great meeting! Total success! Dr. Clara Alcon presented our work focused on TIS-mediated resistance, and how to detect it using BH3 profiling and overcome it targeting anti-apoptotic proteins. Can’t wait for the next meeting!

08.11.2025 08:50 — 👍 3    🔁 1    💬 0    📌 1
Seminars | SFPM The SFPM Seminar series is for those interested in the use of assaying technology to further biomarker discovery, drug R&D and personalized healthcare outcomes.

🚨Excited to announce the seminar by Kushtrim Kryeziu, PhD (Oslo University) on "Functional Precision Oncology for Metastatic Colorectal Cancer". Join us TODAY, at 12 PM EDT, open to everyone! Don't miss it and consider joining the SFPM

www.sfpm.io/seminars

08.10.2025 11:11 — 👍 0    🔁 1    💬 0    📌 0
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Aconsegueixen revertir l’alzheimer en ratolins amb l'ús de nanopartícules - Institute for Bioengineering of Catalonia Un equip internacional codirigit per l'Institut de Bioenginyeria de Catalunya (IBEC) i l'Hospital West China de la Universitat de Sichuan (WCHSU) va poder revertir l'Alzheimer en ratolins després de n...

#RecercaUB | 🧠 Un nou estudi aconsegueix revertir els efectes de l’Alzheimer en ratolins amb l’ús de nanopartícules portadores de molècules terapèutiques.

🔬 Hi han participat Lorena Ruiz Pérez, de #FísicaUB, i Giuseppe Battaglia, tots dos membres @ibecbarcelona.eu.

07.10.2025 13:13 — 👍 24    🔁 7    💬 2    📌 1

Congratulations Tony! I wish you every success in this new endeavor and I have no doubt that your vision, leadership and integrity will bring great value to the NCI. I'm deeply grateful for your invaluable mentorship, friendship and encouragement over the years. Amazing news!

30.09.2025 06:09 — 👍 2    🔁 0    💬 0    📌 0
How functional precision medicine could be the future of cancer care | Dr. Diana Azzam | TEDxMiami
YouTube video by TEDx Talks How functional precision medicine could be the future of cancer care | Dr. Diana Azzam | TEDxMiami

A must watch video: How functional precision medicine could be the future of cancer care. Truly inspiring TED talk by Dr. Diana Azzam

www.youtube.com/watch?v=CqLC...

26.08.2025 11:09 — 👍 1    🔁 0    💬 0    📌 0

Moltes felicitats Quim i equip!

22.07.2025 08:38 — 👍 1    🔁 0    💬 0    📌 0

Parece un déja-vu con respecto a la DANA si no fuese porque que en Texas no había nadie para avisar y en Valencia si. Pero ambas desgraciad tienen en común que la incompetencia cuesta vidas

11.07.2025 13:22 — 👍 4    🔁 0    💬 0    📌 0
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Càncer de mama: identifiquen les cèl·lules que actuen com a llavors de la metàstasi Investigadors de l'Hospital del Mar vinculen per primer cop una proteïna a la metàstasi en el càncer de mama i obren la porta a tractaments preventius

Delighted to see good research highlighted on TV @som.3cat.cat
Congratulations @tceliaterrassa.bsky.social and team! Hope your findings help to better treat metastatic breast cancer patients.
www.3cat.cat/324/cancer-d...

11.07.2025 13:16 — 👍 1    🔁 0    💬 0    📌 0

Osti, perquè em dius que es gazpacho però podria ben bé ser crema de pèsols

10.07.2025 20:44 — 👍 1    🔁 0    💬 1    📌 0

This is going to be a really cool meeting with great invited speakers, but also offering the possibility to showcase your work independently of your career stage.
It will also be loads of fun in Barcelona, with the most friendly and welcoming community ☺️
Rush to register at senescel2025.senescel.org

10.07.2025 07:58 — 👍 4    🔁 2    💬 0    📌 0
Seminars | SFPM The SFPM Seminar series is for those interested in the use of assaying technology to further biomarker discovery, drug R&D and personalized healthcare outcomes.

✨ Excited to announce a talk by Rita Fior, PhD on "Zebrafish Avatars for Personalized Medicine & Discovery of Innate Immune Mechanisms"! Join us next Wednesday, July 9, 2025, at 12 PM EDT, organized by @thesfpm.bsky.social. Don't miss it!
www.sfpm.io/seminars

02.07.2025 15:08 — 👍 0    🔁 0    💬 0    📌 0
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Acquired resistance in cancer: towards targeted therapeutic strategies - Nature Reviews Cancer Acquired therapeutic resistance is a key contributor to cancer treatment failure, requiring new approaches to address its complex mechanisms. In this Roadmap, Soragni, Knudsen and colleagues discuss t...

🚨 New Article Alert! Dive into a fantastic review by several @thesfpm.bsky.social members on how new technologies and functional approaches are revolutionizing personalized cancer treatment. Don't miss out on this game-changing insight!

www.nature.com/articles/s41...

27.06.2025 14:44 — 👍 3    🔁 1    💬 0    📌 0

Congratulations Sandra and team! Fantastic work!

28.04.2025 21:52 — 👍 0    🔁 0    💬 0    📌 0
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Online now concurrent with the #AACR25 oral presentation by Cancer Discovery Early Career Award Winner @Sandra_Misale: Direct Inhibition of RAS Reveals the Features of Oncogenic Signaling Driven by RAS G12 and Q61 Mutations doi.org/10.1158/2159...

28.04.2025 18:30 — 👍 10    🔁 1    💬 2    📌 0

Quote of the day: “If you think research is expensive, try disease.” Mary Lasker

15.04.2025 10:15 — 👍 2    🔁 1    💬 0    📌 0
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New advances in the fight against the most common form of lung cancer

Excited to share our latest findings! 🫁 Dynamic BH3 profiling predicts ALK-TKI response in NSCLC, revealing new therapeutic combos to overcome resistance. Read the summary here:

web.ub.edu/en/web/actua...

09.04.2025 09:38 — 👍 6    🔁 0    💬 0    📌 0
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Novel selective strategies targeting the BCL-2 family to enhance clinical efficacy in ALK-rearranged non-small cell lung cancer Cell Death & Disease - Novel selective strategies targeting the BCL-2 family to enhance clinical efficacy in ALK-rearranged non-small cell lung cancer

Excited to share our latest findings! 🫁 Dynamic BH3 profiling predicts ALK-TKI response in NSCLC, revealing new therapeutic combos to overcome resistance. Congratulations to Dr. Martín and to all our collaborators
@ub.edu @ibecbarcelona.eu @hospitalclinic.bsky.social CIBERBBN
rdcu.be/eennu

21.03.2025 08:52 — 👍 1    🔁 0    💬 1    📌 0

Do not miss this great talk tomorrow at 5pm CET (12pm EDT): Zinaida Perova (EMBL) "Leveraging CancerModels.Org: Enhancing Precision Oncology Through Collaborative Cancer Model Resources". @thesfpm.bsky.social

www.sfpm.io/seminars

11.03.2025 11:15 — 👍 1    🔁 1    💬 0    📌 0

Happy International Women’s day to all the brave, intelligent, loving, amazing women worldwide!

08.03.2025 16:36 — 👍 1    🔁 0    💬 0    📌 0
Home | Montero Lab The Montero Lab at the University of Barcelona's Department of Biomedical Sciences is dedicated to exploring the biology of cancer metastasis.

🚀 Exciting news! Our new research lab website is live! 🌐 Explore cutting-edge projects, publications, and more. Visit us at themonterolab.com

13.02.2025 10:40 — 👍 0    🔁 0    💬 0    📌 0
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ApoList – January 2025 Caspases TIR signaling activates caspase-like immunity in bacteria – François Rousset, Ilya Osterman, Tali Scherf, Alla H. Falkovich, Azita Leavitt, Gil Amitai, Sapir Shir, Sergey Malitsky, M…

Papers on cell death from January 2025
Caspases, pyroptosis, apoptosis, cytotoxicity, ferroptosis, necroptosis, Bcl-2 family and more!
ApoList
celldeath.wordpress.com/2025/02/04/a...

04.02.2025 17:31 — 👍 8    🔁 4    💬 0    📌 0

On #WorldCancerDay #WCD2025 and every day, our lab is committed to finding a cure for cancer through groundbreaking research and advanced functional precision medicine. Together, we can find a treatment for each patient and beat cancer @ub.edu @thesfpm.bsky.social

04.02.2025 10:30 — 👍 2    🔁 1    💬 0    📌 0
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Ex vivo venetoclax sensitivity predicts clinical response in acute myeloid leukemia in the prospective VenEx trial Key PointsBlast-specific ex vivo venetoclax sensitivity correlated strongly with treatment responses and predicted longer survival.VenEx trial showed that

An exciting multicenter phase 2 functional precision medicine clinical trial showing how a rapid ex vivo venetoclax sensitivity assay was the strongest predictor for a favorable treatment response and survival in relapsed/refractory secondary AML

ashpublications.org/blood/articl...

29.01.2025 06:45 — 👍 3    🔁 3    💬 0    📌 0

Moltes felicitats a tot l’equip!

22.01.2025 14:02 — 👍 1    🔁 0    💬 0    📌 0
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Descriuen un mecanisme per poder eliminar les cèl·lules perjudicials originades per tractaments oncològics Després de tractar un tumor amb quimioteràpia i radioteràpia, es poden originar unes cèl·lules que es coneixen com a senescents. Són cèl·lules que no es divideixen, estan involucrades en el procés d’envelliment i són resistents a la mort cel·lular, però encara són actives metabòlicament en el cos humà. Quan s’hi acumulen, poden posar en risc la recuperació dels pacients. Ara, una recerca liderada per la UB descriu per primer cop un mecanisme molecular que podria impulsar el disseny d’estratègies per eliminar les cèl·lules senescents en els pacients oncològics.

#RecercaUB | 🔬 Un estudi liderat per la #UniBarcelona descriu un mecanisme per eliminar les cèl·lules perjudicials originades per tractaments oncològics

📷 Dirigeix el treball Joan Montero. La primera autora és Clara Alcon, tots dos de @medicinacs-ub.bsky.social.

👉 web.ub.edu/web/actualit...

22.01.2025 13:49 — 👍 10    🔁 4    💬 0    📌 2

Thrilled to receive the prestigious ICREA Acadèmia award! A heartfelt thank you to everyone at @ub.edu & ICREA - Institució Catalana de Recerca i Estudis Avançats who made this possible.

14.01.2025 14:40 — 👍 1    🔁 0    💬 0    📌 0

We show how melanoma senescent cells become dependent on BCL-xL by downregulating HRK and increasing BCL-xL:BAK binding. This explains why navitoclax is a good senolytic. @ub.edu CampusClinicUB
CIBERBBN @ibecbarcelona.eu Great work by Dr. Clara Alcon!

07.01.2025 15:25 — 👍 1    🔁 0    💬 0    📌 0
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HRK downregulation and augmented BCL-xL binding to BAK confer apoptotic protection to therapy-induced senescent melanoma cells Cell Death & Differentiation - HRK downregulation and augmented BCL-xL binding to BAK confer apoptotic protection to therapy-induced senescent melanoma cells

Proud to share three papers from our lab rdcu.be/d2hUm @ub.edu , Letai lab rdcu.be/d5rb3, and R. Bernards rdcu.be/d5rjW all showing predictable mitochondrial control of senescent cell death, using BH3 profiling as a biomarker for senolytic therapy.

07.01.2025 15:25 — 👍 5    🔁 1    💬 1    📌 0

Buon Natale Ivano!

25.12.2024 13:20 — 👍 1    🔁 0    💬 0    📌 0

Merry Christmas!

24.12.2024 18:18 — 👍 2    🔁 0    💬 1    📌 0

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