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CortésLab

@corteslab.bsky.social

We study DNA topology, the action of topoisomerses and DNA break repair to understand genome organization, dynamics and stability @cniostopcancer.bsky.social https://repairome.bioinfo.cnio.es

131 Followers  |  178 Following  |  11 Posts  |  Joined: 03.10.2025
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Posts by CortésLab (@corteslab.bsky.social)

Looking forward to reading that!

09.10.2025 07:29 — 👍 0    🔁 0    💬 0    📌 0

Also: Research positions in the Ramsden lab. Post doctoral position - 5 years funding available. Cross-country collaborative, working closely with the groups of Gupta, Rothenberg, Wood, and Doublie.
Some example pubs from the last two post docs: PMIDs 37968395,35927262, 2963245, 30213916, 26240371

08.10.2025 15:08 — 👍 1    🔁 1    💬 0    📌 0

In this screen the system is blind to HR. Repeating with an homologous template is in the pipeline.
Muchas gracias! 😘

06.10.2025 08:14 — 👍 1    🔁 0    💬 0    📌 0

Thanks a lot Benjamin. Glad you like it!

06.10.2025 08:10 — 👍 0    🔁 0    💬 0    📌 0

Thanks Iván! I also hope so 😀

06.10.2025 08:09 — 👍 0    🔁 0    💬 0    📌 0

Thanks so much, Juanma! Excited to discuss the paper in a couple of weeks at the Social DNAing Webinar Series. Grateful for the invitation!

06.10.2025 08:08 — 👍 0    🔁 0    💬 0    📌 0

Thanks Emilio!

06.10.2025 08:01 — 👍 1    🔁 0    💬 0    📌 0

Thanks Nuria! Hope it's a useful resource for the cancer genomics field

06.10.2025 08:00 — 👍 1    🔁 0    💬 0    📌 0
REPAIRome

Check out our web tool to see interactive networks of DSB repair genes, browse your gene of interest for its contribution to DSB repair profiles and analyze functional relationships based on similarities in repair patterns

Enjoy!!!

repairome.bioinfo.cnio.es

04.10.2025 07:27 — 👍 3    🔁 1    💬 0    📌 0

Congratulations to all the people involved, also in
Ana Losada's
@rfleiro.bsky.social
@gmaci.bsky.social
labs
@cniostopcancer.bsky.social

Specially leading authors
Ernesto López de Alba
@israelsalguero.bsky.social
Daniel Giménez Llorente

Very proud of you!!!

04.10.2025 07:27 — 👍 3    🔁 0    💬 1    📌 0

We provide:
- A catalog of how more than 18K genes affect DSB repair sequence outcomes induced by CRISPR-Cas9
- Examples of how it can be used at different levels, from identifying novel factors and functional relationships, to explaining mutational signatures in cancer

04.10.2025 07:27 — 👍 0    🔁 0    💬 1    📌 1
Preview
A comprehensive genetic catalog of human double-strand break repair The analysis of DNA sequence outcomes provides molecular insights into double-strand break (DSB) repair mechanisms. Using parallel in-pool profiling of Cas9-induced insertions and deletions (indels) w...

Kickstarting our Bluesky🦋 account with great news!
Our REPAIRome study finally out today in
@science.org
www.science.org/doi/10.1126/...

04.10.2025 07:27 — 👍 77    🔁 27    💬 7    📌 1