Adam Gracz

Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut Senators from both parties endorsed a $400 million increase to the budget of the National Institutes of Health on Thursday

Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut www.statnews.com/2025/07/31/n...

NIH wants to hear from you. No really.

Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs
grants.nih.gov/grants/guide...

100% this. Is it even possible to run a journal on an exclusively OA model with APCs under about $2-2.5k?

I’ve honestly struggled to believe that OA is such an important hill to die on. We don’t write for the general public. As an ideology I’m 100% behind it, but practically I’d rather we pay $1-1.5k for a subscription model where papers are deposited in PMC after a 1yr embargo.

I was thinking about this too as I'm a standing member at NIH and review did the DoD. The amount of time and effort for no monetary benefit that is expected of us is unreasonable even at a 10th percentile funding rate. But at 4%.... what are we even asking of scientists?

One doesn’t even need an altruistic or idealistic view of science to believe that gutting scientific research is a bad idea.

Nations invest in basic research because innovation fuels modern economies and global leadership. And it costs pennies compared to more frivolous govt spending

few outcomes, except for 99% of FDA-approved drugs, 174 recipients of 104 Nobel Prizes, training ~30K MDs and ~10K PhDs per year to enter the workforce, and a 34% reduction in age-adjusted cancer deaths since 1990 -- the largest decrease in history

The NIH was healthiest when pay lines were in the 20th percentile range.

We are headed into an environment where pay lines are in the 5% range.

In my entire career, I’ve only had 3 grants that scored better than 5%. And my lab is considered a successful one.

This is going to destroy science.

I doubt that there is a single family in America that hasn’t benefitted directly from the NIH.

If you are an "FFPE expert", could I ask you a few questions?

Let me know and I'll DM you 😊

Please RT

expect a 50 to 75% cut in all institute paylines (already tight — NCI’s was 9%) — meaning 50 to 75% of labs that were competitively funded on merit go dark and shut down

BRENNAN: Are you going to release the cancer research funding?

RUSS VOUGHT: We're gonna continue to go through the same process that we have gone through with regard to the Dept of Education & we will release that funding when we are done


BRENNAN: The WH budget does call for a $18b cut to NIH

TAPPER: 14 Republicans say you're risking undermining critical research by holding up NIH funding

VOUGHT: If they were a company, their stock price would in shambles. They in some respects caused the pandemic. You have an entire institute that does nothing more than DEI research at the NIH.

In light of today’s news about the National Cancer Institute announcing a 4% payline, it’s really important to communicate to people that the previous 10% payline was still effectively a lottery and the result of decades of underfunding the NIH. Paylines used to be 25%.

This is a(nother) disaster for science in the US

No better time to call or email your members of Congress. Next year’s NIH budget is being debated in the Senate. A new nonpartisan campaign is making it easy to defend science and protect America’s innovation. Just follow this link to contact your representatives: www.protectscienceandinnovation.org

Really enjoyed reading this - compliments to all of the authors! Truly impressive use of transgenic human organoids but also an enjoyable and approachable paper to read.

…and we should really all be preprinting manuscripts at time of submission and freely sharing articles with colleagues who inquire.

My Friday afternoon hot take is that open access is well-intentioned but an enormous waste of $. Research articles aren’t written for general understanding.

The $1000s spent on OA APCs could probably hire a science writer (or AI model) to draft a short lay summary.

Can’t wait to read this one!

Does anyone have an example of a successful F31 under the new format?

Grant terminations have grabbed the headlines and have seen legal action, but even more damaging to the US research enterprise has been the massive decrease in number of research grants issued by federal agencies

NIH has seen a decrease of 57% in the number of awards & 63% in value compared to FY24

what if i'm not good enough to have imposter syndrome

Why We Still Need Animal Research in a World of AI and Organoids The portrayal of uncaring scientists without any thought for the animals being used in their research is far from the truth.

www.genengnews.com/topics/trans...

Yesterday a Senate subcommittee said no to proposed slashes to NASA & NSF funding.

Today, Thursday, the full Senate Appropriations Committee meets. The members of the committee are from the states below.

Keep the pressure on! Give them a call. Search “call my Senator” or call (202) 224-3121.

Time to call and write to these members.

📢 Bluesky is emerging as the New Platform for Academia, but what's missing?

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This is devastating for early discovery research and all of the (very very many) phenomena that are simply impossible to accurately model with even the most advanced in vitro platforms. And I say that as an enthusiastic advocate of organoid research.

Range extender mediates long-distance enhancer activity - Nature The REX element is associated with long-range enhancer–promoter interactions.

Our paper describing the Range Extender element which is required and sufficient for long-range enhancer activation at the Shh locus is now available at @nature.com. Congrats to @gracebower.bsky.social who led the study. Below is a brief summary of the main findings www.nature.com/articles/s41... 1/

Excited for a packed day of science at the inaugural Cholestatic Liver Disease Summit!