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Deep Origin

@deeporigin.bsky.social

Better molecular modeling more scientists can use. We let scientists skip the sciOps. https://deeporigin.com

24 Followers  |  3 Following  |  17 Posts  |  Joined: 30.01.2025  |  1.4143

Latest posts by deeporigin.bsky.social on Bluesky

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Shout out to Deep Origin team member Aleks Grigoryan who wasn’t satisfied with just being proud of his team on the ground, but took it to the sky and made it loud! πŸš€ πŸͺ‚ 🧬

18.10.2025 09:57 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Donate to Support Kate's Recovery and Journey Back Home, organized by Matt Shlosberg Help Bring Kate Home to Heal Dear friends, We are reaching out wi… Matt Shlosberg needs your support for Support Kate's Recovery and Journey Back Home

One of our much loved team members (and an all around great human being) Kate was in a horrible accident. If you have the means or time to share or contribute to her recovery fund, you will be helping to make the world a brighter place:

gofund.me/9553c9134

25.09.2025 21:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A Blind Spot in Drug Discovery: Pocket Finding | Deep Origin It’s been said a million times before but it’s worth re-emphasizing. Creating. a. new. drug. is. hard.

In our new blog post, we dive into:
πŸ”Ί Limits of global docking models
πŸ”Ί False positives & cryptic pockets
πŸ”Ί How Deep Origin PocketFinder (in Balto) boosts accuracy
πŸ”Ί >80% success in recovering real binding sites

www.deeporigin.com/blog/a-blind...

25.09.2025 14:58 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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We're excited to be at #ARDD2025 β€” the premier conference focused on advancing therapies for aging and age-related diseases. As the field moves from breakthrough research to real-world impact, Deep Origin is here to explore the future of collab with biotech and pharma leaders shaping what comes next

04.08.2025 15:08 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Using our OncoSim toolkitβ€”combining ML + mechanistic models across 1,000+ cancer cell linesβ€”we’ve predicted 100+ novel synthetic lethal pairs. Some are validated and may guide therapy & resistance prediction.
Poster by Oliver Purcell @ GRCπŸ‘‡

www.deeporigin.com/academic-pos...

01.08.2025 13:39 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Feedback between F-actin organization and active stress governs criticality and energy localization in the cell cytoskeleton - Nature Physics Self-organized criticality can occur in cellular systems, but its origins remain unclear. Now it is shown that cytoskeletal criticality is influenced by the F-actin architecture and myosin active stre...

Thrilled to share our co-founder and CSO Garegin Papoian in Nature!

Actin cytoskeleton stores stress, unleashing sudden β€œcytoquakes”. Murrell @ Yale and Papoian @ UMD show orderly filaments diffuse force; tangled networks give power-law bursts.

Read more πŸ‘‰ nature.com/articles/s41567-025-02919-4

18.06.2025 16:58 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This summer, we're is opening its doors in Yerevan to curious, driven, and technically skilled students for a 10–12 week paid internship in biosimulations and protein modeling.

Starts: End of June
Location: Yerevan, Armenia
Duration: 10–12 weeks
Paid internship

apply.workable.com/deeporigin/j...

23.05.2025 10:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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We’ve developed a hybrid MM/NNP framework. It delivers high-accuracy solvation and binding Ξ”G predictions at an average throughput of ~600 ns/day on CPUβ€”10Γ— faster than GPU-based approaches.

Check out our scientific poster below πŸ‘‡

www.deeporigin.com/academic-pos...

12.05.2025 19:00 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
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Can AI Agents Design and Implement Drug Discovery Pipelines? The rapid advancement of artificial intelligence, particularly autonomous agentic systems based on Large Language Models (LLMs), presents new opportunities to accelerate drug discovery by improving in...

DO Challenge β€” is a new benchmark designed to test autonomous agentic systems in a resource-constrained, simulated drug discovery environment.

We applied it to our own agentic system, Deep Thought, comparing its performance against human teams.

See what we found πŸ‘‡

arxiv.org/abs/2504.19912

29.04.2025 12:42 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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We had a great time at #ACSSpring2025! From presenting posters, to hosting a great happy hour, to seeing what's new in chemistry, the energy in-person is great!

We'll share our posters in the coming days. For now, stay in the loop by joining our newsletter! www.deeporigin.com/newsletter

31.03.2025 18:59 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Deep Origin Challenge has wrapped up! This year we had over 40 teams made up of over 110 talented programmers, students, data scientists, and life scientists in a 10-hour-long prediction challenge at our Yerevan office πŸŒ„

Want to be involved next year? Stay informed πŸ‘‰ www.deeporigin.com/newsletter

28.03.2025 13:36 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Democratizing Drug Discovery - Deep Origin Happy Hour Β· Luma Are you attending ACS Spring and looking for cutting-edge, AI-powered solutions to advance your research? Join the Deep Origin team for an evening of tacos,…

Headed to American Chemical Society Spring '25 expo? Join us Monday night for tacos, drinks, swag and a chance to try out Balto - our AI assistant for drug discovery - with some of the most fun scientists around!

Register below πŸ‘‡

lu.ma/3sy7pqtb

17.03.2025 19:53 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Deep Origin Challenge 2025 Join us for the 2025 Deep Origin challenge

Last chance to sign up for the Deep Origin challenge!

πŸŒ„ A day-long AI/ML for drug discovery hackathon
🀝 Bring a team of up to 4 (or sign up yourself)
πŸ€– Meet and collaborate with leading ML and drug discovery experts
πŸ’΅ Compete for cash prizes

www.deeporigin.com/events/deep-...

11.03.2025 15:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Smart distributed data factory volunteer computing platform for active learning-driven molecular data acquisition - Scientific Reports Scientific Reports - Smart distributed data factory volunteer computing platform for active learning-driven molecular data acquisition

New pub from our team - check out our Smart Distributed Data Factory (think SETI@Home but for molecules) below πŸ‘‡

www.nature.com/articles/s41...

Want to download the DFT dataset or volunteer compute to create new DFT data points for the community? Find out more here: sddfactory.cloud

10.03.2025 16:30 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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Deep Origin Challenge 2025 Join us for the 2025 Deep Origin challenge

The #DeepOriginChallenge is back! Join us in our Yerevan office for a day of competition and collaboration building efficient #machineLearning models in small teams. Prizes up to $3k and the promise to meet leaders in AI and drug discovery.
Register below!

19.02.2025 14:40 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Aram Davtyan giving an awesome poster presentation about our work modeling protein-small molecule-protein ternary complexes at @keystonesymposia.bsky.social Proximity-Based Therapeutics! #biotech #drugDev #degraders #molecularGlues #PROTACs

Find the poster here: www.deeporigin.com/academic-pos...

18.02.2025 15:03 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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JPM β€˜25 From the Trenches: AI in Biotech Gets Tactical | Deep Origin Our take on the biggest trends and best observations at JPM '25

Miss #JPM? Not enough eyes and ears to take it all in? Here's our download of what's coming up in #biotech for 2025 πŸ‘‡

www.deeporigin.com/blog/jpm-25-...

30.01.2025 21:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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