Kevin Messacar MD PhD

Permethrin-Treated Baby Wraps for the Prevention of Malaria | NEJM Malaria remains a major cause of childhood death in sub-Saharan Africa. We leveraged the traditional practice of mothers carrying children on their backs in cloth wraps to assess whether treating t...

Ever since I learned about this study enrolling I have been eagerly awaiting the results. Researchers in Uganda took a centuries-old cultural practice mothers carrying babies on their backs in cloth wraps and turned it into a public health tool. You got to love it!
www.nejm.org/doi/full/10....

Early registration ends October 1 for our Pediatric Infectious Disease Fall Update
🗓️Wed November 5 in person & online
✏️MOC & CME
🦠Updates on vaccines, measles, COVID, influenza, sinusitis, pneumonia and skin & soft tissue infections
ce.childrenscolorado.org/content/27th...
@cupediatrics.bsky.social

Join our 1-day Infectious Diseases Conference!
When: Nov 5
Where: Virtual or in-person at Children's Hospital Colorado
What: Updates on ACIP, vaccines & vaccine hesitancy; mgmt of measles, UTI, SSTI, CAP, sinusitis, tick illnesses, and more!
Register now: ce.childrenscolorado.org/content/26th...

Clinical Pathway Revision Increases Amoxicillin Monotherapy and 5-Day Durations of Therapy for Pediatric Community-Acquired Pneumonia in the Emergency Department and Urgent Care: A Quality Improvement... The American Academy of Pediatrics recommends 5-day amoxicillin monotherapy as first-line treatment for pediatric uncomplicated community-acquired pne…

Treat pediatric CAP with 5 days of amox monotherapy. Check out our QI project here in @annalsofem.bsky.social using pre-clicked durations in order sets and an EHR-integrated pathway! #Pedsky #PedsIDSky #AntimicrobialStewardship #EM #PEM #EmergencyMedicine

www.sciencedirect.com/science/arti...

Dr. Kevin Messacar stands in front of a blue backdrop.

Why did viruses like flu and RSV reemerge after the #COVID19 pandemic? A recent study from our #InfectiousDisease experts led by principal investigator @kmess44.bsky.social reveals insights about viruses, our immune system and how to prepare for the future: prn.to/4lztth8

Now is the time to integrate serology into routine infectious disease surveillance Syndromic and virological surveillance are essential for epidemic intelligence, which can be defined as the capacity to effectively identify, monitor, understand, and forecast infectious disease outbr...

New comment

Now is the time to integrate serology into routine infectious disease surveillance

www.thelancet.com/journals/lan...

Thanks Jess! I have no idea what I am doing on here... even less so than Twitter. I'd love to follow more #IDSky so please follow/reach out if you are interested in #pedsID #diagnosticstewardship #enterovirus #EVD68 #EVA71 #acuteflaccidmyelitis #encephalitis #meningitis #pandemicpreparedness

Thanks Jess! I have no idea what I am doing on here... even less so than Twitter. I'd love to follow more #IDSky so please follow/reach out if you are interested in #pedsID #diagnosticstewardship #enterovirus #EVD68 #EVA71 #acuteflaccidmyelitis #encephalitis #meningitis #pandemicpreparedness

Dynamics of endemic virus re-emergence in children in the USA following the COVID-19 pandemic (2022–23): a prospective, multicentre, longitudinal, immunoepidemiological surveillance study In this study, we captured immunological evidence of endemic virus re-emergence in children following lifting of pandemic NPIs, which revealed high rates of exposure to endemic respiratory pathogens i...

This study confirms what we all saw - a surge in endemic respiratory viruses after COVID precautions lifted, and demonstrates the utility of immunoepidemiological surveillance…

#IDSky

www.thelancet.com/journals/lan...

Authors noted:
🟢 ⬆️Ab titres supports the hypothesis of ⬆️susceptible population of young children building up during the pandemic infection pause
🟢 subsequent ⬆️Ab in population-level immunity after
NPIs lifted
🟢⬆️Ab likely reflects ⬆️viral circulation after NPIs lifted➡️virus re-emergence

Dynamics of endemic virus re-emergence in children in the USA following the COVID-19 pandemic (2022–23): a prospective, multicentre, longitudinal, immunoepidemiological surveillance study.
h/t to @cidrap.bsky.social www.thelancet.com/journals/lan...

Dynamics of endemic virus re-emergence in children in the USA following the COVID-19 pandemic (2022–23): a prospective, multicentre, longitudinal, immunoepidemiological surveillance study In this study, we captured immunological evidence of endemic virus re-emergence in children following lifting of pandemic NPIs, which revealed high rates of exposure to endemic respiratory pathogens in a large group of seronegative, predominantly younger, children. This study demonstrates the feasibility and utility of immunoepidemiological surveillance to enable more precise and accurate modelling of pathogen circulation dynamics to predict and prepare for future waves of disease.

Dynamics of endemic virus re-emergence in children in the USA following the COVID-19 pandemic (2022–23): a prospective, multicentre, longitudinal, immunoepidemiological surveillance study

Yes the infection pause or immune gap is measurable.

www.thelancet.com/jo...
1/10

Immunologic study shows rebound of other viruses after COVID measures lifted

The authors showed how a relatively small serosurveillance scheme could complement traditional surveillance, enhancing epidemic understanding and forecast modeling.

www.cidrap.umn.edu/c...

Dynamics of endemic virus re-emergence in children in the USA following the COVID-19 pandemic (2022–23): a prospective, multicentre, longitudinal, immunoepidemiological surveillance study In this study, we captured immunological evidence of endemic virus re-emergence in children following lifting of pandemic NPIs, which revealed high rates of exposure to endemic respiratory pathogens i...

New Research:

Dynamics of endemic virus re-emergence in children in the USA following the COVID-19 pandemic (2022–23): a prospective, multicentre, longitudinal, immunoepidemiological surveillance study

www.thelancet.com/journals/lan...