Colby Vorland

Nonsense functional medicine stuff needs WAY more pushback from health professionals. We needed pushback several administrations ago, and now we are here.

In a rationale country, the fact that a surgeon general candidate made any money from selling supplements, let alone $325K in 2 years, should be disqualifying.

😔

I applied to access NHS and HPFS data to only reproduce only a subset of results within one paper and was quoted $50k.

thanks! They have one exposed in their public extension code: github.com/PubPeerFound.... I could not get ahold of them by email, so have assumed it is ok to use (but if they are reading please let me know if not!)

Lazy Scholar is available on Chrome: chromewebstore.google.com/detail/lazy-... and Firefox: addons.mozilla.org/en-US/firefo...

... a validation check of each reference to see that it exists at all in scholarly databases, and self-citation count. Text is automatically screened for fingerprints such as 'tortured phrases', thanks to the Problematic Paper Screener. More coming soon!

Thanks to freely available resources, we can do some research integrity checks automatically, including checking the paper and its references against the
@retractionwatch.com and @pubpeer.com databases ..

I launched version 3.0 of my browser extension "Lazy Scholar", a free in-browser research assistant. It opens automatically when you load an academic article.

See: lazyscholar.org/2026/01/10/l...

Sad to see these revised standards for 'integrative and functional nutrition' coming from RDs in the era of MAHA - a time to critically evaluate, not endorse, this psuedoscientific gish gallop of unvalidated diagnostic tests & handwavey rationale for therapy (mitochondria! toxins! epigenetics!)

Gave some quotes to the @nytimes.com in this piece covering saturated fat in some anticipation of potential rollbacks on these regulations from the Kennedy HHS/Rollins USDA Dietary Guidelines. It's a meaty topic but Dr Callahan covered it well for the general public!

Heh I was looking at this trial this morning too.

Nutrients even has a policy requiring that trials are registered prospectively but don't enforce it. We commented in a letter once noting when one that was against policy and they made us remove that language 🙄

We are proud to feature 2025 RCCN Pilot Awardees David Allison and Colby Vorland in this Pilot Awardee Spotlight! Learn more about their Inter-NIA Center pilot project here: bit.ly/4pvWAEb #Geroscience #Statistics #AgingResearch @colbyvorland.bsky.social

Credit to MDPI for retracting this vitamin D/COVID-19 meta-analysis that @gidmk.bsky.social and I flagged: pubpeer.com/publications...

Some interesting PubPeer comments on "Efficacy of oral folinic acid supplementation in children with autism spectrum disorder: a randomized double-blind, placebo-controlled trial" pubpeer.com/publications...

Column | Continuous glucose monitors are not a silver bullet for public health Continuous glucose monitors can’t single-handedly make you eat better or lose weight.

No, glucose monitors aren't particularly helpful for people who don't have diabetes or pre-diabetes.

Pathologizing insulin spikes is yet another distraction from the reality of an untenable food environment.
www.washingtonpost.com/food/2025/09...

Cinnamon For Diabetes And Vitamin D For COVID-19 The painfully slow process of scientific correction

My new piece is on the painfully slow process of scientific error-correction and how it harms real people all the time.

Also, why cinnamon probably isn't a useful treatment for diabetes.

gidmk.substack.com/p/cinnamon-f...

Drummond Rennie (1936-2025), in his own words Drummond Rennie I first became aware of the work of Drummond Rennie almost by accident: By borrowing his office. It was the summer of 1997, and as a rising fourth-year medical student, I was spendi…

Saddened to hear of the passing of Drummond Rennie, a quite influential figure. retractionwatch.com/2025/09/15/d...

Amazing meeting, already looking forward to the next one!

INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings....

www.medrxiv.org/content/10.1...

INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.

A new expression of concern was published on this randomized clinical trial of cinnamon for diabetes.

The study itself has been cited, according to Google, 1,700 times.

I first complained about it in 2023, so let me tell you the story of one of the most problematic papers I've come across 1/n

Another Asemi paper retracted (retractionwatch.com/2020/11/10/j...)

"Science becomes trustworthy by constantly questioning itself" journals.plos.org/plosbiology/... by @briannosek.bsky.social

Every reputable expert I know considers mRNA vaccine technology to be one of the most revolutionary advances in medicine in our lifetimes. Its inventors won the Nobel Prize in 2023. Shutting it down now is pointless self-harm to humanity.

The PRC program is now online!

Using #GPT to Identify Changes in RCT Outcomes Registered on ClinicalTrials.gov

from @ischoolui.bsky.social @colbyvorland.bsky.social

is part of Day 3’s 'Use of #AI to Assess Quality & Reporting’ session

Register at peerreviewcongress.org!

@jama.com @bmj.com

A brief guide to statistical analysis of grouped data in preclinical research Nature Metabolism - Clustering and nesting (C&N) arise in many preclinical studies, such as when animals are group-housed or share litters, or in cell culture. Ignoring C&N...

A brief guide to statistical analysis of grouped data in preclinical research rdcu.be/er3HG

ScienceGuardians X account @SciGuardians. Bio reads: "Empowering academia with tools, training and transparency 🌐 First fully verified journal club & post-publication peer review 🔎 scienceguardians.com | Nonprofit". Their header image reads "First fully verified journal club".

An excerpt from the ScienceGuardians website: At ScienceGuardians, we are committed to: – Creating a Secure Environment: Our stringent verification process ensures that every member is a legitimate contributor from the academic, research, or publishing realm. This commitment to authenticity sets the stage for meaningful and responsible discussions. While we provide the choice for members to stay anonymous in discussions, their identities have been verified, ensuring they are legitimate members of the community, not unverified individuals engaging in disruptive behavior. By hosting authors, reviewers, editors, academic institutions, and publishers, we ensure a balanced and comprehensive perspective in every dialogue.

Larry the cat's profile under the name Lawrence Richardson. The profile picture is a cat.

ScienceGuardians is a platform describing itself as the "first fully verified journal club" dedicated to fighting the "PubPeer Network Mob".

They boast of a stringent verification process.

On a whim, I registered an account for Larry Richardson, my grandma's cat.

It was approved in 2 hours.

Join us this summer at our meeting "Statistical Methods, Developments, and Challenges in Geroscience": training.publichealth.indiana.edu/campaign/ger... scholarships available to support attendance!

puppy scans 😂

CONSORT 2025 statement: updated guideline for reporting randomised trials Background Well designed and properly executed randomised trials are considered the most reliable evidence on the benefits of healthcare interventions. However, there is overwhelming evidence that the...

Happy CONSORT update day www.bmj.com/content/389/...