CortésLab

CortésLab

@corteslab.bsky.social

We study DNA topology, the action of topoisomerses and DNA break repair to understand genome organization, dynamics and stability @cniostopcancer.bsky.social https://repairome.bioinfo.cnio.es

133 Followers 178 Following 11 Posts Joined Oct 2025
5 months ago

Looking forward to reading that!

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5 months ago

Also: Research positions in the Ramsden lab. Post doctoral position - 5 years funding available. Cross-country collaborative, working closely with the groups of Gupta, Rothenberg, Wood, and Doublie.
Some example pubs from the last two post docs: PMIDs 37968395,35927262, 2963245, 30213916, 26240371

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5 months ago

In this screen the system is blind to HR. Repeating with an homologous template is in the pipeline.
Muchas gracias! 😘

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5 months ago

Thanks a lot Benjamin. Glad you like it!

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5 months ago

Thanks Iván! I also hope so 😀

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5 months ago

Thanks so much, Juanma! Excited to discuss the paper in a couple of weeks at the Social DNAing Webinar Series. Grateful for the invitation!

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5 months ago

Thanks Emilio!

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5 months ago

Thanks Nuria! Hope it's a useful resource for the cancer genomics field

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5 months ago
REPAIRome

Check out our web tool to see interactive networks of DSB repair genes, browse your gene of interest for its contribution to DSB repair profiles and analyze functional relationships based on similarities in repair patterns

Enjoy!!!

repairome.bioinfo.cnio.es

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5 months ago

Congratulations to all the people involved, also in
Ana Losada's
@rfleiro.bsky.social
@gmaci.bsky.social
labs
@cniostopcancer.bsky.social

Specially leading authors
Ernesto López de Alba
@israelsalguero.bsky.social
Daniel Giménez Llorente

Very proud of you!!!

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5 months ago

We provide:
- A catalog of how more than 18K genes affect DSB repair sequence outcomes induced by CRISPR-Cas9
- Examples of how it can be used at different levels, from identifying novel factors and functional relationships, to explaining mutational signatures in cancer

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5 months ago
Preview
A comprehensive genetic catalog of human double-strand break repair The analysis of DNA sequence outcomes provides molecular insights into double-strand break (DSB) repair mechanisms. Using parallel in-pool profiling of Cas9-induced insertions and deletions (indels) w...

Kickstarting our Bluesky🦋 account with great news!
Our REPAIRome study finally out today in
@science.org
www.science.org/doi/10.1126/...

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