Joseph Buxbaum

FDA Launches Framework for Accelerating Development of Individualized Therapies for Ultra-Rare Diseases The U.S. Food and Drug Administration today issued draft guidance for sponsors seeking approval for targeted individualized therapies by generating substantial evidence of effectiveness and safety whe...

www.fda.gov/news-events/...

Nine Principal Investigators Join the SPARK NS Program, 2026 Cohort The nine projects are collectively eligible for up to $18 million in funding and support for drug development.

sparkns.org/news-and-ins... what an amazing opportunity!!

New Documents Reveal a Controversial Vaccine Study's Unusual Path to CDC Approval A new investigation has found irregularities in the ethics review of a grant to study effects of a birth dose of hepatitis B vaccine in Guinea-Bissau.

www.rollingstone.com/politics/pol...

A lot of people, including me, were wondering how an IRB could ever approve this study.

The answer is that no IRB did. The person who “signed off” on approval from the only ethics board that reviewed it had resigned three years earlier. His signature was used without his knowledge.

As Bad Bunny has already said, “Eres Twitero o Presidente”

Your Ring camera can scam passing dogs and compare them to databases of missing dogs and that’s heartwarming and there are absolutely no sinister implications that’s why the guy in the button-down and Dockers is soothing

Paul G. Allen (1953–2018) Cofounder of Microsoft, visionary, and philanthropist

A good moment to remember all that Paul Allen did for science and for Seattle and for the Seahawks !!!

www.science.org/doi/10.1126/...

Is it though? All data visualization involves choices. Here, starting from the first day of an arbitrary annual calendar; a continuous line would show that the beginning of 2026 looks like the latter part of 2025. Sure. But the point is annual cases in, say, 2023 versus the cases in 2026 to date.

Catholic Vice President Vance takes to social media to justify killing of Renee Good After the tragic shooting of Renee Good at the hands of ICE, the Catholic vice president of the United States took to social media to justify the killing.

www.ncronline.org/opinion/ncr-...

Firing of neuroscience institute chief adds to NIH’s leadership vacuum Trump administration declines to renew appointment of Walter Koroshetz, against NIH director’s wishes

President Donald Trump’s administration has declined to reappoint Walter Koroshetz as head of the NIH’s neuroscience institute—even though the agency’s director had backed his renewal. https://scim.ag/4pZD0kq

Peter Thiel says he’ll leave California if they pass a 1% wealth tax on billionaires for five years. So… how much would it take to make him leave the U.S.?

The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine A quiet policy change means the government is making fewer bets on long-term science.

www.nytimes.com/interactive/... 43% fewer grants funded in mental health, 47% fewer grants funded in human genomics/genetics research, and 61% fewer grants funded in minority health.

autismsciencefoundation.org/press_releas...

www.reuters.com/business/hea...

Autism Has 2 Main Genetic Drivers–How Treatments Can Help Three children, one major genetic difference, three different outcomes.

www.theepochtimes.com/health/how-g...

YouTube video by Mount Sinai Health System The Vitals | The Truth About Autism: Causes, Care, and What's Next

A summary of the state of the art in autism; having a great interviewer like Leslie Schlachter makes all of the difference!

www.youtube.com/watch?v=_PQs...

Kentucky official reminds residents they can't vote for New York City mayor Kentucky Secretary of State Michael Adams said his office has received calls about polls being closed in the state.

www.newsweek.com/kentucky-off... and sharing this psa

Social media erupts with laughter, mockery over Kentucky official's obvious election reminder to residents Secretary of State Michael Adams reminded Kentucky voters that 2025 is an off-year with no state elections, even though some states are holding races.

www.foxnews.com/politics/soc... sharing this PSA

In Kyoto for a ceremony for three friends who have been authorized to teach the historic/foundational shakuhachi repertoire. Have been visiting temples, meeting fellow aficionados, hiking on beautiful mountain paths, with more to come. A wonderful way to celebrate a milestone birthday.

m.facebook.com/story.php?st...

giving.mountsinai.org/site/SPageSe...

It’s awkward posting for something nominally in my honor but this is really an event to support the large, dedicated, compassionate and transformative team at the Seaver Autism Center. Please support our wonderful team! And stop by if you can!

This was certainly not the main point of the post :-) but I see your point and will try to check with the church next time I am on the square. Will edit the post.

RFK Jr.’s Inaccurate Claims About Tylenol, Circumcision and Autism - FactCheck.org Health and Human Services Secretary Robert F. Kennedy Jr. further added to the Trump administration’s problematic claims about Tylenol and autism on Oct. 9, alleging during a Cabinet meeting that circ...

www.factcheck.org/2025/10/rfk-...

Close Friend of JD Vance Skirts Normal Channels to Take Over NIH Environmental Health Institute - Inside Climate News Despite a federal hiring freeze, the Trump administration just appointed a scientist who calls Vance one of his “closest friends” to head the nation’s key environmental health research arm.

#TobRegSky #PedSky #MedSky #EpiSky #addictionsci #policysky #polisky 🧪🛟 @altcdc.altgov.info With statements by former NIEHS Director Birnbaum and others.

JD Vance officiated the wedding of new head of NIH environmental institute Unusual hiring process raises fears of political favoritism

If you thought MAHA was going to at least look at environmental risk in an unbiased way. Nope. A close friend of Vance is now head of NIEHS with no process amidst the shutdown: JD Vance officiated the wedding of new head of NIH environmental institute | Science | AAAS www.science.org/content/arti...

The bell in First Congregational Church in Falmouth, MA was forged in 1796 by Paul Revere. It has been rung over 30,000,000 times. Today the congregation rang it especially for the No Kings event.

Nine years ago I was honored to be inducted into the National Academy of Medicine. But the president of NAM has been so muted about the devastating impact of the current administration on health sciences. I look forward to working with Dr Bertagnolli, the incoming president of NAM, from July 2026.