Joel Boerckel

Without considering the sources of claims, efforts at epistemic vigilance become play-acting. With LLMs, we don't know the sources.

Excellent thread from @mjcrockett.bsky.social

Science is properly more scrupulous than dogma. Dogma gives a charter to mistake, but the very breath of science is a contest with mistake, and must keep the conscience alive. Alas! the scientific conscience had got into the debasing company of money obligation and selfish respects.
Middlemarch 1872

if you are writing, and need to decide between making things easier for you or easier for your reader (such as using an acronym or cutting white space to fit in more words), always -always- choose your reader.

this tweet is not about AI, but it also is.

Let us call her Misty.

Life, regeneration & rebirth - sounds right to me 🦛❤️

#worldhippoday #yaptaz

NEW: Another NIH institute director hasn't been renewed — the director of NIAMS (arthritis, musculoskeletal and skin diseases institute).

That leaves a whopping 15 of 27 institutes and centers without a permanent director.

Whoa Guillaume, this is cool

❤️❤️❤️ congrats my friend!

“I think men’s minds are going to be changed in subtle ways because of [AI]; just how, though, I could hardly guess. But you can’t have the immense outward changes that they will cause without some inward ones…and it may be the spiritual alteration will be bad for us.”

With all their speed forward they may be a step backward in civilization—that is, in spiritual civilization. It may be that they will not add to the beauty of the world, nor to the life of men’s souls.

- Booth Tarkington, 1918

Yeah, we just write the best paper we can and then see who wants it. It’s our paper not theirs.

Beautiful! Congrats @efadial.bsky.social et al!

Thrilled to share our new bioRxiv preprint led by Eloise Fadial (@efadial.bsky.social) 🥳🎉! Using PRDM16 cKO mice, hiPSC models, scRNA-seq & CUT&RUN, Eloise shows that PRDM16 is a key genetic and epigenetic regulator of knee chondrogenesis and chondrocyte identity.
www.biorxiv.org/content/10.6...

That does sound lovely- my folks are nearby, will have to get the details for next time I’m back home

I have never been able to wait. Maybe I need more scotch

This sounds like a job for @cpane94.bsky.social, the mouse personal-trainer

Gotta be why it’s the only one in all caps 😂

Big Mig shifts the human dot to the right all by himself

I present the most interesting graph ever made.

HUMAN ON BICYCLE beats every other living thing.
www.scientificamerican.com/article/a-hu...

My brother wasn’t optimistic it could be done, but I didn’t take “wasn’t optimistic it could be done” for an answer.

😂❤️💯

“grant paper airplane” is perfection Amy

Congrats Dennis!

Our new paper just out!
pubs.acs.org/doi/10.1021/...

The NIH has indicated a “leniency” period for implementation of the Common Forms (SciENcv) May 2026:
grants.nih.gov/faqs#/common...

Note: the “warning” that says your materials are not in compliance is also displayed if you submit using the Common Forms. This warning can be ignored.

Look it’s Einstein notation day. IYKYK

Almost forgot my Hagoromo chalk this morning. A true crisis.
#BE550

New to ORS? 👋 Join our virtual New Member Orientation on Feb 4, 12–1 PM CT to dive into member benefits, networking opportunities, and more! Hear from a current member on ORS’s impact & join the live Q&A. Register: https://ors.memberclicks.net/nmo020426

To the light at the end.

“You are a slow learner, Winston."
"How can I help it? How can I help but see what is in front of my eyes? Two and two are four."
"Sometimes, Winston. Sometimes they are five. Sometimes they are three. Sometimes they are all of them at once. You must try harder. It is not easy to become sane.”