Silvia Remeseiro Lab

Join the PALS Summer School in Transcriptomics🧬 🇸🇪
www.trippus.net/summerschool...
and learn data integration
-Single-cell multiome
-ATAC-seq+3Dgenomics
-Non-coding variants+Transcription Factors
-Large-scale epigenomics
-Spatial
@scilifelab.se
@kawresearch.bsky.social
@remeseiro-lab.bsky.social

The PALS Summer School in Omics is back!
Register now for the 2026 edition! 👇

Registration for the PALS Summer School in Transcriptomics is Open 🧬 23-26 June 2026 www.trippus.net/summerschool...
Join us in this wonderful place 🇸🇪 to learn
Theory & Computation from Famous Scientists in the Field
w @remeseiro-lab.bsky.social
Support by @scilifelab.se & @kawresearch.bsky.social

Christina Stankey: not on Bluesky (I still think)
@evgenykvon.bsky.social
@remeseiro-lab.bsky.social
@sj-marzi.bsky.social
@mosterwalder.bsky.social
@akispapantonis.bsky.social
@radaiglesiaslab.bsky.social
@andersshansen.bsky.social
@mariekeoudelaar.bsky.social

🗓️ 23-26 June 2026 🇸🇪
#PALS #summerschool in #OMICS is back!
Soon registration and info about speakers for the 3rd edition!

Organized by @claudiocantu81.bsky.social and me, @remeseiro-lab.bsky.social, with the support from @scilifelab.se and @kawresearch.bsky.social

Project Assistant The Department of Medical and Translational Biology at the Faculty of Medicine is now seeking a project assistant for a research project related to human brain aging. The position is full-time and lim

📣We are looking for a Project Assistant to join my group at the Wallenberg Center for Molecular Medicine at Umeå University. Join us if you are interested in transposable elements, epigenetics and human brain aging. 🧠🧬 Dont hesitate to reach out with any questions! 📣
umu.varbi.com/en/what:job/...

Thanks a lot 😊

Postdoctoral Researcher in "Cancer Neuroscience: the impact of neural activity on 3D genome organization and cellular plasticity in glioblastoma”

Excited to share I’ve received a #SSMF #Consolidator grant!

📣 Recruiting a #postdoc to study #cancer #neuroscience #3Dgenomics #multiomics #singlecellomics

🔬How neural inputs shape #3Dgenome and #cellplasticity in #glioblastoma #GBM

Interested? Apply now 👇
rb.gy/m7xz7b

🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉
Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨

#PhD #3DGenome

Thanks ☺️

Thanks ☺️

Apply and join my lab at @umeauniversitet.bsky.social 🇸🇪 and #WCMM, generously funded by #SSMF #Consolidator @vetenskapsradet.bsky.social #Cancerfonden @kawresearch.bsky.social

Postdoctoral Researcher in "Cancer Neuroscience: the impact of neural activity on 3D genome organization and cellular plasticity in glioblastoma”

Excited to share I’ve received a #SSMF #Consolidator grant!

📣 Recruiting a #postdoc to study #cancer #neuroscience #3Dgenomics #multiomics #singlecellomics

🔬How neural inputs shape #3Dgenome and #cellplasticity in #glioblastoma #GBM

Interested? Apply now 👇
rb.gy/m7xz7b

#CancerNeuroscience EACR conference there we go!

Thanks to all speakers, including bsky users @winklerlab.bsky.social @claudiakleinman.bsky.social @nelander-lab.bsky.social @gocastelobranco.bsky.social, the Ragnar Söderberg foundation, and co-hosts @remeseiro-lab.bsky.social, @maawim.bsky.social, and Fredrik Swartling.

Emmanuelle Charpentier has been appointed honorary citizen of Umeå Municipality, and in connection with the honorary citizenship ceremony, the Nobel Prize winner is making a long-awaited visit to her alma mater for a public seminar/talk. Read more here: www.umu.se/en/events/se...

MLL2 facilitates long-range gene regulation through LINE1 elements Transcriptional regulation is tightly linked to chromatin organization, with H3K4me3 commonly marking both active and bivalent promoters. In embryonic stem cells (ESC), MLL2 is essential for H3K4me3 d...

#Preprint alert! 📣

We are thrilled to share the work led by Lara Zorro-Shahidian and Lucio di Filippo, in which we show that #MLL2 controls gene expression in both #ESC and upon #differentiation by facilitating the #enhancer like activity of #LINE1 elements

www.biorxiv.org/cgi/content/...

What Epigenetics Teaches Us About Neuron–Glioma Interactions Neuron–glioma interactions through the epigenetic lens. Rewiring of epigenetic mechanisms, including alterations in the enhancer landscape and 3D chromatin organization, allows glioma cells to sense ....

Read here our 'Ideas & Speculations' now out @wiley.com #BioEssays on how #neuron–glioma #interactions begin to be
decoded through the #epigenetic lens.
#GBM #glioma #CancerNeuroscience

onlinelibrary.wiley.com/doi/10.1002/...

What Epigenetics Teaches Us About Neuron–Glioma Interactions Neuron–glioma interactions through the epigenetic lens. Rewiring of epigenetic mechanisms, including alterations in the enhancer landscape and 3D chromatin organization, allows glioma cells to sense ....

Read here our 'Ideas & Speculations' now out @wiley.com #BioEssays on how #neuron–glioma #interactions begin to be
decoded through the #epigenetic lens.
#GBM #glioma #CancerNeuroscience

onlinelibrary.wiley.com/doi/10.1002/...

Now out @genomeresearch.bsky.social this fantastic work in collaboration with Claudio Cantù's lab.

About how #Wnt signalling activation induces #CTCF binding and formation of new #chromatin #loops at #CREs of target genes.

genome.cshlp.org/content/earl...

Stronger Berzelius ready for the research of the future The latest upgrading of the supercomputer Berzelius at LiU has now been completed. Its doubled capacity enables researchers across Sweden to tackle current and future challenges in areas such as mater...

The latest upgrading of the #supercomputer Berzelius @liu.se has now been completed. Its doubled capacity enables researchers across Sweden to tackle current and future challenges in areas such as materials science, bioinformatics and machine learning #research #science
tinyurl.com/ydduwzc7

Starkare Berzelius är redo för framtidens forskning Nu är den senaste uppgraderingen av superdatorn Berzelius vid LiU klar. Med en fördubblad kapacitet kan forskare i hela Sverige ta sig an samtidens och framtidens utmaningar inom bland annat materialv...

Nu är den senaste uppgraderingen av superdatorn Berzelius @liu.se klar. Med en fördubblad kapacitet kan forskare i hela Sverige ta sig an samtidens och framtidens utmaningar inom bland annat materialvetenskap, bioinformatik och maskininlärning #forskning #vetenskap
tinyurl.com/nns7pks6

Welcome! You are invited to join a webinar: The 3D Regulatory Genome: Gaining mechanistic insights into long-range gene regulation through synthetic biology approaches. After registering, you will rec... Join our guest speaker, Dr. Alvaro Rada-Iglesias, in this exciting seminar on the 3D Regulatory Genome, sponsored by Enhanced Genomics.

Really looking forward to @radaiglesiaslab.bsky.social's talk on "Gaining mechanistic insights into long-range gene regulation through synthetic biology approaches" in @enhancedgenomics.bsky.social's seminar series.

📅 June 5th 2025 tomorrow
⏰ 4pm GMT

Please join us:
us02web.zoom.us/webinar/regi...

High-grade gliomas integrate into neural circuits in the human brain affecting cognition, language and decreasing survival. Fascinating field!
See you at #PALS2025

Are you a US-based researcher who want to return to #Sweden 🇸🇪 to establish your #research here?

This is your shot to make it happen 👇
strategiska.se/en/press-rel...

Conservation of regulatory elements with highly diverged sequences across large evolutionary distances Nature Genetics - Combining functional genomic data from mouse and chicken with a synteny-based strategy identifies positionally conserved cis-regulatory elements in the absence of direct sequence...

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...

Work funded by @kawresearch.bsky.social @vetenskapsradet.bsky.social #Cancerfonden #StratNeuro #Kempestiftelsen #CancerforskningsfondenNorrland

📍 @umeauniversitet.bsky.social #WCMM_Umeå

Collab with #CemalErdem @kirkebylab.bsky.social @hornblad-lab.bsky.social

With these studies we have showed that #epigenetic regulators of the #neuron-to-glioma axis can serve as actionable #targets in #GB.

Viewing neuron-glioma interactions through an epigenetic lens helped us understand how glioma cells exploit neural signals to fuel their growth.

#ARX, #GSX2 and members of the #DLX family were identified as key #TFs regulating #GABAergic related networks in #GB.

AMPAR antagonist NBQX reduces GB cell proliferation in co-culture with glutamatergic neurons, as expected. But the GABAAR antagonist picrotoxin doesn’t affect GB growth in the setting with GABAergic interneurons. This suggests #GABA signalling drives #GB growth through non-synaptic mechanisms.