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Chris Sundling

@chrissundling.bsky.social

Research group leader @Karolinskainst, working with immunoregulation in infectious diseases. B cells have a special place in my heart

614 Followers  |  1,063 Following  |  26 Posts  |  Joined: 27.10.2023  |  2.1841

Latest posts by chrissundling.bsky.social on Bluesky

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πŸ“£ We’re thrilled to announce the 5th Scottish Immunology Groups Network symposium! #SIGNET26

πŸ—“οΈ 11 March 2026
πŸ“ Perth, Scotland

A full day of cutting-edge research, collaboration & networking across the Scottish #Immunology community. Register here: https://bit.ly/3LxUJA5

11.11.2025 10:30 β€” πŸ‘ 10    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Postdoctoral Position in Infectious Diseases-Schaenman (PI) 2025-2026 University of California, Los Angeles is hiring. Apply now!

We are hiring a #Postdoctoral #Researcher to work in the Reed Lab @uclapathology.bsky.social on an exciting project dissecting impact of immunosuppression at the single cell level! Please reach out with any questions! @domucla.bsky.social #academicjobs #immunology recruit.apo.ucla.edu/JPF10679

10.11.2025 17:56 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

πŸ§ͺ Meeting will be in Keystone, CO March 16-20. Come for the skiing and the science!

#bcells #antibodies #immunosky #immunology

www.keystonesymposia.org/conferences/...

08.11.2025 01:37 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Oral Icotrokinra for Plaque Psoriasis in Adults and Adolescents | NEJM Icotrokinra, a targeted oral peptide that selectively binds the interleukin-23 receptor, is under investigation for the treatment of plaque psoriasis. We conducted a phase 3, double-blind, randomiz...

IL-23 is a highly targeted cytokine vs autoimmune disease.

But here with an oral agent!
@nejm.org #ImmunoSky #MedSky
www.nejm.org/doi/full/10....

05.11.2025 23:21 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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A multiplex Mtb-specific FluoroSpot assay measuring IFNΞ³, IL-2, and TNF-secreting cells can improve accuracy and differentiation across the tuberculosis spectrum | Journal of Clinical Microbiology Accurate diagnosis of Mycobacterium tuberculosis (Mtb) infection remains a cornerstone in tuberculosis (TB) control. Current interferon-gamma release assays (IGRAs) lack the ability to distinguish bet...

I realise the link did not work. Here is the correct link: journals.asm.org/doi/10.1128/...

30.10.2025 07:10 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Great collaborative team of lab and clincal researchers performing this study with lots of effort from excellent medical students and lab members building the cohort and performing experiments.

@ki.se @gunkal.bsky.social #Tuberculosis #Immunology @pucallpa.bsky.social @asm.org

29.10.2025 13:45 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

More specifically, very recent infection displayed reduced IFNg production and more geared towards IL2 and TNF while TB disease was associated with dual production of IFNg and TNF.

29.10.2025 13:45 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Key take homes: 1) measuring polyfunctional cells can increase assay specificity, 2) infection stage is associated with specific cytokine patterns

29.10.2025 13:45 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

New paper on detection of Mtb-specific T cell responses in TB infection and disease using a multiplex FluoroSpot (quantifying IFNg, IL2, and TNF).

journals.asm.org/eprint/CIH3C...

29.10.2025 13:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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#Openpositions #ImmunoSky #MedSky #wearehiring
Are you a postdoctoral researcher with an excellent track record in immunology research and/or a related field? Come and work with us in Finland!
πŸ‘‰Read more: bit.ly/43C68Fd

27.10.2025 07:25 β€” πŸ‘ 8    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Last week in #Science #Immunology: two papers from Bill Schief, Facundo Batista, @profshanecrotty.bsky.social, & al. provide evidence that simultaneous #immunization with multiple #bnAb #immunogens could be a viable #HIV #vaccine strategy!

Xie & al.
scim.ag/3W7wfQl

Sutton & al.
scim.ag/4ofvKQa

24.10.2025 17:18 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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The herpes simplex origin-binding protein: mechanisms for sequence-specific DNA binding and dimerization revealed by Cryo-EM Abstract. Herpes simplex viruses 1 and 2 (HSV-1,2) present growing treatment challenges due to increasing resistance to antivirals targeting viral DNA poly

New cryo-EM structures of HSV-1 origin-binding protein reveal how herpesvirus initiates DNA replication, offering new antiviral targets beyond DNA polymerase. Study published in
@narjournal.bsky.social πŸ§ͺ
academic.oup.com/nar/article/...

24.10.2025 13:55 β€” πŸ‘ 13    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

πŸ“’ Calling all early-career immunologists!

Are you passionate about #science-communication, #outreach and #editorial-strategy? The yEFIS-EJI working group is looking for you! 🫡

We’re recruiting motivated ECRs to contribute to editorial processes and creating content on yEFIS ECR activities ✍️

23.10.2025 13:25 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 1    πŸ“Œ 2
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πŸŽ‰ Congratulations to this year's SSI Young Investigator Award winners! Meet the rising stars of Scandinavian #immunology: John, Jonna, Chris, and AsbjΓΈrn @yssi-immunology.bsky.social @yefis-immunology.bsky.social @efis-immunology.bsky.social @iannaconelab.bsky.social @romagnanilab.bsky.social

16.10.2025 09:21 β€” πŸ‘ 17    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0
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The #Scandinavian SSI #Immunology meeting has come to an end. Is has been 3 days full with amazing science from invited speakers, selected short talks, poster presentations, and social and network opportunities!

We already look forward to the meeting in #Bergen!

@ssi-immunology.bsky.social

17.10.2025 10:59 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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What a way to wrap up the first day of the 50th Annual Meeting of the Scandinavian Society of #Immunology @ssi-immunology.bsky.social Dinner and drinks at the very same venue where #Nobel laureates soon will be celebrating their achievements #gyllene rummet #Stockholm City Hall

15.10.2025 19:44 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Exciting #SSI2025 meeting starting today

15.10.2025 07:05 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Midlands Integrative Biosciences Training Partnership - University of Birmingham MIBTP is a UK-wide doctoral training programme that equips bioscience PhD students with interdisciplinary skills to tackle global challenges in agriculture, health, and sustainability.

Fancy doing a PhD on #fungi ? πŸ„ I'm co-supervising a project on the MIDTP program with Dr Ayesha Rahman - follow the link for project details and how to apply! #FindAPhD #immunosky πŸ§ͺ
www.birmingham.ac.uk/about/colleg...

14.10.2025 13:04 β€” πŸ‘ 14    πŸ” 12    πŸ’¬ 0    πŸ“Œ 1
Concept image from Getty Images, defence against the coronavirus

Concept image from Getty Images, defence against the coronavirus

A new KI study published in Nature Immunology shows that CD56bright #NKcells temporarily reside in our organs and then leave them via the lymphatic system. The results change our understanding of how the immune system works in human organs. #Immunology πŸ§ͺ news.ki.se/the-immune-s...

14.10.2025 14:38 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Thank you for reading and enjoying it πŸ™

14.10.2025 11:01 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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We are recuiting a postdoc to join us at The University of Oslo. The candidate will investigate how T cells in the Germinal Center shape B cell and antibody quality. The projects include intravital 2-photon microscopy!

www.jobbnorge.no/en/available...

13.10.2025 20:44 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Tuberculosis Preventive Treatment for Pregnant People With HIV in South Africa: A Modeling Analysis of Clinical Benefits and Risks Although prior studies of tuberculosis-preventive treatment (TPT) for pregnant people with human immunodeficiency virus (PPWH) report conflicting adverse pregnancy outcome (APO) risks, international guidelines recommend TPT for PPWH.

Tuberculosis Preventive Treatment for Pregnant People With HIV in South Africa: A Modeling Analysis of Clinical Benefits and Risks

#IDSky

12.10.2025 22:31 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 7

Bubbles impacting laser delay

13.10.2025 04:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

#MedskyπŸ§ͺ #IDsky #immunosky #virosky #Publichealth Based on a study in @sciimmunology.bsky.social , a #covid booster immunization drives a germinal center mediated broadening of #Bcell responses by recalling existing #memoryBcells

10.10.2025 20:00 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
Bubble Chart displaying the different types of antigens targeted by B cells in the papers in the database so far. Antigens are grouped into the the viruses, bacteria, parasites, plants, animals, or other sources they come from. And the bubble sizes are scaled to represent how frequently those antigens have been used

Bubble Chart displaying the different types of antigens targeted by B cells in the papers in the database so far. Antigens are grouped into the the viruses, bacteria, parasites, plants, animals, or other sources they come from. And the bubble sizes are scaled to represent how frequently those antigens have been used

A few years ago, my lab started a list of papers analyzing antigen-specific #Bcells w/ fluorescent probes via #flowcytometry. We are now releasing this list of 700+ papers as a searchable database on my lab website with a short overview. www.biorxiv.org/content/10.1...

10.10.2025 14:29 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 2    πŸ“Œ 0

From the now published pan-disease blood atlas, we used the proteomic data together with clinical and single-cell data to describe immune cross-talk linked with disease severity in malaria @cp-immunity.bsky.social

Check it out!

www.sciencedirect.com/science/arti...

#Immunology #malaria @ki.se

10.10.2025 14:37 β€” πŸ‘ 9    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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A human pan-disease blood atlas of the circulating proteome The human blood proteome provides a holistic readout of health states through the assessment of thousands of circulating proteins. Here, we present a pan-disease resource to enable the study of divers...

New study on a human pan-disease proteomic blood atlas out in @science.org! www.science.org/doi/10.1126/.... The resource is available at the human protein atlas website: www.proteinatlas.org/humanproteom...

#immunology #Health #Disease @ki.se @scilifelab.se @peternilsson-kth.bsky.social

10.10.2025 14:30 β€” πŸ‘ 15    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
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To celebrate this year’s #NobelPrize in #Medicine, awarded for the discovery of regulatory #TCells, we have selected 8 papers recently published in #Science #Immunology that highlight recent advances in #Treg biology! The collection will be online until the end of Oct 2025!

bit.ly/SciImm_free

09.10.2025 17:43 β€” πŸ‘ 14    πŸ” 4    πŸ’¬ 1    πŸ“Œ 1

yEFIS Career webinars are back! #ImmunoSky #career #science

09.10.2025 22:28 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

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