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@prepub-singlecell.bsky.social

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Latest posts by prepub-singlecell.bsky.social on Bluesky

Single-cell multiomic approaches define a gradual, spatially-regulated epigenetic and transcriptional transition from embryonic to adult neural stem cells #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.06.704429v1

08.02.2026 17:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

An AI/ML-Powered Workflow for End-to-End Cell Line Development #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.04.703387v1

08.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

A knock-in Six2Cre line reveals transient interstitial potential in nephron progenitors #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.04.703893v1

08.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

A Multi-Organ Single-Cell Atlas Maps Allergen and Organ-Specific Cellular Dynamics in the Progression from Food Allergy to Anaphylactic Shock #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.04.703914v1

08.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

TLR5 drives metabolic dysfunction-associated steatohepatitis through lipid- and flagellin-induced hepatocyte injury signalling #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.05.703969v1

08.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Integrative Single-Cell Epigenomic Atlas Annotates the Regulatory Genome of the Adult Mouse Brain #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.07.704075v1

08.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Every Cell Counts: Tomato Root Responses to Nitrogen at Single-Cell Resolution #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.06.704465v1

07.02.2026 17:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Decomposing multi-scale dynamic regulation from single-cell multiomics with scMagnify #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.03.703669v1

07.02.2026 08:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Identification and Characterization of Metastasis-initiating cells #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.03.703643v1

07.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Unravelling genome-wide mosaic microsatellite mutations at single-cell resolution #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.04.703915v1

07.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Mouse macrophages from diverse niches show generally divergent age-related transcriptional remodeling signatures #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.03.703654v1

07.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Mapping trans-eQTLs at single-cell resolution using Latent Interaction Variational Inference. #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.04.703363v1

07.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Single-cell machine learning uncovers genetically anchored, cell-type specific programs of Alzheimer's disease #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.medrxiv.org/content/10.64898/2026.01.31.26345282v1

07.02.2026 08:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Multiscale RNA editing analysis reveals cell type specific regulatory programs across disease states in acute myeloid leukemia #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.04.703797v1

07.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

PhyloSOLID: Robust phylogeny reconstruction from single-cell data despite inherent error and sparsity #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.04.703905v1

07.02.2026 08:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

ProtoCloud: a Prototypical Self-explaining Model for Single-cell Analysis #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.06.704364v1

07.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

A modular transcript enrichment strategy for scalable, atlas-aligned, and clonotype-resolved single-cell transcriptomics #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.06.703342v1

07.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Learning to Discover at Test Time #SingleCell πŸ§ͺ🧬πŸ–₯️
https://arxiv.org/abs/2601.16175

06.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

CellForge: Agentic Design of Virtual Cell Models #SingleCell πŸ§ͺ🧬πŸ–₯️
https://arxiv.org/abs/2508.02276

06.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Somatic Mechanotherapy Activates a Spatiotemporally Synchronized CPTC Wnt Axis for Gut Regeneration #SingleCell πŸ§ͺ🧬πŸ–₯️
https://arxiv.org/abs/2602.05451

06.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Beyond Independent Genes: Learning Module-Inductive Representations for Gene Perturbation Prediction #SingleCell πŸ§ͺ🧬πŸ–₯️
https://arxiv.org/abs/2602.04901

06.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Monitoring intracellular antibiotic concentrations in real-time using allosteric biosensors #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.05.704027v1

06.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Scalable probe-based single-cell transcriptional profiling for virtual cell perturbation mapping and synthetic biology phenotyping #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.04.703058v1

06.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Whole-body single-cell atlas of an adult vertebrate in homeostasis and regeneration #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.03.703562v1

06.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Activated Human Pancreatic Stellate Cells Signature Communication in Type 1 Diabetes #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.researchsquare.com/article/rs-8704281/latest

05.02.2026 17:06 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Opioid-induced transcriptional reprogramming of cerebrospinal fluid immune cells drives neuroinflammation in SIV-infected rhesus macaques #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.researchsquare.com/article/rs-8632387/latest

05.02.2026 17:06 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Overmaturation as a major trajectory of naive CD4 T cell aging #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.02.703431v1

05.02.2026 17:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

TREM2 agonist antibody rebuilds the resident synovial macrophage lining barrier in rheumatoid arthritis #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.02.02.703430v1

05.02.2026 17:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Reduced Complex III assembly dampens host inflammation as an adaptive response to viral infection #SingleCell πŸ§ͺ🧬πŸ–₯️
https://www.biorxiv.org/content/10.64898/2026.01.30.702752v1

05.02.2026 17:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

OmniCellTOSG: The First Cell Text-Omic Signaling Graphs Dataset for Graph Language Foundation Modeling #SingleCell πŸ§ͺ🧬πŸ–₯️
https://arxiv.org/abs/2504.02148

05.02.2026 08:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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