Haoran Cai

GitHub - lowrylab/WGCNA_agent Contribute to lowrylab/WGCNA_agent development by creating an account on GitHub.

Weighted Gene Co-expression Network Analysis (WGCNA) has been the go to program for analysis of gene expression modules for nearly two decades but it is a difficult to implement. To make it easier to use WGCNA, I used Codex to build a human in the loop agentic workflow. github.com/lowrylab/WGC...

Methods for knowledge-based biodiversity monitoring and management under uncertainty (BioM) - UiO:Life Science BioM develops new interdisciplinary methods to model and govern biodiversity under uncertainty, combining ecology, statistics, and philosophy. The project delivers predictive tools, normative framewor...

2 PhD & 1 postdoc available at BioM in Oslo
www.uio.no/english/rese... Interdisciplinary methods to model and govern biodiversity under uncertainty. Re-post widely! Work with statistical ecologists Olav Skarpaas (Natural History Museum Oslo @uio.no) @t-ergon.bsky.social

Promises to be poppin (🍿)

BUT SRSLY PLEASE REGISTER, WE ARE SO EXCITED!!!!!!!!!!!!

A pleiotropic hitchhiking model recapitulates alignments between fly wing divergence and variation https://www.biorxiv.org/content/10.64898/2026.02.19.706930v1

Don't miss this issue's Editor's Choice article: "Gene network topology drives the mutational landscape of gene expression" by Sylvain Pouzet & Arnaud Le Rouzic. Free to read here: doi.org/10.1093/evol...

In #GENETICS, a new model developed by @christianlandry.bsky.social and colleagues examines how molecular dominance determines total protein activity and contributes to phenotypic dominance. buff.ly/CfaTDp7

PhD Research Fellows in geosciences, planetary or exoplanetary sciences – up to three positions (294610) | University of Oslo Job title: PhD Research Fellows in geosciences, planetary or exoplanetary sciences – up to three positions (294610), Employer: University of Oslo, Deadline: Sunday, March 1, 2026

Apply for PhD Fellowships at the Centre for Planetary Habitability in Oslo! There are projects for geologists, paleontologists, paleobiologists, astrobiologists, stats-y folks, geoscientists and planetary folks! www.jobbnorge.no/en/available...

Our paper is out in MBE! doi.org/10.1093/molb...

We tracked TF binding site evolution across 589 grass species, and found that while binding preferences are pretty stable over 80 million years of evolution, individual binding sites have turned over a lot.

Thread here: bsky.app/profile/char...

Davis Summer Population Genomics Program Want to learn population genetics? Please fill out this form to indicate your potential interest in a 2-week intensive online summer population genetics course taught by Jeffrey Ross-Ibarra and Graham...

Fun news! @gcbias.bsky.social and I are teaching a 2-week online population genetics workshop this summer to raise money for the Center for Population Biology at UC Davis. We're trying to gauge interest -- please fill this out if you might be interested! And please share broadly!

MBE | Highlight: Dark skin and cancer suppression in humans—an evolutionary spandrel?

The recent MBE Review on the evolution of dark skin in humans is the focus of January's Highlight.

Highlight: Dark skin and cancer suppression in humans—an evolutionary spandrel?
🔗 doi.org/10.1093/molbev/msag012

#evobio #molbio

Chromatin state architecture governs transcription factor accessibility across plant genomes Author summary In eukaryotes, DNA is tightly associated with histone proteins. Histone covalent modifications and histones isoforms, also called histone variants provide most of the complexity of chro...

This is a very special paper for me. I had the idea of combining transcription factor binding with chromatin in 2016/8. It took some time, but thanks to Fred and Vikas, we can finally share the story in @plos.org Genetics looking at chromatin states in Arabidopsis and Marchantia. #PlantScience

Homepage - 2026 Population, Evolutionary, and Quantitative Genetics Conference Visit our website to learn more.

PEQG! My favorite conference ever*. Single session, fantastic talks, great discussions. Only once every 2 years. And in the best conference location too! Abstract deadline coming up Feb 5!

*Disclosure: I am required to say it's the best conference because it is and I told my mom I wouldn't lie.

Assessing the Impact of Whole Genome Duplication on Gene Expression and Regulation During Arachnid Development Abstract. Whole genome duplication (WGD) generates a new genetic material that can contribute to the evolution of developmental processes and phenotypic di

A genome-wide comparison of #gene regulatory sequences & embryonic gene expression in arachnids - new insights into the impact of the arachnopulmonate whole #genome duplication academic.oup.com/gbe/article/... #biodiversity #genomics

How do bacteria deal with double costs? And how costly are unusual levels of mistranslation anyway? In short - antibiotics are more of an issue than less/more mistranslation, but the latter changes how populations deal with antibiotics. For the long story, check out our new paper!

Research Associate-Fixed Term - East Lansing, Michigan, United States Position Summary The Lowry Lab at Michigan State University is searching for a postdoctoral research associate to conduct molecular and physiological experiments to understand the causes of genetic va...

I am currently searching for a new postdoctoral researcher to study the evolution, genetics, and physiology of cold acclimation and freezing tolerance in switchgrass at Michigan State University. This work will be funded by a newly funded five-year DOE grant. careers.msu.edu/jobs/researc...

Curator of Birds - Royal Ontario Museum - Career Page Apply to Curator of Birds at Royal Ontario Museum in Toronto, ON, Canada.

TWO curatorial positions at the Royal Ontario Museum, Toronto, ON, Canada. Curator of Birds, and Curator of Plants and Sustainability... please pass the word and amplify!

royalontariomuseum.applytojob.com/apply/XBR2Yc...

&

royalontariomuseum.applytojob.com/apply/Sf2iAO...

Rigorous validation of ecological models against empirical time series - Nature Ecology & Evolution Validating theoretical models against empirical data presents challenges. Here the authors present an assumption-light method to validate ecological models against time series data, along with a dedic...

Ecology faces an accumulation of models but not an accumulation of confidence. Our new paper w/ Jonathan Levine www.nature.com/articles/s41... in @natecoevo.nature.com introduces a rigorous test rooted in queueing theory to falsify inadequate models and build confidence in useful ones.

We have an open PhD position (application deadline 9 January 2026) in "Theory of fitness landscapes" at @unibe.ch 🤓⛰️📊👩‍💻🎓: banklab.github.io/positions/

Please share widely!

#QueerInSTEM #DisabledInSTEM #BlackInSTEM #WomenInSTEM #CarersInSTEM #AcademicSky #HigherED

I'm thrilled to be selected and grateful to be able to contribute to our community @official-smbe.bsky.social

Looking forward to new connections and future initiatives! @official-smbe.bsky.social @molbioevol.bsky.social @genomebiolevol.bsky.social

From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes Nature - A newly compiled atlas of species-wide structural variants and gene-based and graph pangenomes derived from highly complete assemblies of genomes from 1,086 natural isolates enable...

Incredible new paper from @schacherer.bsky.social et al rdcu.be/eLcTH

We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT

🚨🚨JOB ALERT 🚨🚨
Fresh new position in Comparative Biology at OSU!

We're looking for a comp. biologist, especially those who investigate biomechanics, functional anatomy, neuroanatomy, or morphological development.

Feel free to ask me any questions!
jobs.okstate.edu/jobs/assista...

Ichetucknee Springs State Park, a short drive from Gainesville, FL

The Hopkins Lab (hopkins-lab.com) at the University of Florida is looking to recruit a postdoc to work on the genetics of organ function and evolution across Drosophila and beyond. Please visit tinyurl.com/vcsjpmzz or email me for more info. And please RT or send to anyone who might be interested!

C. elegans is a real animal and we set out to understand how it comes to have its distinctive biogeography. Its ancestral center of diversity is in the higher elevation forests of Hawaii. Its closest relatives are spread across east Asia. Did they travel from Asia? [Preprint 🧵]

The Fitness Landscape: A Call for Papers Ruth Isaacson; The Fitness Landscape: A Call for Papers, Genetics, , iyaf206, https://doi.org/10.1093/genetics/iyaf206

Dear colleagues!

@davidmccandlish.bsky.social and I are serving as guest editors for the new special issue of GENETICS on fitness landscapes:

doi.org/10.1093/gene...

Submissions are due on March 18, 2026. Please spread the word! And reach out if you have questions.

Purple pollen visible in a dissected flower of Linum grandiflorum, flowering flax, an insect-pollinated species.

*Postdoc in Evolutionary genomics at Stockholm University*
We are recruiting a postdoc for a large interdisciplinary project to investigate evolutionary drivers and genomic consequences of pollen evolution in response to pollination mode shifts in flowering plants. 1/5

su.varbi.com/what:job/job...

Workshop: Novelty, Co-option and Divergence During Gene Network Evolution. Organisers: James Hombría and Antónia Monteiro. 14-17 June 2026, Buxted Park, East Sussex, UK. Early-career researchers apply for funded places.

Calling early-career developmental biologists!

Apply for a funded place at our #Workshop, Novelty, Co-option and Divergence During Gene Network Evolution.

Application deadline: 5 December

www.biologists.com/workshops/ju...

#DevBio #BiologistsWorkshops #Collaboration #Networking

Conference title: Dialectical Biology Today: Legacies of Richard Lewontin, and image of Lewontin in Black and White with intense expression in front of a chalkboard holding up a fist, When and Where Friday, October 10, 2025 11:30 am to Sunday, October 12, 2025 2:00 pm Music Room (218) Goldring Student Centre 150 Charles St W, Toronto, ON M5S 1K5 | and online via Zoom

I'm excited to share with you all a conference I'm planning Oct. 10-12: Dialectical Biology Today: Legacies of Richard Lewontin.

It will be hybrid in Toronto and on zoom, so please join us however you can! Register for zoom link here: ihpst.utoronto.ca/events/diale...

Adaptation is less accessible through mutations in promoters than in coding sequences when large effect sizes are needed Mutations within promoters and coding sequences are both involved in adaptation, but their relative contributions remain to be compared directly. Using the fungal enzyme cytosine deaminase, we examine...

Really excited to share our latest paper led by @simonaube.bsky.social. Fascinating results examining whether regulatory mutations can lead to adaptation as fast as coding mutations do. #mevosky #evobio #evoSky

www.biorxiv.org/content/10.1...

The new logo of Genome Biology and Evolution, featuring a phylogenomic circos network with a variety of organisms

We are proud to present the new logo of Genome Biology and Evolution! 🙌

Our new face reflects our continued commitment to serving the fields of genomics and evolutionary biology as a society journal belonging to @official-smbe.bsky.social

#genome #evolution #science #biology #societyjournal