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Stephen Malina

@an1lam.bsky.social

Machine learning aided protein carpenter, cat enthusiast

119 Followers  |  99 Following  |  16 Posts  |  Joined: 29.04.2023
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Posts by Stephen Malina (@an1lam.bsky.social)

( (creator:[Hughes, Sally Smith])) - Search Results - Digital Collections Digital Collections Search Results.

A treasure trove of biotech and early SV oral histories by Sally Hughes: digicoll.lib.berkeley.edu/search?p=%28...

Genentech (Boyer, Goeddel (recommended!)), VC (Byers, Rock, Valentine), Kaiser ("History of the Kaiser Permanente Medical Care Program"), Lilly, Paul Berg, Stan Cohen, lots more.

30.10.2025 00:54 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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Medicinal chemists be like:

21.02.2025 13:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

It does feel like it could both enable better sousveillance but also create panopticon dynamics at a level not previously experienced. Think Rainbow's End but with even cheaper sifting/monitoring.

15.02.2025 18:13 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Some professional news: the best way to do large scale data processing in native python using pandas/ numpy now open source; Bodo runs 20-240x faster than others like Spark, Dask, and Ray (see benchmark in repo).

github.com/bodo-ai/Bodo

17.12.2024 17:18 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

How do you feel about this but the OSint flavored version?

29.11.2024 15:09 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Despite recently learning the story of the real Rayleigh from this great article (press.asimov.com/articles/mea...), I confess that there's only room for one Rayleigh in my heart and it's him:

29.11.2024 15:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Is there a game capturing the fundamentals of capital allocation remotely as well as Factorio does process optimization?

28.11.2024 16:48 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

"And so Gutenberg's holdouts, confined to the artisanal dustbin of history, went out with a wimper rather than a bang..."

29.11.2024 14:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

If we ever build agents tasked with holding politicians and policymakers' public statements to account, finding contradictions, inconsistencies, failed targets, missed promises etc. we'll be in a much better position. Some quick thoughts:

25.11.2024 12:31 β€” πŸ‘ 15    πŸ” 2    πŸ’¬ 3    πŸ“Œ 1

The most blatantly self-serving article I've seen in recent memory. The reason for loss of public trust in science is… that we don't treat editors with enough respect? Yes, editors should be respected. No, that has nothing to do with loss of trust. 1/2

02.02.2024 14:29 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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Real free speech absolutism is Phil Zimmerman publishing PGP as a book to avoid export controls against the will of the US government. Or DJB fighting multiple court cases (https://en.m.wikipedia.org/wiki/Bernstein_v._United_States) in order to be able to publish cryptographic source code.

05.06.2023 13:02 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Fraudulent data raise questions about superstar honesty researcher Dan Ariely denies fabricating data, but can’t produce records to clear his name

Ariely also is not necessarily trustworthy...

https://www.science.org/content/article/fraudulent-data-set-raise-questions-about-superstar-honesty-researcher

16.05.2023 02:34 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

One thing I increasingly appreciate (or find grating) about certain sci-fi authors is when they have characters that are supposedly much more capable actually use that competence in important situations. Neal Asher, Greg Egan, and Peter Watts all have super different styles but are all good at this.

08.05.2023 02:12 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Some of you may not know this but I'm part of an esoteric sect of May the Fourth celebrators who thinks Admiral Ackbar was the real hero. We call ourselves Monmons.

05.05.2023 00:17 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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He brought bamboo

04.05.2023 22:53 β€” πŸ‘ 40    πŸ” 6    πŸ’¬ 3    πŸ“Œ 1
Red panda with his tongue out

Red panda with his tongue out

Moshu’s here

04.05.2023 22:36 β€” πŸ‘ 342    πŸ” 80    πŸ’¬ 30    πŸ“Œ 32

Physical work has its own focus inducing properties but at least for me they're not nearly as potent as being in the programming zone.

03.05.2023 12:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

On the margin, I think people overestimate how much salary drives engineers to work on software and underestimate the power of feedback loops and low barriers to entry (not in a physical not economic sense). There's a reason the workplace stereotype of someone in flow started with programmers.

03.05.2023 12:10 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I also will totally bite the bullet on the thought experiments. Yes if you cloned my consciousness at least initially that person would be no different than me and this would hold weight (e.g. I'd give them half my $$). We'd diverge over time due to different experiences though.

03.05.2023 12:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Future you is probably way more similar to past you than you are to anyone on Earth if for no other reason than because future you proceeded from the thought train of past you. (Or at least I think this is true of me.)

03.05.2023 11:45 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Controversial philosophy opinion: I think people overrated the practical force of Parfit's argument against persistent identity. It's true that your identity doesn't have some special essence tying it together but people are a super high dimensional space.

03.05.2023 11:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Missed opportunity for: caffeine is low key GOATed when tolerance reset is the vibe

03.05.2023 11:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Next comes the bug delicacies

30.04.2023 14:22 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0