Lisa Heinke

Induction of menstruation in mice reveals the regulation of menstrual shedding During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵

The mechanistic basis of cargo selection during Golgi maturation Resident proteins of the Golgi recycle in vesicles and the protein GOLPH3 enables the COPI vesicle coat to accomplish this.

The mechanistic basis of cargo selection during Golgi maturation. From Rebecca Taylor, @katciazynska.bsky.social, @jggkaufman.bsky.social & @grigorytagiltsev.bsky.social at @mpibiochem.bsky.social with David Owen and Sean Munro's group @cellbiol-mrclmb.bsky.social | www.science.org/doi/10.1126/...

Many thanks to Sean (@cellbiol-mrclmb.bsky.social) for writing this Journal Club for us!

🎉 Just 1 week to go until #ECDO2025 in Berlin!

This will be an exciting meeting featuring a fantastic lineup of speakers.

🧬 This year, we’ll dive deep into the crosstalk between different types of cell death in health and disease.

📍 We can’t wait to welcome you! 7-10 Oct!!!

Check out this new Roadmap, a fantastic team effort by a consortium of ER researchers. Glad we could provide the space for this synthesis, which came out of discussions at a fruitful meeting, see below:

Cool article alert! Check out our futuristic Viewpoint below 🔮

And big thank you again to our fortune tellers, linked in the thread below 🥳

Are you excited?? Because I am!

25 years ago I was 10 and had just started secondary school yet our journal was already covering groundbreaking science, long before I'd even heard of molecular cell biology 🧐
Safe to say I'm fairly familiar with it now 🤭

Enjoy our issue!!!!!!!!!!!

Great to see this out, it's always nice to see the work of early-career researchers featured! Thanks for putting me in touch with Chems and Emma :)

Big Thanks @lisaheinke.bsky.social and Nature Reviews Molecular Cell Biology @natrevmcb.nature.com for the opportunity for our students, Chems and Emma, to write a Tools of the Trade piece on our recently published ControLD technique.

Looking forward to this conference on my home turf in a couple of months!

That's acceptable (unless the verb is "unleashing", which is not acceptable) 🤭

A good rule of thumb when it comes to deciding a title for your Review/Research article is the Harry Potter test as I like to call it.

Does your title fit into the scheme of "Harry Potter and..."? Then you know it's not a good scientific title.

Remodelling autoactive NLRs for broad-spectrum immunity in plants - Nature Cleavage by pathogen-derived proteases of an engineered chimeric protein activates its plant immune receptor component, enabling broad-spectrum resistance to pathogens in plants.

Plant NLR receptors mediate pathogen resistance, and so their engineering could lead to crops with broader pathogen specificity and so broader disease resistance. @nature, authors report one such attempt achieving resistance to several potyviruses. www.nature.com/articles/s41...

& shorturl.at/932j7

As an editor I have blasted primer sequences in the past in an attempt to confirm my paper mill suspicions… it’s a shame this is necessary at all but editors and scientists alike are grateful for referees that take the time! 🙏

Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease - Nature Reviews Molecular Cell Biology Transposable elements (TEs) comprise nearly half of the human genome. This Review discusses transcriptional and post-transcriptional mechanisms that repress TE activity, how TEs escape this suppressio...

We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease.
www.nature.com/articles/s41...

Precisely.

Which is why if a funder wants to require a version to be made open, it should be the preprint, as it is the only version that is *directly* and solely the work of the fundee.

ck.journalology.com/posts/journa...

My pleasure completely, great study and beautiful wing disc images 😊

JSPS Research Fellowship The Japan Society for the Promotion of Science (JSPS) Research Fellowship supports you as a highly qualified postdoc from Germany in conducting your research in Japan – regardless of discipline.

Hey my fellow Germans! I wasn't aware, but there is an AvH-JSPP postdoc fellowship, dedicated to German citizens aiming to do their postdoc in Japan. It covers salary + travel to Japan + startup for your life in Japan. Let me know if you are interested!
www.humboldt-foundation.de/en/apply/spo...

Associate or Senior Editor Nature Metabolism Job Title: Associate or Senior Editor Nature Metabolism Location: New York, Beijing or Shanghai Application Deadline: June 10th, 2025 About Springer Nature Group Springer Nature opens the doors to dis...

a great opportunity to join Nature Metabolism as an Associate or Senior editor
springernature.wd3.myworkdayjobs.com/SpringerNatu...

We were thrilled to welcome Dr. Lisa Heinke @lisaheinke.bsky.social, a Senior Editor at Nature Reviews Molecular Cell Biology, to Fudan University! She gave a fantastic talk on the editorial process and career paths as a scientific editor! Thank you, Lisa!

Our meeting at beautiful Dushu Lake near Suzhou ended yesterday after many great talks. I really enjoyed learning about cell death and immunity pathways associated with it!

Now I’m on my way to Fudan University for a lab visit and seminar, kindly hosted by @ichikawa-lab.bsky.social 🙌🏻

Mechanistic insights into gasdermin-mediated pyroptosis - Nature Reviews Molecular Cell Biology Activation of gasdermins (GSDMs) in response to infection or cell damage triggers membrane pore formation, leading to pyroptotic cell death. This Review discusses recent molecular and structural insig...

Xing has recently summarised recent insights on gasdermin pore formation for us @natrevmcb.nature.com, check out his article here: www.nature.com/articles/s41...

Traditional lunch venue

In front of the Shanghai Institute for immunity and infection with Xing Liu

Yesterday was my first day in Shanghai and I was lucky to enjoy a great visit to the Shanghai Institute of Immunity and Infection (by Chinese Academy of Science). Thank you to Xing Liu for being a wonderful host and ensuring a smooth trip for me 🙌🏻

We're hiring 📢

The Research Cross-Journal Editorial Team @natureportfolio.nature.com has not one, but TWO openings for Associate or Senior Editors in Life Sciences.

If you fancy a career in editorial, we'd love to hear from you 😀

Yes, that is me, for those who did not yet know. This was not planned but I am very happy to go 'home' even though I will miss a lot about Portugal. If you still want to visit, hurry, otherwise see you in Cambridge. If you want to know more contact me directly.
www.pdn.cam.ac.uk/news/dr-care...

Toxic friendships be like

“let’s run 25km on Sunday”

- “ok”

(My longest run ever and my first partial trail run!)

Anyone going to the #CSHLAsia meeting on Cell Death and Innate Imunity in Suzhou in May?

Because I am and I'd love to touch base! Give me a shout if you'll be there ☕

Outstanding review of insulin resistance with an eye towards insulin sensitization as a future goal
www.nature.com/articles/s41...

I wish I had no idea 🥺

You have my full sympathy. We just migrated and it wasn’t fun. Thoughts and prayers to you…