Single-cell multiomic approaches define a gradual, spatially-regulated epigenetic and transcriptional transition from embryonic to adult neural stem cells #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.06.704429v1
@prepub-singlecell.bsky.social
feeds: biorxiv, medrxiv, arxiv.q-bio, arxiv.cs, arxiv.math, Research Square regex: '(single(- )(cell|nuclei)|s[cn]RNA-seq)' If you have suggestions, please get in contact with @willmacnair :)
Single-cell multiomic approaches define a gradual, spatially-regulated epigenetic and transcriptional transition from embryonic to adult neural stem cells #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.06.704429v1
An AI/ML-Powered Workflow for End-to-End Cell Line Development #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.04.703387v1
A knock-in Six2Cre line reveals transient interstitial potential in nephron progenitors #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.04.703893v1
A Multi-Organ Single-Cell Atlas Maps Allergen and Organ-Specific Cellular Dynamics in the Progression from Food Allergy to Anaphylactic Shock #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.04.703914v1
TLR5 drives metabolic dysfunction-associated steatohepatitis through lipid- and flagellin-induced hepatocyte injury signalling #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.05.703969v1
Integrative Single-Cell Epigenomic Atlas Annotates the Regulatory Genome of the Adult Mouse Brain #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.07.704075v1
Every Cell Counts: Tomato Root Responses to Nitrogen at Single-Cell Resolution #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.06.704465v1
Decomposing multi-scale dynamic regulation from single-cell multiomics with scMagnify #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.03.703669v1
Identification and Characterization of Metastasis-initiating cells #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.03.703643v1
Unravelling genome-wide mosaic microsatellite mutations at single-cell resolution #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.04.703915v1
Mouse macrophages from diverse niches show generally divergent age-related transcriptional remodeling signatures #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.03.703654v1
Mapping trans-eQTLs at single-cell resolution using Latent Interaction Variational Inference. #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.04.703363v1
Single-cell machine learning uncovers genetically anchored, cell-type specific programs of Alzheimer's disease #SingleCell π§ͺπ§¬π₯οΈ
https://www.medrxiv.org/content/10.64898/2026.01.31.26345282v1
Multiscale RNA editing analysis reveals cell type specific regulatory programs across disease states in acute myeloid leukemia #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.04.703797v1
PhyloSOLID: Robust phylogeny reconstruction from single-cell data despite inherent error and sparsity #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.04.703905v1
ProtoCloud: a Prototypical Self-explaining Model for Single-cell Analysis #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.06.704364v1
A modular transcript enrichment strategy for scalable, atlas-aligned, and clonotype-resolved single-cell transcriptomics #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.06.703342v1
Learning to Discover at Test Time #SingleCell π§ͺπ§¬π₯οΈ
https://arxiv.org/abs/2601.16175
CellForge: Agentic Design of Virtual Cell Models #SingleCell π§ͺπ§¬π₯οΈ
https://arxiv.org/abs/2508.02276
Somatic Mechanotherapy Activates a Spatiotemporally Synchronized CPTC Wnt Axis for Gut Regeneration #SingleCell π§ͺπ§¬π₯οΈ
https://arxiv.org/abs/2602.05451
Beyond Independent Genes: Learning Module-Inductive Representations for Gene Perturbation Prediction #SingleCell π§ͺπ§¬π₯οΈ
https://arxiv.org/abs/2602.04901
Monitoring intracellular antibiotic concentrations in real-time using allosteric biosensors #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.05.704027v1
Scalable probe-based single-cell transcriptional profiling for virtual cell perturbation mapping and synthetic biology phenotyping #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.04.703058v1
Whole-body single-cell atlas of an adult vertebrate in homeostasis and regeneration #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.03.703562v1
Activated Human Pancreatic Stellate Cells Signature Communication in Type 1 Diabetes #SingleCell π§ͺπ§¬π₯οΈ
https://www.researchsquare.com/article/rs-8704281/latest
Opioid-induced transcriptional reprogramming of cerebrospinal fluid immune cells drives neuroinflammation in SIV-infected rhesus macaques #SingleCell π§ͺπ§¬π₯οΈ
https://www.researchsquare.com/article/rs-8632387/latest
Overmaturation as a major trajectory of naive CD4 T cell aging #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.02.703431v1
TREM2 agonist antibody rebuilds the resident synovial macrophage lining barrier in rheumatoid arthritis #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.02.02.703430v1
Reduced Complex III assembly dampens host inflammation as an adaptive response to viral infection #SingleCell π§ͺπ§¬π₯οΈ
https://www.biorxiv.org/content/10.64898/2026.01.30.702752v1
OmniCellTOSG: The First Cell Text-Omic Signaling Graphs Dataset for Graph Language Foundation Modeling #SingleCell π§ͺπ§¬π₯οΈ
https://arxiv.org/abs/2504.02148