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Ivaska Lab

@ivaskalab.bsky.social

Research group interested in everything around cancer and integrins (more details on our website!). Posts by Ivaska Lab members. Website: https://ivaskalab.utu.fi/

913 Followers  |  270 Following  |  14 Posts  |  Joined: 19.11.2024  |  1.8175

Latest posts by ivaskalab.bsky.social on Bluesky

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EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different c…

Latest from Ivaska Lab ▶️ Niklas Jäntti et al delve deep into the roles of EPLINα/β on integrin trafficking and breast cancer outcomes!

Congratulations to all the authors!

Check the paper out here: www.sciencedirect.com/science/arti...

16.07.2025 07:55 — 👍 10    🔁 3    💬 0    📌 0
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EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different c…

Excited to share our most recent study on #integrintraffic #cancer #migration #focaladhesion by @ivaskalab.bsky.social @drpaulinamoreno.bsky.social Niklas Jäntti et al www.sciencedirect.com/science/arti...

16.07.2025 07:26 — 👍 33    🔁 14    💬 1    📌 0
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If you are at the FEBS Congress in Istanbul and would like to have a chat about adhesion-derived protein condensates come to see my poster today between 12:30-13:45. Looking forward to inspiring discussions! 🔬

@ivaskalab.bsky.social

07.07.2025 08:15 — 👍 6    🔁 2    💬 0    📌 0

Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!

23.06.2025 14:29 — 👍 66    🔁 87    💬 0    📌 7
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MI/25/33 - Postdoctoral Scientist Systems Oncology Group | Cancer Research UK Manchester Institute Add brief description here

We are looking for a postdoctoral fellow to come work with us: www.cruk.manchester.ac.uk/career/mi-25... Please reach out

07.06.2025 09:57 — 👍 9    🔁 11    💬 0    📌 0

1/ Beyond thrilled to see my #PhD work now published in @jcb.org
A short thread (🧵) for #metastasis #metabolism #ExtracellularVesicles (EVs) aficionados

09.06.2025 20:22 — 👍 35    🔁 11    💬 1    📌 4
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Uusi koetin tekee näkyväksi syöpäsolun viestinnän, tutkijat voivat käyttää tietoa rintasyövän leviämisen estossa Turun yliopistossa ja Turun biotiedekeskuksessa toimiva tutkimusryhmä on kehittänyt tavan kuvata leviävien rintasyöpäsolujen soluviestintää.

Miten syöpäsolut leviävät ja voidaanko sitä estää? Toistaiseksi ei, mutta tämä saattaa muuttua. Turun biotiedekeskuksen tutkijat löysivät keinon avata syöpäsolujen viestintää, ja tämän tiedon kautta saattaa löytyä lääke syöpäsolujen pysäyttämiseen.

@ivaskalab.bsky.social @johannaivaska.bsky.social

02.06.2025 12:55 — 👍 11    🔁 3    💬 0    📌 1
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New visualisation tool helps researchers to target breast cancer dissemination Cancer cell movement during metastasis is a dynamic process regulated by several different signals.

Signaling networks inside #cancer cells control everything from growth to movement, but visualising this in living cells requires new and refined methods. Researcher James Conway set out to see these invisible signals and came up with a new tool to do just that.
#Illusia
@ivaskalab.bsky.social

02.06.2025 13:02 — 👍 4    🔁 1    💬 0    📌 0
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Uusi koetin tekee näkyväksi syöpäsolun viestinnän, tutkijat voivat käyttää tietoa rintasyövän leviämisen estossa - InFLAMES-lippulaiva Turun yliopistossa ja Turun biotiedekeskuksessa toimiva tutkimusryhmä on kehittänyt tavan kuvata leviävien rintasyöpäsolujen soluviestintää. Menetelmä on paljastunut, että muihin syöpätyyppeihin parha...

Syövän nykyisillä lääkkeillä ei voida estää syövän leviämistä. Tilanne saattaa muuttua, sillä tutkijamme ovat kehittäneet tavan kuvata syöpäsolun sisäistä signalointia, joka on edellytys solun liikkumiselle.
#Illusia
@johannaivaska.bsky.social @ivaskalab.bsky.social @turkubioscience.bsky.social

03.06.2025 11:12 — 👍 3    🔁 3    💬 0    📌 0
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New visualisation tool helps researchers to target breast cancer dissemination - InFLAMES Research Flagship Cancer cell movement during metastasis is a dynamic process regulated by several different signals. However, the way cells receive, process and respond to these signals has been extremely hard to dete...

In a new study led by InFLAMES PI Professor Johanna Ivaska and Dr James Conway have developed a new fluorescent probe to visualise signaling dynamics in moving cancer cells which they used to uncover a new therapeutic possibility for limiting breast cancer spread.
#Illusia
@ivaskalab.bsky.social

03.06.2025 11:17 — 👍 9    🔁 3    💬 0    📌 0
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New paper from @ivaskalab.bsky.social out now! 🍾 Watch how cancer cell adhesion dynamics are disrupted by inhibiting the phosphatase Shp2 - key to integrin β1 phosphorylation. Blocking Shp2 impairs adhesion and reduces invasion potential. 🎥👇 Read more at: www.nature.com/articles/s41...

26.05.2025 10:29 — 👍 29    🔁 15    💬 1    📌 0
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Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells - Nature Cell Biology Conway et al. show that integrin β1 phosphorylation is regulated through balanced activities of tyrosine kinases, such as Src and Arg, and phosphatases, such as PTP-PEST and Shp2, facilitating invadop...

Latest from @ivaskalab.bsky.social @jrwconway.bsky.social in NCB. We find that SHP-2 inhibition stops TNBC invasion and limits metastasis by blocking integrin dephosphorylation!

Read more at:

www.nature.com/articles/s41...

26.05.2025 12:16 — 👍 31    🔁 9    💬 0    📌 0
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Our newest paper is out in NCB. @jrwconway.bsky.social‬ designed a new FRET reporter, Illusia, to show the importance of integrin β1 phosphorylation dynamics in 3D invasion! Video: TNBC cells expressing Illusia with a Src (Saracatinib) or SHP2 (SHP099) inhibitor. www.nature.com/articles/s41...

26.05.2025 10:13 — 👍 39    🔁 10    💬 0    📌 0
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Syöpätutkija Johanna Ivaskalle 100 000 euron tiedepalkinto Ivaskan työryhmä tutkii syöpäsolujen liikkumista ja leviämistä.

www.is.fi/kotimaa/art-...

Great recognition to @ivaskalab.bsky.social research at @turkubioscience.bsky.social the Finnish Science Prize
thanks to all my international friends and colleagues over the years

20.05.2025 15:46 — 👍 27    🔁 2    💬 2    📌 0

We are very proud to announce @johannaivaska.bsky.social as the recipient of the Biennial Finnish Science Award, given by the Finnish Ministry of Education & Culture. Johanna was described as a distinguished researcher with pioneering work in cell biology. Warmest congrats from all of us, boss!

20.05.2025 10:32 — 👍 33    🔁 4    💬 1    📌 1
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Honored to have been elected with Patrick Caswell @mcrcellmatrix.bsky.social co-chair of the 2029 Gordon Research Conference on Fibronectin, Integrins, and Related Molecules!
We have big shoes to fill: www.grc.org/fibronectin-..., but are up for the challenge!

12.05.2025 13:18 — 👍 26    🔁 7    💬 1    📌 0
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Adhesion-derived condensates control component availability to regulate adhesion dynamics Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a m...

New preprint alert!📣 @midibu.bsky.social and team take a deep dive into Tensin1 liquid-liquid phase separation (LLPS) and the mechanisms of how it regulates adhesion dynamics!
Check out the preprint here: www.biorxiv.org/content/10.1...
@johannaivaska.bsky.social

10.05.2025 07:37 — 👍 18    🔁 6    💬 0    📌 1
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Adhesion-derived condensates control component availability to regulate adhesion dynamics Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a m...

Happy to share our Tensin 1 phase separation project is now on bioRxiv.
www.biorxiv.org/content/10.1...

This wouldn't be possible without
@johannaivaska.bsky.social
@ivaskalab.bsky.social
#VattulainenLab
#MSCA by @ec.europa.eu
@turkubioscience.bsky.social
@inflames-flagship.bsky.social

09.05.2025 14:23 — 👍 29    🔁 18    💬 3    📌 1
A graphic for the Marie Skłodowska-Curie Actions (MSCA), showing a historical portrait of Marie Skłodowska-Curie overlaid with an image of four young researchers walking down a hallway. The European Commission logo is in the top left. Text reads: "Marie Skłodowska-Curie Actions – €404.3 million to support postdoctoral researchers”

A graphic for the Marie Skłodowska-Curie Actions (MSCA), showing a historical portrait of Marie Skłodowska-Curie overlaid with an image of four young researchers walking down a hallway. The European Commission logo is in the top left. Text reads: "Marie Skłodowska-Curie Actions – €404.3 million to support postdoctoral researchers”

Choose Science. Choose Europe.

A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.

With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.

Apply by 10 September → europa.eu/!fBTMgF

08.05.2025 10:12 — 👍 962    🔁 565    💬 15    📌 99
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Kohde Pharma Oy Secures Investment from Finnish Drug Discovery Center Ltd - Finnish Drug Discovery Center Vantaa, Finland – May 8th 2025 – Kohde Pharma Oy, a newly incorporated pharmaceutical company in Finland, is pleased to announce that it has secured its first investment from Finnish Drug Discovery Ce...

Very important milestone for Finnish academic drug development. The recently established Finnish Drug Development Center has started its first drug development project in collaboration with a start-up Kohde Pharma. ddcenter.fi/kohde-pharma...

08.05.2025 10:27 — 👍 4    🔁 1    💬 0    📌 0
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On my way home after 3 days full of great talks and lively discussions at Fort-Mahon-Plage. Thank you @clubexo-endo.bsky.social community, I had a blast!

07.05.2025 21:24 — 👍 8    🔁 3    💬 0    📌 0

I'm at the Fibronectin GRC till the end of the week! Come say hi and I'll tell you a bit about mitochondrial near focal adhesions😉

07.05.2025 06:50 — 👍 9    🔁 1    💬 0    📌 0
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Currently at Fibronectin and Integrins GRC in Italy, meeting amazing people and discussing great science. If you are interested in Tensin phase separation, come and talk to me!
@ivaskalab.bsky.social

07.05.2025 06:50 — 👍 7    🔁 1    💬 0    📌 0
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Ivaska lab members are at the Fibronectin GRC at the gorgeous Renaissance Hotel in Tuscany! Come say hi to (L-R) Michalis, Megan, Omkar, Gautier and Michal if you haven't already 😀

07.05.2025 06:44 — 👍 17    🔁 1    💬 0    📌 1
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Syöpä | Johanna Ivaska selvittää, miksi kaikki ihmiset eivät sairastu syöpään – ”Kukaan ei pysty suojaamaan itseään täysin” Kaikissa ihmisissä jotkut syövän esiasteet eivät kehity koskaan syöväksi, sanoo syöpätutkija Johanna Ivaska. Hän sanoo, että ihmiset voivat itse vaikuttaa syövän syntyyn korkeintaan kohtuullisesti.

Niin, miksi kaikki tupakoitsijat eivät sairastu keuhkosyöpään eikä uskollisinkaan auringonpalvoja välttämättä saa melanoomaa🤔. Tutkijamme Johanna Ivaskan mielenkiintoinen haastattelu @hs.fi :ssä (tilaajille).
#syöpä #syöpätutkimus
@ivaskalab.bsky.social @turkubioscience.bsky.social @utu.fi

24.04.2025 15:23 — 👍 13    🔁 4    💬 0    📌 0
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Featured image with Omkar Joshi - FocalPlane Featured image with Omkar Joshi - News

It’s #FluorescenceFriday and we are pleased to share this beautiful image from
@omkarjoshi.bsky.social. Read more about the image and Omkar’s research in our accompanying post: focalplane.biologists.com/2025/03/14/f...

14.03.2025 10:18 — 👍 18    🔁 3    💬 0    📌 1
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🎉 Great success for Turku Bioscience Centre at the 3MT competition!

Congrats to Rahul Birdar (@lahesmaalab.bsky.social) for securing 2nd place and Omkar Joshi (@ivaskalab.bsky.social) for being selected to represent @utu.fi in the international 3MT competition by the SANORD network! 👏 #3MT #SANORD

07.03.2025 10:01 — 👍 8    🔁 2    💬 1    📌 0
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Haven't registered for "Advances in mechanobiology" yet? No problem!! We've got you covered!!!
Just scan the QR code below or head over our website: themeshwork2020.wixsite.com/info/up-comi...
@drsarahboyle.bsky.social @mathildemathieu.bsky.social @ivaskalab.bsky.social @carstenschulte4.bsky.social

05.02.2025 17:28 — 👍 7    🔁 7    💬 0    📌 1
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We are hiring! We seek a motivated postdoc to investigate the ribosomal mechanisms underpinning dormancy and awakening across eukaryotes, using cutting-edge confocal microscopy, volumeEM, and omics. @lsiexeter.bsky.social. Interested? DM me or apply via: jobs.exeter.ac.uk/hrpr_webrecr...

28.01.2025 15:00 — 👍 9    🔁 8    💬 0    📌 0
Call for applications 2025 – Creation of new research groups at the Institut Pasteur | Research - Institut Pasteur

My regular reminder that there is an open call @pasteur.fr for junior group leader covering various axis (including topics related to development biology), open till Feb. 28th. Don't hesitate to DM me or reach out by email if you want to get more context.
research.pasteur.fr/fr/call/call...

26.01.2025 20:38 — 👍 34    🔁 29    💬 0    📌 0

@ivaskalab is following 20 prominent accounts