The Braun Lab

Biological Laboratory | LEGO® Ideas This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…

I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...

Bay Area Chromatin Club - In Person Symposium: March 5, 2026 The Chromatin Club Bay Area was founded to foster a scientific community between academic and industry members in and around the Bay Area.

Our full BACC lineup of speakers is up! Looks to be a fun program with talks from UCSC, Berkeley, Stanford, UCSF, and Genentech. Take a peek- still slots available to register and present a poster. March 5, 1-5pm

www.eventbrite.com/e/bay-area-c...

Night Science comes to Denmark this week! I'm giving a (day science) talk on cellular learning on Monday at the Danish Cancer Institute in Copenhagen (1pm). And then on Tuesday we do a full day Night Science workshop there!
www.cancer.dk/danish-cance...

Ancient co-option of LTR retrotransposons as yeast centromeres - Nature Evolutionarily related ‘proto-point’ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with re...

Our paper is now out in Nature:

“Ancient co-option of LTR retrotransposons as yeast centromeres”

www.nature.com/articles/s41...

A short thread on how retrotransposons helped give rise to yeast point centromeres.

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💫 We're hiring! The Computational Biology Facility is looking for a Computational Proteomics Scientist to collaborate on cutting-edge proteomics projects, develop new analytical approaches, and publish impactful research.
Apply by April 12 at: www.fmi.ch/education-ca...

Hey Chromatin Friends!
Long time no chromatin question...
For many of you, CUT&x (RUN/Tag) works really well but some of you have had their frustrations with CUT and "gone back" to ChIP-Seq. Can you share your experiences in the comments!?
Would love to hear from you!
Sharing is appreciated : )

Empowering biological knowledgebases: advances in human-in-the-loop AI-driven literature curation Abstract. Biological knowledgebases facilitate discovery across the life sciences by structuring experimental findings into human-readable and computable f

Empowering biological knowledgebases: advances in human-in-the-loop AI-driven literature curation url: academic.oup.com/bioinformati... @elixiruknode.org @biocurator.bsky.social

On Feb 4, the GfG workshop 'On the Path to a Professorship' brought early-career researchers to Berlin for practical advice on applications and insider tips for the next career step. Thanks to Ann Ehrenhofer-Murray, Sandra Hake, and Reinhard Köster for organizing! Next workshop planned for 2027/28.

Pombase gene page with an arrow pointing at the link to OpenCloning

🚀 Update from @pombase.bsky.social!

Gene pages now link to OpenCloning. Load the gene region instantly and design primers + cloning strategies in one click 🧬🧪✨

To get started with OpenCloning, check the docs: docs.opencloning.org

Please join Andreas Ladurner and me for the GRC Chromatin Structure and Function conference to be held near Barcelona Spain from May 31-June 5! We accepting abstracts for posters and talks. The meeting is preceded by an awesome GRS. Learn more in our video below and apply www.grc.org/chromatin-st...

I’ll be there 😃! Can’t wait, should be an outstanding conference!

STI1 domain engages transient helices to mediate Dsk2 phase separation and proteasome condensation - The EMBO Journal Ubiquitin-binding shuttle proteins are important components of stress-induced biomolecular condensates in cells. Yeast Dsk2 scaffolds proteasome-containing condensates via multivalent interactions wit...

Yeast ubiquilin Dsk2 scaffolds proteasome-containing condensates under stress via multivalent interactions – @castanedalab.bsky.social et al show how dynamic interactions among its STI1 domain & transient helices in its disordered region promote its phase-separation
link.springer.com/article/10.1...

New Preprint www.biorxiv.org/content/10.6... from our lab - work by (now) Dr. Feyza Polat Haas with fabulous contributions from many. We show that mammals have a 💪 POWER-Spliceoeome in the 🧠 optimized for metabolic functions. This happens because SNRPB (SmB) is replaced by its paralogue SNRPN (SmN).

Maßnahmen zur Karriereförderung von Wissenschaftlerinnen Vor dem Hintergrund der deutschlandweiten Unterrepräsentanz und von der weiterhin bestehenden strukturellen Benachteiligung von Wissenschaftlerinnen auf Leitungsebene können Karrierefördermaßnahmen de...

Zur Förderung der Frauen in der Wissenschaft bietet die DFG zusätzliche Karrieremaßnahmen an, die über die Chancengleichheitspauschale finanziert werden können. Ziel ist es, Sichtbarkeit zu erhöhen, Qualifikation zu stärken und weitere Karriereschritte zu unterstützen. #WomenInScience
sohub.io/ollu

Happy International Day of Women and Girls in Science! 🧪 Don't forget to send in your nominations for the FEBS | EMBO #WomenInScience Award.

Deadline: 15 May

Read more:
https://www.embo.org/the-embo-communities/febsembo-women-in-science-awardees/nominate-for-the-women-in-science-award/
#award

2nd postdoc job alert in the Crick Institute in London. Project will examine the role of motors & the cytoskeleton (actin, septins and microtubules) during vaccinia virus egress using biochemical, structural & cellular approaches + live cell imaging. spread the word.
crick.ac.uk/WayPostdoc20...

Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability Marmolejo et al. uncover transcription condensate dynamics at histone locus bodies across the cell cycle. These dynamics are governed by cell cycle (DDK and CDK1/2) and checkpoint (ATR-CHK1) kinases t...

Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability

www.cell.com/molecular-ce...

DOT1L provides transcriptional memory through PRC1.1 antagonism - Nature Cell Biology Neville, Ferguson et al. show that non-canonical Polycomb repressive complex 1.1-mediated gene silencing is antagonized by DOT1L and is required for the therapeutic efficacy of Menin and DOT1L inhibit...

H3K79me2/3 is sufficient to antagonise PRC1 www.nature.com/articles/s41...

Ad for a postdoc position in centromere biology with colorful chromosomes and centromeres made out of FIMO.

🧪 My lab has an opening for a postdoc position soon! Please share/get in touch!

Top: FK506-resistant strains isolated from the Mucor circinelloides complex. Phenotypic analysis of FK506-resistant isolates in Mucor janssenii CBS185.68 (PS1), Mucor bainieri CBS293.63 (PS3), and Mucor atramentarius CBS202.28 (PS6). WT, wild-type; M, mendelian mutant; E, epimutant. Bottom: Schematic overview of epigenetic silencing contributing to antifungal resistance in Mucor species. fkbA expression enables FKBP12 production and FK506 sensitivity (yeast-like morphology). Epigenetic silencing of fkbA via RNAi and/or heterochromatin leads to FK506 resistance and hyphal growth. Generated with BioRender.com.

#Antifungal resistance is a global threat, but epigenetic mechanisms drive rapid, reversible adaptation in fungi. This study shows that #RNAi or #heterochromatin driven #epimutations transiently silence the gene fkbA to confer FK506 #tacrolimus resistance in #Mucor @plosbiology.org 🧪 plos.io/4qdttWc

Antiviral reverse transcriptases reveal the evolutionary origin of telomerase Defense-associated reverse transcriptases (DRTs) employ diverse and distinctive mechanisms of cDNA synthesis to protect bacteria against viral infection. However, much of DRT family diversity remains ...

1/10 Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from?

Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria.
www.biorxiv.org/content/10.1...

Mitosis lovers, get ready for Dubrovnik! 🔬🎉
I’m super excited to be organizing the 4th Mitotic Spindle Conference with Nenad Pavin, and we can’t wait to see you there!
Want your abstract to be selected for a talk? Submit by Feb 8!
www.phy.pmf.unizg.hr/~mitosis/
#SpindleCroatia2026

Dont miss out on it ! Hands on Summer School.
Cut&Run, Cut@Tag, ChIP, ATACseq and analyse your own data ! ➡️Unique opportunity ! 14 exiting days ➕ Daily high profile lectures.
👉 Applications & info: bit.ly/4oGDR8f

While we’ll miss her greatly, we’re incredibly proud of all she has achieved—and truly happy to see her take the next step as a postdoc in Nils Krietenstein’s group 🇩🇰 as part of the new EpiC led by @groth-anja.bsky.social. Wishing you a fantastic start, Agnis, and all the best for what comes next! 🌱

Time to say goodbye 💙
This week we celebrated the farewell of @agnisrota.bsky.social, marking 6 yrs of impressive PhD work—from LMU Munich to JLU Giessen. With enthusiasm for science & contributions to many projects, Agnis left a lasting mark on our lab & collaboration with @al-sadylab.bsky.social.

PhD position in my lab!

Public consultation on this decision is now open. Please express your opinion. Anyone can write to the address provided here: www.bafu.admin.ch/fr/newnsb/Te...

The Federal Council is proposing the dissolution of the Swiss Science Council.

Independent fact-based, scientific advice should be available for policy decisions.

Very excited about this new preprint, in which @juliacoronasserna.bsky.social shows how cells ensure that fusion with another cell is irreversible!

www.biorxiv.org/content/10.6...

@biology-unige.bsky.social

👇

This was a joint effort between yeast and mammalian experts
@kilchertlab.bsky.social @bulutkarslioglu.bsky.social
@angela-taddei.bsky.social, D. Włoch-Salamon and co-workers, with great support from additional NuQuest members and @Biomol_MDPI. 4/n
@pombase.bsky.social @yeastgenome.bsky.social