🦠Two pathogenic bacteria, Pseudomonas aeruginosa and Staphylococcus aureus, often grow together and worsen wound infection. But how are they affected by commensal bacteria?🔍
Read the full article🔗 https://doi.org/10.1099/jmm.0.002126
#JMM #Microbiology #Pathogen #Infection
26.02.2026 14:30 —
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Host Pathogen Interactions during Catheter-Associated Urinary Tract Infections
As a leading cause of healthcare-associated infections, catheter-associated urinary tract infections (CAUTIs) present a unique challenge due to the high prevalence of multidrug-resistant and polymicrobial pathogens. Distinct from uncomplicated UTIs, the insertion of a urinary catheter provokes tissue damage that triggers inflammation, plasma extravasation, and the deposition of host fibrinogen. This inflammatory response drives the robust recruitment of immune cells and plasma extravasation, leading to the accumulation of fibrinogen─a key coagulation protein─on the device and bladder epithelium. This fibrinogen-rich environment creates a unique niche for intricate host–pathogen interactions. Crucially, uropathogens exploit these deposits to establish persistent biofilms, while the protein scaffold simultaneously modulates host immunity. Understanding these mechanisms, particularly the role of fibrinogen-binding adhesins, is vital for developing targeted, antimicrobial-sparing therapeutics. In this perspective, we examine the strategies uropathogens employ to persist in the catheterized bladder, the corresponding host immune response, and emerging strategies to prevent CAUTI.
Ever wonder what really goes down in the microscopic battleground of a catheter-associated UTI? 🦠⚔️ Our new review unpacks the Host-Pathogen Interactions during CAUTIs. Thank you, Kurt Kohler and Alyssa La Bella @alabella14.bsky.social for putting this together!!! pubs.acs.org/doi/full/10....
25.02.2026 19:36 —
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Making good progress! #SciArt
24.02.2026 04:12 —
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more work in progress 🐦⬛✍🏻 grateful for this commission ✨ drawn with faber castell polychromos pencils
19.02.2026 16:11 —
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Structural and evolutionary insights into the isoprene monooxygenases
Abstract. Isoprene, a highly reactive biogenic volatile organic compound (VOC) emitted by terrestrial vegetation, influences atmospheric chemistry but its
Not all research moves fast — and not all valuable contributions are immediately obvious.
Some science is cumulative.
This isn’t fast-throughput work. It’s the kind that takes time — and makes future discoveries possible.
#uArctic_project
doi.org/10.1093/fems...
27.01.2026 10:11 —
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PhD student bioinformatics: Phage genomic modules: data mining, visualisation, and databasing
PhD position in Jena! Unique German-French collaboration to work on integrating phage genomic modules into VirJenDB.org - make sense of #phages, #big_data, #front_end, #back_end, #database. Please apply here 👇
jobs.uni-jena.de/jobposting/c...
12.01.2026 11:41 —
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