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Adam Gracz

@graczlab.bsky.social

Genetic regulation of cell identity and regeneration | All things gut & liver | πŸ³οΈβ€πŸŒˆ | Opinions are my own | he/him/his www.graczlab.org

1,799 Followers  |  967 Following  |  87 Posts  |  Joined: 11.11.2023  |  1.9405

Latest posts by graczlab.bsky.social on Bluesky

Great department, great institution, wonderful colleagues! This is an outstanding opportunity

30.09.2025 18:51 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

My department at Emory is a hiring a tenure-track neuroscientist!

Anyone who's talked to me in the last 4 years knows I cannot say enough good things about my dept and the neuroscience community here. My colleagues are so wonderfully supportive. Postdocs, please apply!

apply.interfolio.com/174371

30.09.2025 18:25 β€” πŸ‘ 125    πŸ” 97    πŸ’¬ 1    πŸ“Œ 5

We initiated this open letter yesterday, before the solicitation came out. We made an update this morning, and are working on additional response and actions focused on the eligibility change.

Please sign and share the letter if you can! And add an email for updates.

bsky.app/profile/jaso...

26.09.2025 22:51 β€” πŸ‘ 6    πŸ” 7    πŸ’¬ 0    πŸ“Œ 2

This was (horrible) news to me. Took a few minutes to sign - you should too!

25.09.2025 23:17 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Faculty Professor Associate - Full-Time | Vaughn Cooper We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine. 1) Fundamental researc...

🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
πŸ”— to all 3 w/info: www.linkedin.com/posts/vaughn...

23.09.2025 22:31 β€” πŸ‘ 93    πŸ” 127    πŸ’¬ 1    πŸ“Œ 6

Any academic folks on H1B visas (even with stamps in passports) please get legal advice from your University attorneys before leaving the US.

20.09.2025 04:09 β€” πŸ‘ 288    πŸ” 135    πŸ’¬ 8    πŸ“Œ 4

β€œThis isn’t just about 211 missing R01 grants. This is about the 211 PIs (or multi-PI groups) that are not getting a new grant. This is about at least 422-844 non-PI level investigators who are not having their salaries covered.”

09.09.2025 19:36 β€” πŸ‘ 41    πŸ” 20    πŸ’¬ 2    πŸ“Œ 1

Just heard from someone who had a 1% grant not funded through NIMH.

Why?

Perhaps no payline for 2026?

2025 all full up?

Unclear. But totally bonkers and indicative of the complete gutting of the NIH/NIMH senior and grants processing peeps.

The ones who remain are working so hard.

09.09.2025 01:04 β€” πŸ‘ 49    πŸ” 10    πŸ’¬ 6    πŸ“Œ 1

πŸ§ͺ And House appropriators say: no cuts to NIH budget!

House subcommittee version just came out (link below). Holds NIH flat at $48 billion.

To be clear: this is far from over. But a good sign that science still matters across both sides of aisle.

YOUR VOICE MATTERS!!

01.09.2025 22:37 β€” πŸ‘ 466    πŸ” 179    πŸ’¬ 5    πŸ“Œ 12
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Administrative burden in Australian universities: Insights into dimensions and drivers from a nationwide survey Abstract. Despite widespread concern about levels of administrative burden within universities, understanding of the associated dimensions and drivers rema

This is an important read for those universities whose leadership is increasingly from a business background and are pushing for β€œoptimization”.

Article is here: academic.oup.com/spp/advance-...

29.08.2025 11:35 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
Bob's burger meme: I hope everyone's having a good time, and if you're not, I'd like to see you organize something on this budget and in this time frame.

Bob's burger meme: I hope everyone's having a good time, and if you're not, I'd like to see you organize something on this budget and in this time frame.

My forever meme.

29.08.2025 10:49 β€” πŸ‘ 28    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Pediatric Brain Cancer Trial Group to Be Phased Out

"Pediatric Brain Cancer Trial Group to Be Phased Out"

"A network of hospitals and cancer centers dedicated to early phase trials of novel treatments will no longer receive federal funding."

πŸŽπŸ”—

Nina Agrawal for @nytimes.com

29.08.2025 01:48 β€” πŸ‘ 1190    πŸ” 855    πŸ’¬ 101    πŸ“Œ 170
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Transient gene melting governs the timing of oligodendrocyte maturation Oligodendrocyte maturation is governed by an SOX6-dependent gene-melted chromatin state at multiple immaturity loci. Reducing SOX6 accelerates maturation, offering a potential strategy to regenerate myelin in diseases like multiple sclerosis.

Now online! Transient gene melting governs the timing of oligodendrocyte maturation

25.08.2025 14:59 β€” πŸ‘ 8    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

SCOTUS decision "in a scientific sense...a total loss"

"Years long studies will lose validity...Lifesaving medication trials will be abandoned. Countless researchers will lose their jobs.”https://www.nature.com/articles/d41586-025-02721-5

23.08.2025 13:46 β€” πŸ‘ 15    πŸ” 6    πŸ’¬ 0    πŸ“Œ 2
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Aria Huang's @azyhuang.bsky.social paper is out on beautiful embryonic kidney 3D cultures that branch properly and enable live defect analysis. She also finds intriguing effects of adhesion and stiffness on explant size, shape, and nephron formation - boundary conditions matter!

rdcu.be/eBSUK

22.08.2025 15:46 β€” πŸ‘ 32    πŸ” 11    πŸ’¬ 0    πŸ“Œ 2
Promotional graphic for a special issue of the Journal of Experimental Biology titled "The Integrative Biology of the Gut." Guest editors are Carol Bucking, Matt Regan, and John Terblanche. The artwork features a stylized gut with segments representing diverse ecosystemsβ€”desert, forest, and riverβ€”symbolising the environmental and biological complexity of gut research. The journal’s logo appears in the bottom left corner.

Promotional graphic for a special issue of the Journal of Experimental Biology titled "The Integrative Biology of the Gut." Guest editors are Carol Bucking, Matt Regan, and John Terblanche. The artwork features a stylized gut with segments representing diverse ecosystemsβ€”desert, forest, and riverβ€”symbolising the environmental and biological complexity of gut research. The journal’s logo appears in the bottom left corner.

New special issue from Journal of Experimental Biology

This issue considers the functional roles of the #gut, from the #cellular level to its interactions with other #organs and tissues, including its role in #ecophysiological and #biogeochemical processes.

journals.biologists.com/jeb/issue/22...

21.08.2025 12:28 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
People were not healthier 60 years ago.
YouTube video by Andrea Love, PhD People were not healthier 60 years ago.

People weren’t healthier β€œback in the day.”

In 1960s, life expectancy was in the 60s vs. 79 today.

Testicular cancer? 95% fatal.
Today? 95% survivable.

Same with MANY cancers.
Infections. Vaccine-preventable illness.

We live longer & healthier lives today bc of science.

youtu.be/rDx7LrBiMH0?...

18.08.2025 00:46 β€” πŸ‘ 706    πŸ” 263    πŸ’¬ 24    πŸ“Œ 8

5. It has been centuries since any one human could know everything that is known; understand everything that is understood.

This is a remarkable power of science. We delegate trust and authority to experts as internally established in ways that are remarkably resilient to mistakes and malfeasance.

12.08.2025 05:00 β€” πŸ‘ 1115    πŸ” 171    πŸ’¬ 5    πŸ“Œ 16
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These are the most challenging times for early-career scientists and engineers.

My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.

We found 437 of them.

Download it freely here: research.jhu.edu/rdt/funding-...

11.08.2025 11:54 β€” πŸ‘ 312    πŸ” 200    πŸ’¬ 6    πŸ“Œ 3
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Dishevelled-1 regulates global transcriptomic changes and associates with ETS1 transcription factor Nature Communications - Currently, nuclear roles for DVL1 and its involvement in gene regulation remained unclear. Here the authors reveal that altering DVL1 expression significantly reshapes gene...

For years, we searched for factors which are dysregulated in cancer and regulate development. We now describe elusive roles of DVL, a protein co-opted in #cancer and mutated in congenital disorders thanks to lab members & support from @unclineberger.bsky.social & @unc-phco.bsky.social
rdcu.be/ewwsZ

16.07.2025 18:25 β€” πŸ‘ 74    πŸ” 14    πŸ’¬ 3    πŸ“Œ 0

Requests that were previously submitted via the prior approval module will not be reviewed, and recipients will need to initiate the first no cost extension within the Status module by using the Extension action

09.08.2025 11:49 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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The updated version of the database of PhD fellowships produced and maintained by my team can be downloaded by anyone here:

research.jhu.edu/rdt/funding-...

For each of the 187 fellowships, you will find a short description, deadline, $ amount, link, etc.

Good luck!

08.08.2025 10:58 β€” πŸ‘ 77    πŸ” 53    πŸ’¬ 0    πŸ“Œ 1
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Improving Oversight of Federal Grantmaking By the authority vested in me as President by the Constitution and the laws of the United States of America, and to improve the process of Federal

1. Federal funding for research promotes tech, biomedical, and scientific discovery in the US, and provides training for the sci/tech workforce that has brought immeasurable wealth to the US over the past 75 years.

Today's executive order includes a provision that will obliterate both functions.

08.08.2025 01:13 β€” πŸ‘ 1008    πŸ” 547    πŸ’¬ 25    πŸ“Œ 76

…starting to see tariff charges come through on ordering reagents for the lab. Not a great feeling πŸ˜‘

07.08.2025 12:04 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut Senators from both parties endorsed a $400 million increase to the budget of the National Institutes of Health on Thursday

Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut www.statnews.com/2025/07/31/n...

31.07.2025 21:08 β€” πŸ‘ 138    πŸ” 36    πŸ’¬ 2    πŸ“Œ 3
NOT-OD-25-138: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs NOT-OD-25-138. NIH

NIH wants to hear from you. No really.

Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs
grants.nih.gov/grants/guide...

31.07.2025 03:21 β€” πŸ‘ 64    πŸ” 53    πŸ’¬ 9    πŸ“Œ 9

100% this. Is it even possible to run a journal on an exclusively OA model with APCs under about $2-2.5k?

31.07.2025 11:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I’ve honestly struggled to believe that OA is such an important hill to die on. We don’t write for the general public. As an ideology I’m 100% behind it, but practically I’d rather we pay $1-1.5k for a subscription model where papers are deposited in PMC after a 1yr embargo.

31.07.2025 11:28 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I was thinking about this too as I'm a standing member at NIH and review did the DoD. The amount of time and effort for no monetary benefit that is expected of us is unreasonable even at a 10th percentile funding rate. But at 4%.... what are we even asking of scientists?

28.07.2025 03:50 β€” πŸ‘ 26    πŸ” 10    πŸ’¬ 1    πŸ“Œ 1

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