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Anna Leder

@annaleder.bsky.social

PhD student in Hiller lab, University of Basel | studying molecular chaperones and protein folding homeostasis

136 Followers  |  43 Following  |  8 Posts  |  Joined: 20.12.2023
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Posts by Anna Leder (@annaleder.bsky.social)

Thanks Elif!

13.08.2025 13:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you very much @nicolasluxfawzi.bsky.social!

12.08.2025 19:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you Elias!

11.08.2025 16:57 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks Ben!

11.08.2025 15:29 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Great teamwork with @masgu.bsky.social and I am very thankful for the huge support by Sebastian @hillerlab.bsky.social and Anne @spanglab.bsky.social!

11.08.2025 15:07 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

PDIA6 forms the scaffold of these phase separated condensates and we resolve the underlying calcium-dependent mechanism. Further chaperones - including Hsp70, Hsp40 and Hsp90 - are recruited into the condensates, where they enhance client proteins folding, functioning as β€œfolding factories”.

11.08.2025 15:07 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Happy to share my first publication, where we present our discovery of multi-chaperone condensates that orchestrate protein folding in the endoplasmic reticulum!
www.nature.com/articles/s41...

11.08.2025 15:07 β€” πŸ‘ 64    πŸ” 18    πŸ’¬ 5    πŸ“Œ 2

Check out this amazing work on the functional cycle of Hsp70 BiP NBD at atomic resolution by @masgu.bsky.social

02.06.2025 14:38 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0